University Of Utah
- The CCTS is the home for clinical and translational science in our institutions, the state of Utah, and within the Mountain West Region. It builds on our strengths in genetics and bioinformatics to translate promising bench science into practices that improve human health.
The center serves as an academic home for clinical and translational research, developing innovative health services for the community and health researchers, and training a new generation of clinical and translational investigators. Four foundations of discovery compose the center: Clinical Trials Support, Population Health, Precision Medicine, and Workforce Development, and these foundations provide support for T1 to T4 research.
Vasculitis refers to a group of rare diseases that involve inflammation of blood vessels, which disrupts blood flow and often causes damage to the body’s organs. The cause of most forms of vasculitis remains unknown, and treatments involve the use of strong medications that can have serious side effects. The Vasculitis Clinical Research Consortium (VCRC) is an international, multicenter clinical
The porphyrias are a group of rare, inherited disorders, each caused by a deficiency with one of eight enzymes necessary to produce heme, an important component of hemoglobin and other proteins. The porphyrias are classified as either acute hepatic (liver) or cutaneous (skin); the former is characterized generally by acute attacks of severe abdominal pain accompanied by nausea, vomiting and other
The Hyperphenylalaninemia Disorders Consortium studies the health, neurologic, cognitive, neuropsychiatric, patient-reported and quality-of-life outcomes in individuals with chronic elevations of the amino acid phenylalanine in blood (hyperphenylalaninemia). Elevated blood phenylalanine is typically detected at birth in the United States through newborn screening and is caused by inherited
Leukodystrophies are a complex, often progressive group of disorders affecting the white matter of the brain due to the loss or absence of myelin, the lipid membrane that insulates axons in the central nervous system. Despite advances in the diagnosis of these disorders, they remain widely under-recognized, with unmet gaps in clinical care and curative therapeutics. The Global Leukodystrophy
Eosinophilic esophagitis, eosinophilic gastritis, eosinophilic gastroenteritis and eosinophilic colitis are disorders in which a type of immune cells (called eosinophils) build up in the digestive tract, causing tissue damage to the esophagus, stomach or colon. These disorders are painful and lifelong, and they make it hard or impossible for people to eat many or all foods. The Consortium of
The Brain Vascular Malformation Consortium (BVMC) focuses on three rare brain conditions: familial cerebral cavernous malformation (CCM), Sturge-Weber syndrome (SWS), and hereditary hemorrhagic telangiectasia (HHT). These disorders are poorly understood, are costly to manage, and can cause serious complications such as hemorrhages, seizures, and problems with spinal cord, nerve or brain function
- University Of Utah
Racial/ethnic minority, low socioeconomic status (SES) and rural populations suffer profound health inequities across a wide variety of diseases and conditions, as well as a disproportionate burden of the negative health consequences of the COVID-19 pandemic. Latinos make up ~14% of the Utah population compared to ~28 of Utah’s COVID-19 cases, and the case rate is over 3-fold higher in
- May 21, 2020A New Focus Even though we as a group are introverted scientists, I think we are learning how much of our routine is predicated on social interaction. We are always talking with colleagues and walking over to the next lab for a piece of advice or to borrow some trivial reagent. It’s so important to be able to think out loud or ask a colleague about some detail. This is all much more difficult
The Greater Plains Collaborative (GPC) is a network of 12 leading medical centers in eight states committed to a shared vision of improving healthcare delivery through ongoing learning, adoption of evidence-based practices, and active research dissemination. GPC builds on strong research programs at individual sites, existing community engagement and informatics infrastructures and data warehouses
The Consortium of Rural States (CORES) was formed to facilitate collaborative and disciplined efforts that will produce new opportunities for advancing translational research. The Collaborative comprises Arkansas, Kansas, New Mexico and Utah, states that share common health care challenges, including significant rural populations. Each state is served by a single Clinical and Translational
- -University Of UtahThe Utah CCTS is hosting their second annual Research Trainee Symposium on November 7, 2019. This all-day symposium, which will be held at the Alumni House on the Campus of the University of Utah, will include oral and poster presentations by trainees, as well as a keynote address from an invited guest with a distinguished career in mentorship. The day will end in a celebratory dinner.
- University Of Utah
The Utah CCTS Cellular Translational Research Core (CTRC) was officially launched in 2016 as a part of the Utah CCTS Precision Medicine program. The main CTRC priorities have been 1) to provide support and services for the investigators interested in stem cell research; 2) establish new services related to the generation of CRISPR/Cas9-edited human stem cell lines; and 3) educate the community on