Center for Clinical and Translational Science

UIC circle mark, University of Illinois at Chicago

Mission Statement

The University of Illinois at Chicago (UIC) Center for Clinical and Translational Science (CCTS) seeks to catalyze translational research, locally and nationally, as part of a national network to improve individual and population health. Since our initial funding by the NIH in 2009, the CCTS has been a catalyst for mobilizing institutional support and resources to enhance clinical translational research and expand multidisciplinary training programs to increase workforce diversity and promote team science. The overarching goal—and driving focus—of the CCTS is to improve population health, particularly among minorities and underserved populations. Our high-quality multidisciplinary clinical and translational research, spanning T1-T4 and paired with strengths in community engagement and implementation science and appreciation for the social determinants of health, help to accelerate discoveries into practice and policy.

At a Glance

1

Educational Resources Posted

17

Consortium News Stories Posted

1

Events Posted

2

Opportunities Posted

43

Publications citing CTSA Program Grant

42

Users from Hub Registered
Programs

UL1 Award

KL2 Award

TL1 Award

Funded Years
2012 - 2014, 2016 - 2021
Connect with Us

Consortium News

Episode Summary Fitness tracking devices, like FitBit and Apple watch, first hit the market around 2015. As a practicing psychiatrist and neuroscientist, Dr. Alex Leow was fascinated by this new technology and began to ask herself- if we can make data trackers for the human body, why not the human brain? Leow, longtime collaborator of former pilot awardee and CCTS clinical research support unit
University of Illinois Chicago researchers have developed a compound that may one day offer hope for pancreatic cancer treatment. A pre-clinical study of the experimental compound shows that it more than doubles the average survival time for mice with pancreatic cancer, and that survival time was extended further when combined with immunotherapy. Led by Ajay Rana, professor of surgery at the UIC

Episode Summary Physical activity can prove particularly challenging for frail older adults. And while there are many effective interventions to promote physical activity in this population, few end up translating from the research setting to the general public on a large scale. In this episode, former CCTS pilot awardees Drs. Jessie Chin, Kelly Quinn, David Marquez and Naoko Muramatsu discuss

Educational Content

University Of Illinois At Chicago
The goal of any community-academic research collaboration is equitable partnership. CIRTification teaches community research partners about the importance of protecting research participants while enhancing the overall contribution they are able to make to their respective research teams. In community-engaged research, academic researchers collaborate with different partners from non-academic
EQuaTR Logo
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Northwestern University At Chicago
The 2022 EQuaTR conference offers the opportunity for clinical research staff to learn from leaders in the field, gaining practical knowledge on current trends and issues in clinical research. EQuaTR is presented by the NUCATS Institute, The Institute for Translational Medicine, and the UIC Center for Clinical and Translational Science.

Opportunities

The Research Associate II, Clinical Research Center may assist with all studies supported through the Clinical Research Center. The Clinical Research Center (CRC) provides the UIC research community with a core of clinical research professionals. These individuals possess specialized training to provide a full array of clinical research services including, but not limited to: initial planning and

Biomedical Informatics Senior Research Specialist UIC Center for Clinical and Translational Science The Biomedical Informatics Senior Research Specialist contributes to the conceptualization, design, development and delivery of biomedical informatics research projects, addressing all areas of clinical and translational science for the Center for Clinical & Translational Science (CCTS). This

Poster Sessions

Drug Discovery at UIC
University Of Illinois At Chicago
UICentre is a campus-wide small molecule drug discovery initiative at the University of Illinois at Chicago associated with the Center for Clinical and Translational Sciences (CTSA). Using established core instrumentation and with modest annual support, UICentre was conceived to utilize existing resources to leverage the expertise of scientist and clinicians teams across campus in collaborative

Publications

Family history of breast cancer in men with non-BRCA male breast cancer: implications for cancer risk counseling

The role of genetic predisposition in male breast cancer (MBC) patients who test negative for a BRCA mutation is unclear. The aim of this study is to define the association between MBC and family history of breast cancer in patients without mutations in BRCA1 or BRCA2. We conducted an unmatched case

Depressive symptoms, mental health-related quality of life, and survival among older patients with multiple myeloma

To examine the impact of pre-diagnosis depressive symptoms and mental health-related quality of life (HRQOL) on survival among older patients with multiple myeloma (MM). We performed a retrospective cohort study using the Surveillance, Epidemiology, and End Results-Medicare Health Outcomes Survey

A coup d'état by NDM-producing Klebsiella pneumoniae overthrows the major bacterial population during KPC-directed therapy

The objective of this study was to utilize a co-culture hollow-fiber infection model (HFIM) to characterize the interplay between a small, difficult-to-detect, New Delhi metallo-β-lactamase-producing Klebsiella pneumoniae (NDM-Kp) minor population and a larger K. pneumoniae carbapenemase (KPC)

Research and Operational Tools

University Of Illinois At Chicago

About the Program

The popular CIRTification program is now available for implementation at the institutional level. CIRTification is a free, web-based human research protections training program tailored specifically to the needs and roles of community research partners.

Title Authored Sort ascending Content type
Enhancing Quality in the Translational Research (EquaTR) Workforce Conference April 06, 2022 Event
Podcast: "Fine-tuning" innovations to predict manic episodes in bipolar disorder March 22, 2022 Consortium News
Lab results show promise for future pancreatic cancer treatment February 21, 2022 Consortium News
Podcast: "Virtual coaching to increase physical activity in frail older adults" February 17, 2022 Consortium News
Podcast: "Examining sex differences in binge drinking habits" January 14, 2022 Consortium News
Dr. Tara Mehta & Urban Initiatives: A partnership to promote children’s mental health October 25, 2021 Consortium News
UIC research identifies potential pathways to treating alcohol use disorder, depression June 29, 2021 Consortium News
Clinical Research Center Research Associate II April 14, 2021 Opportunity
Novel COVID-19 drug blocks viral replication March 25, 2021 Consortium News
‘Zombie’ genes? Research shows some genes come to life in the brain after death March 23, 2021 Consortium News
Researchers publish call to action for research ethics in the time of COVID-19 and BLM March 02, 2021 Consortium News
Retrained generic antibodies can recognize SARS-CoV-2 February 25, 2021 Consortium News
Reduced Adult Neurogenesis Linked with Alzheimer’s Disease February 22, 2021 Consortium News
Study looks at menopause, cognitive function in women of color, including women with HIV February 17, 2021 Consortium News
Biomedical Informatics Senior Research Specialist UIC,CCTS January 07, 2021 Opportunity
What’s It Like To Volunteer In A COVID-19 Vaccine Trial? October 06, 2020 Consortium News
CIRTification Online August 24, 2020 Research or Operational Tool
UIC vaccine study opens today August 24, 2020 Consortium News
Clinical Research Center director says social unrest and COVID pandemic leading to surges of anxiety and depression in Black communities July 25, 2020 Consortium News
Bridging the gap between research, policy, and practice: Lessons learned from academic–public partnerships in the CTSA network July 21, 2020 Consortium News
Popular human research protection training program, CIRTification, now available online for institutional use July 02, 2020 Consortium News
A Multicenter, Adaptive, Randomized Blinded Controlled Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Adults April 20, 2020 Covid Study
UICentre drug discovery @ UIC September 06, 2019 Poster
CIRTification Training Program for Human Research Protections February 08, 2019 Educational Content
UNIVERSITY OF ILLINOIS AT CHICAGO February 05, 2019 CTSA Program Hub