Mayo Clinic Center for Clinical and Translational Science

Mission Statement

Mayo Clinic Center for Clinical and Translational Science (CCaTS) connects researchers to the people, information and resources they need to keep medical science moving forward. CCaTS is a central hub for institutional advancement of research and education at Mayo Clinic. The center provides tools and expert consultation to support every aspect of medical research, including basic discovery science, clinical and community-engaged research, and late-stage application and commercialization.

At a Glance

4

Educational Resources Posted

37

Consortium News Stories Posted

2

Events Posted

1

Opportunities Posted

1471

Publications citing CTSA Program Grant

43

Users from Hub Registered
Programs

UL1 Award

KL2 Award

TL1 Award

Funded Years
2012 - 2015, 2017 - 2020
  • UL1

    UL1 Director
    Claudia
    Lucchinetti
    Physician Scientist; Professor of Neuroscience; Department Chair Neurology
    UL1 Administrator
    Laura
    Meiners
    Director of Research Operations
    ,
    Jennifer
    Weis
    Research Administrator

    Education

    KL2 Director
    David
    Warner
    Professor of Anesthesiology
    KL2 Administrator
    Carmen
    Silvano
    TL1 Director
    TL1 Administrator
    Carmen
    Silvano

    Communications

    Communications Representative
    Caitlin
    Doran
    Communications Specialist

    Enterprise Committees

    Integration Across Lifespan Voting Member
    Young
    Juhn
    Professor of Pediatrics and Director of Asthma Epidemiology Research Unit
    Methods and Processes Voting Member
    Rickey
    Carter
    Professor of Biostatistics
    Workforce Development Voting Member
    David
    Warner
    Professor of Anesthesiology
    Informatics Voting Member
    Hongfang
    Liu
    Collaboration and Engagement Voting Member
    Doubeni
    Chyke

    Common Metrics

    Primary CM Contact
    Katherine
    Cornelius
    Additional CM Contacts
    Laura
    Meiners
    Director of Research Operations

Consortium News

A Rochester company that developed a device that reduces the size of eye droplets by 60% won the grand prize of the Minnesota Cup on Monday night, beating nearly 2,000 other companies that entered what has become the largest statewide competition for startups in Minnesota. Led by a Mayo Clinic medical student, Nanodropper Inc. won the $50,000 grand prize, in addition to $25,000 for winning its

The microscope hovers over a small dish. It's attached to a laptop, so students don't need to press their faces against a microscope eyepiece. On the screen is a zebrafish egg. On hand to answer questions are scientists. The questions, however, are a little different from the ones they get from colleagues. "One of the questions I got was how does gravity work, and I was like, 'Oh that's a great

Beriberi, which affects metabolic, neurologic, cardiovascular, respiratory, gastrointestinal and musculoskeletal systems, was largely eradicated in developed countries more than 70 years ago. Over the past 20 years, Philip Fischer, M.D., has been engaged in health disparities research to find ways to do the same in countries where the disease persists today.

Educational Content

Mayo Clinic

Fundamentals of Clinical and Translational Science (FunCaTS) is a combination of 13 online modules strategically packaged together to enable medical professionals and allied health staff to expand their knowledge of the components of clinical and translational research. These components provide the fundamental knowledge to promote understanding of the process of bringing discoveries to the bedside

Mayo Clinic

Are you ready to take a deeper dive into the world of clinical and translational science? Essentials of Clinical and Translational Science (ECaTS) provides medical professionals with foundational knowledge of research terminology, research methods and processes, clinical epidemiology, and biomedical statistics. Upon completion, learners understand basic terminology and methodological concepts in

Mayo Clinic

Are you ready to take a deeper dive into the world of clinical and translational science? Essentials of Clinical and Translational Science (ECaTS) provides medical professionals with foundational knowledge of research terminology, research methods and processes, clinical epidemiology, and biomedical statistics. Upon completion, learners understand basic terminology and methodological concepts in

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Mayo Clinic

Sjӧgren's syndrome (SS), the second most common rheumatic disease contributing nine times the cost of a healthy person, has hallmark features of oral and ocular dryness due to salivary and lacrimal gland inflammation. Minor salivary glands, central to the pathogenesis and diagnosis of SS, contain mesenchymal stromal cells (MSCs). In other conditions MSCs are responsible for tissue repair and

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Mayo Clinic

Almost all cardiovascular variables that have been assessed at different times of day and night in humans have been found to have a day/night pattern, including blood pressure heart rate, and vascular endothelial function. These patterns result from the summation of predictable circadian effects with variable behavioral (e.g. sleep, exercise, and meal intake) and environmental (e.g. temperature)

Opportunities

Charge The Director of Continuous Quality Improvement and Program Evaluation for the Mayo Clinic College of Medicine and Science (MCCMS) provides strategic and operational direction to implement a comprehensive, integrated and sustainable quality improvement and evaluation system across the College. This system should provide each school within MCCMS with ready access to the synthesis of key data

Poster Sessions

Mayo Clinic

The Mayo Clinic COVID-19 Task Force was established to enable, coordinate, and catalog research studies and practice demands of COVID-19. The task force manages research across the whole translational spectrum, aligning competing and duplicative studies to steward research resources and coordinates Institutional Review Board, Center for Clinical and Translational Science (CCaTS) Office of Clinical

Virginia Commonwealth University
University of Nebraska Medical Center
University Of Washington
University Of Alabama At Birmingham
University Of North Carolina Chapel Hill
Johns Hopkins University
Mayo Clinic
Oregon Health and Science University

Many clinical questions have arisen with the COVID-19 pandemic, from who is at greatest risk for COVID-19 infection to adverse outcomes if infected to how COVID-19 has impacted healthcare utilization patterns. To help answer these questions, and many more, the National COVID Cohort Collaborative (N3C) has integrated real-world clinical observations from across the nation into a harmonized database

Mayo Clinic Office of Translation to Practice
Mayo Clinic

The Office of Translation to Practice (OTP) is housed in the Center for Clinical and Translational Sciences at Mayo Clinic. Established in 2015, the office is tasked with developing and managing novel tools, mechanisms, and processes to facilitate and accelerate the translation of products, such as drugs, biological agents, and medical devices, into practice. Since its inception, OTP is credited

Publications

Higher unacylated ghrelin and insulin sensitivity following dietary restriction and weight loss in obese humans

Unacylated ghrelin (UnAG) modulates insulin sensitivity. Low plasma UnAG occurs in obesity and potentially contributes to obesity-associated insulin resistance. We hypothesized that improvements in insulin sensitivity in obese people induced by moderate caloric restriction (CR) may be paralleled and

Regulation of direct adipose tissue free fatty acid storage during mixed meal ingestion and high free fatty acid concentration conditions

We found that direct free fatty acid (FFA) storage (fatty acid cycling back into adipose tissue) in leg vs. abdominal subcutaneous fat is related to regional differences in adipose tissue diacylglycerol acyltransferase (DGAT) activity under high-FFA conditions and to differences in adipose tissue

Timeline of Rapid Eye Movement Sleep Behavior Disorder in Overt Alpha-Synucleinopathies

The aim was to analyze the timeline, prevalence, and survival of rapid eye movement (REM) sleep behavior disorder (RBD) in patients who developed alpha-synucleinopathies (Parkinson disease, dementia with Lewy bodies, and Parkinson disease dementia) compared with age- and sex-matched controls in a

Research and Operational Tools

Mayo Clinic

The Rochester Epidemiology Project (REP) is a collaboration between health care providers in Minnesota and Wisconsin.

Mayo Clinic

Clinical trials bridge the gap between research and patient care and help a medical discovery become a therapy. The clinical trial journey is long and complicated, with many steps along the way, and it can be challenging to describe this process to patients and research volunteers, or to colleagues who are unfamiliar with clinical research.

Title Authored Sort ascending Content type
Mayo Clinic med student startup, Nanodropper, wins MN Cup top prize September 21, 2021 Consortium News
Mayo Scientists, Teachers Partner to Bring Science Experiences to Students September 14, 2021 Consortium News
Mayo's Dr. Fischer wants to improve the health of children everywhere August 24, 2021 Consortium News
Clinical trials from a community perspective: "Authenticity is priceless" August 13, 2021 Consortium News
Keeping translational science on the fast track to curb COVID-19 pneumonia July 20, 2021 Consortium News
Mayo graduate charts a career blending science with patient care July 14, 2021 Consortium News
How clinical trials work: COVID-19 and beyond June 22, 2021 Consortium News
Giving youth a voice in pediatric health research May 19, 2021 Consortium News
Study finds virtual community platform beneficial for engagement in health research April 27, 2021 Consortium News
Balancing Damage and Protection, Neutrophils May Lead to Cell Aging, Mayo study says April 07, 2021 Consortium News
Four women who 'make health equity research run' at Mayo Clinic March 16, 2021 Consortium News
Community-based care key to COVID-19 rapid response in underserved communities March 09, 2021 Consortium News
CTSA Visiting Scholars Program - What salivary gland mesenchymal stromal cells teach us about the pathogenesis and treatment of Sjӧgren's Syndrome February 26, 2021 Event
CTSA Visiting Scholars Program - Circadian Rhythms and Cardiovascular Risk February 26, 2021 Event
Rare esophageal cancer hits younger patients especially hard, Mayo study finds January 26, 2021 Consortium News
Fundamentals of Clinical and Translational Science (FunCaTS) January 10, 2021 Educational Content
Essentials of Clinical and Translational Science (ECaTS) January 10, 2021 Educational Content
How Mayo research is addressing COVID-19 health disparities in Black communities December 15, 2020 Consortium News
Mayo Clinic launches COVID-19 Vaccine Registry November 24, 2020 Consortium News
New research shows markers in donor kidneys that could reduce risks November 17, 2020 Consortium News
Mayo Clinic COVID-19 Task Force October 29, 2020 Poster
Assessing the Impact of COVID-19 on Immunocompromised Persons: N3C ImmunoSuppressed/Compromised Clinical Domain Team October 29, 2020 Poster
Health disparities curricula an “opportunity to be seized upon” in resident training September 15, 2020 Consortium News
Mayo Clinic student-led startup lands Air Force contract August 31, 2020 Consortium News
Minority communities attend Mayo Clinic COVID-19 virtual town halls in Arizona August 03, 2020 Consortium News
A pioneering Hispanic health conference, two years in the making July 28, 2020 Consortium News
Randomized Controlled Trial of Losartan for Outpatients with COVID-19 July 27, 2020 Covid Study
Mayo partnership gets creative to reach vulnerable populations, isolated communities July 22, 2020 Consortium News
The Rochester Epidemiology Project (REP) Portal July 01, 2020 Research or Operational Tool
The Clinical Trial Journey July 01, 2020 Research or Operational Tool
Fishing for solutions to COVID-19 challenges June 15, 2020 Consortium News
Mayo researchers, minority communities team up to combat COVID-19 health disparities May 27, 2020 Consortium News
Training that increases research knowledge and confidence also boosts academic productivity March 12, 2020 Consortium News
Preaching from the heart: Mayo KL2 scholar uses pulpit to promote heart health February 26, 2020 Consortium News
Embracing clinical research with 'both feet and hands' February 18, 2020 Consortium News
New Mayo Clinic Proceedings "The Compass" offers direction on bioethics issues in medicine February 11, 2020 Consortium News
The Making of an Expert February 03, 2020 Consortium News
Mayo's ‘Bioethics at the Cinema’ Event Features Double Lung Transplant Patient January 23, 2020 Consortium News
Mayo InSciEd Out program teaches students how to test the effects of vaping on zebrafish January 16, 2020 Consortium News
KL2 scholar examines post menopause as key factor in endometrial cancer December 26, 2019 Consortium News
It’s predator versus predator at Mayo's Alligator Tank health care innovation competition December 11, 2019 Consortium News
Mayo Pediatric Advisory Board Gives Kids a Voice in Research November 21, 2019 Consortium News
Mayo student a finalist in Collegiate Inventors Competition October 30, 2019 Consortium News
Mayo innovators design adjustable fracture nail to improve patient outcomes October 21, 2019 Consortium News
Biostatistician keeps Mayo research ship-shape September 19, 2019 Consortium News
Mayo fellow already an internationally recognized expert on celiac disease September 10, 2019 Consortium News
CCaTS Office of Translation to Practice Accelerating the Cycle of Innovation to Impact August 22, 2019 Poster
Director, Continuous Quality Improvement & Program Eval (MCCMS) June 20, 2019 Opportunity
Essentials of Clinical and Translational Science (ECaTS) February 18, 2019 Educational Content
Fundamentals of Clinical and Translational Science (FunCaTS) February 18, 2019 Educational Content