This two-day, ITM-supported symposium brings oncologists and statisticians together to share research, discuss new ideas, ask questions, and provide solutions for cancer clinical trials. In the era of big data and precision medicine, it is crucial for interdisciplinary dialogue among clinical and quantitative scientists. The OncoStat Annual Symposium allows oncologists and statisticians to communicate their views on trial design and conduct, drug development, and translations to patient care. Symposium sessions will cover big data and genomics for oncology clinical trials, dose-finding designs, drug combinations, immune oncology clinical trials, and umbrella/basket oncology trials. This event is supported by the Institute for Translational Medicine at the University of Chicago and hosted by the UChicago’s Comprehensive Cancer Center, and Department of Public Health Sciences.