Balancing Damage and Protection, Neutrophils May Lead to Cell Aging, Mayo study says

Image
Image Credit
Mayo Clinic
Additional Text
Medical illustration of senescent cells, greenish, among normal cells.
Organization

The action of an immune cell called a neutrophil may contribute to tissue aging, according to a new study. As neutrophils do their job, they may damage chromosomes in nearby cells which, over time, may lead to cellular senescence. This new concept may help clarify cell aging. It also suggests targeting neutrophils might be helpful in treatment of age-related disease.

This research was funded, in part, by the Mayo Clinic Center for Clinical and Translational Science.

Organization
CTSA Program In Action Goals
Goal 4: Innovate Processes to Increase the Quality and Efficiency of Translational Research, Particularly of Multisite Trials