University of Pennsylvania
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To reduce the barriers that confront faculty in their pursuit of such research.
At a Glance
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UL1 Award
KL2 Award
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UL1
UL1 Administrator
LORRISCHIERIEducation
KL2 Director
KL2 Administrator
LORRISCHIERITL1 Director
TL1 Administrator
LORRISCHIERIEnterprise Committees
Integration Across Lifespan Voting Member
Methods and Processes Voting Member
J. RichardLandisProfessor of Biostatistics, Director, Division of BiostatisticsWorkforce Development Voting Member
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J. RichardLandisProfessor of Biostatistics, Director, Division of Biostatistics
Educational Content
We are all facing different and difficult challenges as we confront the COVID-19 pandemic. In order to support you in this time of uncertainty, the University of Pennsylvania is sharing this free and unique version of Dr. Karen Reivich’s “Resilience Skills” course from the Specialization Foundations of Positive Psychology. Learn how to incorporate resilience interventions into your personal and
Events
KL2 awardees from Clinical and Translational Science Centers (CTSA) present virtual lectures as part of the CTSA Visiting Scholar Program. Melissa Barker-Haliski, PhD from the University of Washington, hosted by the University of Pennsylvania will present her research on the "Impact of Chronic Seizures on Cognitive and Neuropsychiatric Comorbidities in AD-Associated Preclinical Models."
This five-day course includes short lectures by expert Penn faculty and hands-on training and demonstrations. Lecture Topics: Introduction to stemcells Reprogramming methods and characterization ofiPSCs Gene editing methodologies and CRISPR/Cas9 design andconstruction Hepatocyte differentiation from PSCs and fibroblast to hepatocyte differentiation Cardiomyocyte differentiation andcharacterization
Publications
Polygenic Risk of Psychiatric Disorders Exhibits Cross-trait Associations in Electronic Health Record Data From European Ancestry Individuals
Prediction of disease risk is a key component of precision medicine. Common traits such as psychiatric disorders have a complex polygenic architecture, making the identification of a single risk predictor difficult. Polygenic risk scores (PRSs) denoting the sum of an individual's genetic liability
Evaluation of Vascular Reactivity of Maternal Vascular Adaptations of Pregnancy With Quantitative MRI: Pilot Study
Abnormal maternal vascular function during pregnancy stemming from systemic endothelial dysfunction (EDF) has a central role in the pathophysiology of preeclampsia (PE). To utilize quantitative MRI to investigate changes in physiological measures of vascular reactivity during normal pregnancy, and
Genetic skin disorders: The value of a multidisciplinary clinic
Genodermatoses are inherited disorders with skin manifestations and can present with multisystem involvement, resulting in challenges in diagnosis and treatment. To address this, the expertise of dermatology and clinical genetics through a multidisciplinary clinic (Genodermatoses Clinic) were