UCLA Clinical and Translational Science Institute

UCLA Clinical and Translational Science Institute

Mission Statement

The mission of the UCLA CTSI is to produce and implement innovations that impact the greatest health needs of Los Angeles and the nation. Our vision is to catalyze research that translates discoveries into tangible improvements in health care, disease prevention, and health in our community.

At a Glance

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Educational Resources Posted

4

Consortium News Stories Posted

3

Events Posted

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Opportunities Posted

130

Publications citing CTSA Program Grant

29

Users from Hub Registered

Consortium News

A clinical trial at UC Davis Health and six other sites showed that a cellular therapy offers promise for patients with late-stage Duchenne muscular dystrophy (DMD), a rare genetic disorder causing muscle loss and physical impairments in young people.

In 2017, Jeffrey Bazarian, M.D., M.P.H., a concussion researcher at the University of Rochester Medical Center, wanted to pull together a national network of concussion clinics to run multi-site clinical trials. He turned to the University of Rochester Clinical and Translational Science Institute (UR CTSI) and Trial Innovation Network (TIN) for help and ended up connecting with a group already

One of the first synergy papers supported by the CLIC and CTSA consortium was published in the Journal of Clinical and Translational Science. Abstract: A primary barrier to translation of clinical research discoveries into care delivery and population health is the lack of sustainable infrastructure bringing researchers, policymakers, practitioners, and communities together to reduce silos in
Hwang flyer_UCLA CTSI
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University Of California Los Angeles

Dr. Hwang is an Attending Radiologist within the Division of Body Imaging, Director of Neonatal Imaging, and an Assistant Professor of Radiology at the University of Pennsylvania. Her KL2 project is on the validation of quantitative brain contrast enhanced ultrasound for evaluation of brain health in porcine model and infants of brain injury. Required registration at https://uclahs.fyi/Hwang to

Hicks - UCLA Visiting Scholar
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University Of California Los Angeles

Dr. Steven Hicks, MD, PhD is an Associate Professor of Pediatrics at Penn State University. His translational research identifies molecular biomarkers that inform child growth, neurodevelopment and disease. ABSTRACT: Mild traumatic brain injury (mTBI) is extremely common among adolescents, who suffer disproportionately from prolonged concussion symptoms - a condition for which no biologic test

California Precision Health Summit Feb. 6-7 at UCLA
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University Of California Los Angeles

Please join us for the inaugural California Precision Health Summit Feb. 6-7 at UCLA. The summit will focus on cancer: tumor evolution, liquid biopsies, and immuno-oncology. Featured speakers include: - Christina Curtis, PhD, MSc - Caroline Dive, CBE - Antoni Ribas, MD, PhD - Charles Swanton, FRS, FMedSci, FRCP - Peter Van Loo, PhD Register online by Dec. 14

Poster Sessions

University Of California Los Angeles

Recognizing the diversity of populations within California and the disproportionate burden of COVID-19 on minority and low income communities, we have formed a statewide community-partnered collaborative funded by the NIH/NHLBI to address disparities in COVID-19 knowledge, awareness, and communication; vaccine trial participation; and vaccine hesitancy and accessibility. The statewide

Precision Health and Population Health Programs at UCLA CTSI, A Multi-institutional CTSA Hub
University Of California Los Angeles

UCLA CTSI Population Health Program Population health seeks to identify and address variation in needs, care experiences, intervention efficacy, and outcomes for a defined group. In health systems, closing gaps often require collective actions of complex interdependent medical and social care systems in communities. The CTSI co-developed a Population Health Program with the local health department

Publications

A Multi-Dimensional Characterization of Aging and Wellbeing Among HIV-Positive Adults in Malawi

There is relatively little research on aging with HIV and wellbeing in sub-Saharan Africa. A cross-sectional survey was implemented in Malawi; eligible respondents were ≥ 30 years old and on ART for ≥ 2 years. Univariate and multiple regression analyses were stratified by age (younger adults: aged

Treatment outcomes and costs of a simplified antiviral treatment strategy for hepatitis C among monoinfected and HIV and/or hepatitis B virus-co-infected patients in Myanmar

Access to hepatitis C virus (HCV) testing and treatment is limited in Myanmar. We assessed an integrated HIV and viral hepatitis testing and HCV treatment strategy. Sofosbuvir/velpatasvir (SOF/VEL) ± weight-based ribavirin for 12 weeks was provided at three treatment sites in Myanmar and sustained

Occult Colonic Perforation in a Patient With Coronavirus Disease 2019 After Interleukin-6 Receptor Antagonist Therapy

Interleukin-6 blockade (IL-6) has become a focus of therapeutic investigation for the coronavirus disease 2019 (COVID-19). We report a case of a 34-year-old with COVID-19 pneumonia receiving an IL-6 receptor antagonist (IL-6Ra) who developed spontaneous colonic perforation. This perforation occurred

Title Authored Sort ascending Content type
UC Davis CTSC supported cellular therapy study improves Duchenne muscular dystrophy March 17, 2022 Consortium News
Expansion of Universal Consent to our UCLA Patients November 05, 2021 Poster
UR CTSI Helps Make Connection that Spurs $10M Grant to Study Concussion October 12, 2021 Consortium News
CTSA Visiting Scholars - "Brain Contrast Enhanced Ultrasound" - Misun Hwang, MD March 09, 2021 Event
CTSA Visiting Scholars Program: "Spit Signals: Concussion Insights from Saliva RNA" December 04, 2020 Event
Share, Trust, Organize, Partner COVID-19 California Alliance, or STOP COVID-19 CA: A Community Engaged Collaborative to address COVID-19 Education, Vaccine Trial Participation and Vaccine Acceptability October 22, 2020 Poster
Bridging the gap between research, policy, and practice: Lessons learned from academic–public partnerships in the CTSA network July 21, 2020 Consortium News
Mavrilimumab to reduce progression of acute respiratory failure in patients with severe COVID-19 pneumonia and systemic hyper-inflammation May 08, 2020 Covid Study
A Multicenter, Adaptive, Randomized Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Adults April 20, 2020 Covid Study
UC BRAID Collaborations Work to Impact Health throughout California February 14, 2020 Consortium News
California Precision Health Summit December 02, 2019 Event
Former KL2 Scholar Finds Mitochondria's Activity in Lung Cancer May Predict Response to Treatment November 01, 2019 Consortium News
Precision Health and Population Health Programs at UCLA CTSI, a Multi-Institutional CTSA Hub August 23, 2019 Poster
UNIVERSITY OF CALIFORNIA LOS ANGELES February 05, 2019 CTSA Program Hub