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July 22, 2022Clinical research professionals (CRP) are a vital part of the clinical and translational science workforce. However, there are multiple barriers to recruiting, training, and retaining these vital workers at academic medical centers, compounded by the disruption of the COVID-19 pandemic, resulting in a frustratingly quick turnover rate at these institutions. In September 2020, the Institute of
August 30, 2022CTSA Program hubs offer a wide range of services, from bioinformatics to recruitment support, to help investigators across disciplines design, implement and report their research more rigorously and efficiently. In 2018, Julie T. Elworth, Ph.D., director of evaluation at the University of Washington Institute of Translational Health Sciences (ITHS), realized that more than 75 percent of
September 21, 2022Dr. LaQuita Jones, CCTST KL2 Scholar graduate and assistant professor at Cincinnati Children's Hospital Medical Center, is featured as St. Baldrick's Scholar during Childhood Cancer Awareness Month. Video can be viewed here: https://twitter.com/StBaldricks/status/1570884378653491200 About Dr. Jones's Research: Acute myeloid leukemia (AML) is a difficult to treat cancer that is associated with
September 21, 2022Two projects have been given the green light to explore new technology and practices that have the potential to save lives and reduce health care inequity through the Irving Institute for Clinical and Translational Research’s Strategic Priorities Pilot Award – Learning Health System. A collaboration with the Columbia University Learning Health System initiative, the Columbia University Irving
September 21, 2022PENN STATE CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE PROGRAM PROVIDES STUDENTS WITH KNOWLEDGE AND SKILLS ESSENTIAL FOR CONDUCTING INTERDISCIPLINARY TRANSLATIONAL RESEARCH Graduate students with varied research interests – including the impact of housing insecurity on biological health, the role of probiotic consumption on inflammation and traumatic brain injury recovery – have started a
September 20, 2022Jennifer L. Vincenzo, Ph.D., MPH, PT, recently became the first University of Arkansas for Medical Sciences (UAMS) researcher to receive the national Paul B. Beeson Emerging Leaders Career Development Award in Aging, which comes with $1 million over five years. The award will support Vincenzo’s work implementing a falls prevention strategy as a standard of care for all older adults attending
September 19, 2022COMMUNITY STAKEHOLDERS SAY BETTER TREATMENT GUIDANCE COULD BE USEFUL FOR PATIENTS Penn State faculty are joining clinical researchers from across the country to study treatment approaches for acute rhinosinusitis, also called “sinusitis.” The condition is an inflammation of the nose and sinus passages most often caused by a viral or bacterial infection that affects one in seven U.S. adults each
September 16, 2022As we head into our third fall of the COVID pandemic, nearly one-third of the U.S. population is still not fully vaccinated, likely due in part to vaccine hesitancy. An Arts and Medicine article recently published in JAMA describes a UR CTSI-supported program that turned to improv theater for help addressing vaccine hesitancy. The program, called the Theater for Vaccine Hesitancy, combined improv
September 16, 2022Penn State researchers with varied research interests, including identifying mental health risk factors, improving quality of life for aging adults and combatting chronic disease in vulnerable populations, have embarked upon a training program in clinical and translational sciences. The Mentored Career Development KL2 Program is a two- to three-year opportunity offered by Penn State Clinical and
September 15, 2022Georgia CTSA investigator Suresh S. Ramalingam, MD, is the Executive Director at Winship and leads the growth and development of cancer research, clinical care, and education. A study led by Winship Cancer Institute of Emory University offers new insight into what causes resistance to the non-small cell lung cancer (NSCLC) medication osimertinib that may prove valuable in developing more effective
September 14, 2022Black Americans are twice as likely to experience a stroke and face worse outcomes compared to their white peers. But a new project supported by the University of Minnesota CTSA is working to change that. The community-engaged research study started with focus groups and is now turning its attention to training “stroke champions” who can educate the rest of their community. Niloufar Hadidi, PhD
September 14, 2022University of Arkansas for Medical Sciences (UAMS)-affiliated researchers who have received Translational Research Institute (TRI) support submitted 77 research manuscripts as part of the Summer 2022 Writing Challenge, TRI Director Laura James, M.D., announced at an Ice Cream Social celebration to recognize the contributing researchers. Held jointly at UAMS campuses in Little Rock and Northwest
September 09, 2022Mothers Leading Science was recently adopted by the University of Pittsburgh, making it the first institution outside the University of Minnesota to implement the program as a sister site. Established by the Clinical and Translational Science Institute at the University of Minnesota in 2018, Mothers Leading Science is a yearlong career development program for research-intensive faculty in the
September 08, 2022Sana Syed, MD, MSCR, MSDS, an associate professor in the School of Medicine’s Department of Pediatrics, was recently awarded an R01 grant from the NIH providing $3,522,906 in funding over the next 5 year to investigate metabolic pathways associated with Crohn’s disease in children.
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September 08, 2022
How might insomnia-fighting interventions delivered over the internet help slow older patients’ descent into dementias such as Alzheimer’s disease? With a $1.22 million, five-year grant from the National Institutes of Health, University of Virginia assistant professor of nursing Meghan Mattos will investigate the connections between poor sleep, cognitive decline and the potential brain-saving
September 06, 2022Nine UMass undergraduate students were recognized for their summer research internship work as part of an inaugural multi-campus collaboration. This internship program was developed to give students from the UMass Amherst School of Public Health & Health Sciences and the UMass Lowell Zuckerberg College of Health Sciences the experience in clinical research, and to provide insight into the rewards
August 30, 2022The NCATS Translational Science Principles are a new resource that summarizes key approaches for accelerating progress along the translational pipeline toward solutions to improve human health. The principles complement the 2011 CTSA Education Core Competency Work Group’s 14 Core Competencies in Clinical and Translational Research, while drawing the focus to knowledge, skills, and attitudes
August 26, 2022The NCATS-funded Evolve to Next-Gen ACT (ENACT) is a collaborative research platform that will enable investigators at CTSA hubs to conduct EHR research on any disease or condition from their desktop. Using de-identified data from EHRs for >142 million patients at 57 hubs, ENACT will also allow data scientists to develop and test EHR-based research tools. ENACT is the next iteration of the ACT
August 25, 2022An excerpt from David Ho and Rita Charon Narrative Interview 2022: Overcoming translational science barriers. David’s reflections illuminate potential barriers to progress in translational science—the grip of dogma and the challenge of living up to science’s ethical mission: The grip of dogma: In the early days of HIV/AIDS research, David suffered persistent criticism from colleagues and superiors
August 25, 2022On Thursday, 4 August 2022, a public health emergency was declared for the contagious disease known as monkeypox. Do you know how to access tecovirimat (brand name TPOXX® from Siga Techologies) an anti-viral to treat patients that have tested positive for monkeypox? Several players are involved in making this happen! TPOXX® is approved for the treatment of human smallpox which is caused by the
August 25, 2022A research study of African Americans with cardiovascular disease suggests religious practices and spirituality may contribute to heart health. The study's authors assert that recognizing the importance of religious practices and spirituality in the lives and health of African Americans may be key to improving patient care and reducing heart health disparities in African American communities
August 25, 2022Mayo Clinic announced today that its Center for Clinical and Translational Science has successfully renewed funding for its research grant from the National Institutes of Health National Center for Advancing Translational Sciences for five more years. The funding award, totaling $48.2 million, is one of Mayo’s largest NIH grants, supporting research and education across the institution at that
August 22, 2022The social determinants of health — the conditions in which a person lives, learns, works, and plays — account for 80 percent of health outcomes, but they’re almost never used in medical care. “So much affects health outcomes beyond what happens at a medical facility, such as education, access to transportation, financial stability, and more,” says David Haynes, PhD, an Assistant Professor in the
August 19, 2022CTSI KL2 scholar Carolyn Bramante, MD, MPH, led the nation’s first study on whether metformin, fluvoxamine, and ivermectin, or their combinations could serve as possible treatments to prevent ER visits or hospitalization, as well as Long-COVID. Yesterday, the New England Journal of Medicine published the results of the clinical trial. “Our trial suggests that metformin may reduce the likelihood of
August 19, 2022Over nearly two decades, more and more patients have chosen stereotactic body radiation therapy (SBRT) as an alternative to surgery for certain kinds of early-stage lung cancer. SBRT deploys innovative techniques to target and deliver high levels of focused radiation doses to tumors. Even so, surgery remains the standard of care. So, why are more patients picking this non-surgical method? Are
August 19, 2022If untreated, chronic foot wounds threaten the limbs and lives of diabetic patients. High blood sugar associated with diabetes can lead to complications in sensation and circulation limit blood circulation needed to fight off foot infections, leading to diabetic foot ulcers. Many wounds become infected, leading to amputation. More than half of diabetic patients who get a below-the-knee amputation
August 19, 2022Applications for the new cohort of SC-CTSI KL2 scholars is due on September 16, 2022. For more details on how to apply, please visit this website: https://sc-ctsi.org/training-education/mentored-career-development-in-clinical-and-translational-science-program We sat down (virtually!) with Xenos Mason, MD, a recipient of the SC CTSI Mentored Career Development in Clinical and Translational Science
August 17, 2022Hongfang Liu, Ph.D., the Richard Emslander Professor of Biomedical Informatics in Mayo Clinic College of Medicine and Science, has a full plate. She specializes in applications of artificial intelligence (AI) in medical science and health care — an area of research that's booming at Mayo Clinic and around the world. Dr. Liu is director of Biomedical Informatics in Mayo Clinic's Center for Clinical
August 11, 2022Newly awarded NIH NIDDK R25 grant establishes Washington University as a coordinating center for the Short-Term Research Experience Program to Unlock Potential (STEP-UP)
August 11, 2022Patients previously hospitalized with COVID-19 had a 45% higher risk of heart failure than other hospitalized patients, according to the first national study of its kind, which was co-authored by a University of Arkansas for Medical Sciences (UAMS) researcher. Lead author Husam M. Salah, M.D., at UAMS said the findings reported in Nature Communications also revealed an even higher risk of heart