Center for Clinical and Translational Science

UIC circle mark, University of Illinois at Chicago

Mission Statement

The University of Illinois at Chicago (UIC) Center for Clinical and Translational Science (CCTS) seeks to catalyze translational research, locally and nationally, as part of a national network to improve individual and population health. Since our initial funding by the NIH in 2009, the CCTS has been a catalyst for mobilizing institutional support and resources to enhance clinical translational research and expand multidisciplinary training programs to increase workforce diversity and promote team science. The overarching goal—and driving focus—of the CCTS is to improve population health, particularly among minorities and underserved populations. Our high-quality multidisciplinary clinical and translational research, spanning T1-T4 and paired with strengths in community engagement and implementation science and appreciation for the social determinants of health, help to accelerate discoveries into practice and policy.

At a Glance


Educational Resources Posted


Consortium News Stories Posted


Events Posted


Opportunities Posted


Publications citing CTSA Program Grant


Users from Hub Registered

UL1 Award

KL2 Award

TL1 Award

Funded Years
2012 - 2014, 2016 - 2021
Connect with Us

Consortium News

Episode Summary: Dr. Tara Mehta and her partners at Urban Initiatives talk about their efforts to improve children’s mental health by teaching recreational staff how to promote social-emotional learning during recess. Featured Researchers & Partners: Tara Mehta, PhD Associate Professor of Clinical Psychology Department of Psychiatry, UIC College of Medicine Consultant, CCTS Community Engagement &

Amy Lasek, a former UIC Center for Clinical and Translational Science pilot grant awardee (2018-2020) and researcher at UIC’s Center for Alcohol Research in Epigenetics, was published in the journal Translational Psychiatry. The study, “Transcriptomics identifies STAT3 as a key regulator of hippocampal gene expression and anhedonia during withdrawal from chronic alcohol exposure,” builds on her

Researchers at the University of Illinois Chicago have identified a potent new antiviral compound that can effectively block viral replication in human cells. The discovery, spearheaded by the UICentre for Drug Discovery, could lead to the development of a new therapy to treat patients infected by SARS-CoV-2, the virus that causes COVID-19. The researchers say it could be a powerful new weapon in

Educational Content

University Of Illinois At Chicago
The goal of any community-academic research collaboration is equitable partnership. CIRTification teaches community research partners about the importance of protecting research participants while enhancing the overall contribution they are able to make to their respective research teams. In community-engaged research, academic researchers collaborate with different partners from non-academic


The Research Associate II, Clinical Research Center may assist with all studies supported through the Clinical Research Center. The Clinical Research Center (CRC) provides the UIC research community with a core of clinical research professionals. These individuals possess specialized training to provide a full array of clinical research services including, but not limited to: initial planning and

Biomedical Informatics Senior Research Specialist UIC Center for Clinical and Translational Science The Biomedical Informatics Senior Research Specialist contributes to the conceptualization, design, development and delivery of biomedical informatics research projects, addressing all areas of clinical and translational science for the Center for Clinical & Translational Science (CCTS). This

Poster Sessions

Drug Discovery at UIC
University Of Illinois At Chicago
UICentre is a campus-wide small molecule drug discovery initiative at the University of Illinois at Chicago associated with the Center for Clinical and Translational Sciences (CTSA). Using established core instrumentation and with modest annual support, UICentre was conceived to utilize existing resources to leverage the expertise of scientist and clinicians teams across campus in collaborative


Family history of breast cancer in men with non-BRCA male breast cancer: implications for cancer risk counseling

The role of genetic predisposition in male breast cancer (MBC) patients who test negative for a BRCA mutation is unclear. The aim of this study is to define the association between MBC and family history of breast cancer in patients without mutations in BRCA1 or BRCA2. We conducted an unmatched case

In pursuit of the triple crown: mechanism-based pharmacodynamic modelling for the optimization of three-drug combinations against KPC-producing Klebsiella pneumoniae

Optimal combination therapy for Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-Kp) is unknown. The present study sought to characterize the pharmacodynamics (PD) of polymyxin B (PMB), meropenem (MEM) and rifampin (RIF) alone and in combination using a hollow fibre infection

Targets of biologic disease-modifying antirheumatic drugs and risk of multiple myeloma

Several commonly used immune-suppressing biologic drugs target proteins and cytokines involved in myeloma pathogenesis. Our objective was to determine whether targeted biologic disease-modifying antirheumatic drugs (DMARDs) are associated with risk of multiple myeloma (MM). We conducted a nested

Research and Operational Tools

University Of Illinois At Chicago

About the Program

The popular CIRTification program is now available for implementation at the institutional level. CIRTification is a free, web-based human research protections training program tailored specifically to the needs and roles of community research partners.

Title Authored Sort ascending Content type
Dr. Tara Mehta & Urban Initiatives: A partnership to promote children’s mental health October 25, 2021 Consortium News
UIC research identifies potential pathways to treating alcohol use disorder, depression June 29, 2021 Consortium News
Clinical Research Center Research Associate II April 14, 2021 Opportunity
Novel COVID-19 drug blocks viral replication March 25, 2021 Consortium News
‘Zombie’ genes? Research shows some genes come to life in the brain after death March 23, 2021 Consortium News
Researchers publish call to action for research ethics in the time of COVID-19 and BLM March 02, 2021 Consortium News
Retrained generic antibodies can recognize SARS-CoV-2 February 25, 2021 Consortium News
Reduced Adult Neurogenesis Linked with Alzheimer’s Disease February 22, 2021 Consortium News
Study looks at menopause, cognitive function in women of color, including women with HIV February 17, 2021 Consortium News
Biomedical Informatics Senior Research Specialist UIC,CCTS January 07, 2021 Opportunity
What’s It Like To Volunteer In A COVID-19 Vaccine Trial? October 06, 2020 Consortium News
CIRTification Online August 24, 2020 Research or Operational Tool
UIC vaccine study opens today August 24, 2020 Consortium News
Clinical Research Center director says social unrest and COVID pandemic leading to surges of anxiety and depression in Black communities July 25, 2020 Consortium News
Bridging the gap between research, policy, and practice: Lessons learned from academic–public partnerships in the CTSA network July 21, 2020 Consortium News
Popular human research protection training program, CIRTification, now available online for institutional use July 02, 2020 Consortium News
A Multicenter, Adaptive, Randomized Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Adults April 20, 2020 Covid Study
UICentre drug discovery @ UIC September 06, 2019 Poster
CIRTification Training Program for Human Research Protections February 08, 2019 Educational Content