News

A discussion with Andrea Califano and narrative medicine writer, Rita Charon: Art and science unfold in time as chronological sightings overturn until-then received knowledge—from the epic to the novel, from classical portraiture to cubism, from before Copernicus to after Copernicus. Art and science unfold in space as discoverers choose a scale and a scope—from parole to langue, from harmony to

The CCTSI responded to the pandemic by issuing a rapid-release RFA to address COVID-19. CCTSI leaders called it the COVID-19-Rapid Research Pilot Program. They released the RFA on Monday evening, March 30 and closed the application process just four days later. This new pilot grant program supported the development of novel diagnostic and treatment methods and innovative technologies related to

Adit Ginde, MD, and the Colorado Clinical Translational Sciences Institute team are spreading the word about monoclonal antibody treatment for COVID-19. As the COVID-19 pandemic continues to lurk in many communities, aided by vaccine hesitancy and the emergence of disease mutations like the Delta variant, physicians are still looking for effective ways to treat those who test positive for the

LITTLE ROCK — A statewide COVID-19 antibody study led by the University of Arkansas for Medical Sciences (UAMS) found that by the end of 2020, 7.4% of Arkansans had antibodies to the virus, but there were wide disparities among racial and ethnic groups. UAMS researchers released their findings this week to a public database, medRxiv (med archive). The study included analysis of more than 7,500

When thinking about diversity and inclusion, consider music. A symphony orchestra is comprised of the strings, the woodwinds, the brass and percussion. Without one, you lose the depth of sound. Without them all, you lose the genius of Beethoven or Mozart. In medicine and clinical research, innovation and widespread impact cannot be achieved unless representation from every section of culture and

The CTSA program was developed to accelerate new treatments from the lab to patients, enabled to a large extent by patients participating in and benefiting from clinical trials. Clinical trials provide that needed bridge from human subjects to hypotheses to treatments that can directly benefit human health. And, never has this connection been more critical than amid the global COVID-19 pandemic

No champion race car driver can win without a dedicated pit crew. The same is true in medical research. Thanks to their “pit crew” Mayo Clinic researchers were able to repurpose an experimental therapy, called lenzilumab, for patients with COVID-19 pneumonia, and from there into a phase three clinical trial — all in about one year. "I think we’ve accomplished in this year what normally would take

With funding from CTSI, University of Minnesota researchers worked with local Indigenous community partners to develop evidence-based and culturally appropriate COVID-19 resources, creating three distinct fact sheets on staying healthy and staying connected during the pandemic. The project, “Helping Indigenous communities stay connected in light of COVID-19,” was conducted by the Memory Keepers

The Foundations of Biomedical Data Science at the University of Virginia hosted its fifth annual Biomedical Data Science Innovation Lab (BDSIL): Challenges in Brain Analytics and Data Integration on June 21-25, 2021. The BDSIL is an intensive program partially sponsored by iTHRIV and NIH Grant #R25GM139080 that has virtual and in-person components designed to foster the development of

“It was surreal, it seemed like this day would never come at times,” says Jacqueline Zayas, of the many hours spent in the lab and classroom working toward her M.D., and Ph.D. For as long as she could remember, Dr. Zayas, who hails from Miami, Fla., says she would tell her family that she wanted to become a doctor. The M.D. - Ph.D. program, offered by the Mayo Clinic Center for Clinical and

Sample code templates developed by the iTHRIV CTSA team enable rapid analytics onboarding to the National COVID Cohort Collaborative (N3C) Data Enclave. The National COVID Cohort Collaborative (N3C) Data Enclave is an analytics platform containing clinical data from electronic health records from over 55 sites around the country. This data from SARS-CoV-2 positive patients (and matched controls)

Vitamin C, an essential dietary nutrient for humans, has been touted for its immune boosting properties for more than half a century. More recently, research has revealed its greater potential as a treatment for blood cancers. In her ongoing research, Miami CTSI Pilot Award recipient and Principal Investigator Luisa Cimmino, Ph.D., explores the potential of Vitamin C to combat blood cancers such as leukemia.

The first two COVID-19 vaccines authorized for emergency use by the Food and Drug Administration (FDA) employed a technology that had never before been used in FDA-approved vaccines. Both vaccines performed well in clinical trials, and both have been widely credited with reducing disease, but concerns remain over how long immunity induced by the new vaccine technology will last. Now, a study from

Amy Lasek, a former UIC Center for Clinical and Translational Science pilot grant awardee (2018-2020) and researcher at UIC’s Center for Alcohol Research in Epigenetics, was published in the journal Translational Psychiatry. The study, “Transcriptomics identifies STAT3 as a key regulator of hippocampal gene expression and anhedonia during withdrawal from chronic alcohol exposure,” builds on her

As it turns out, they will. A team of researchers that has been evaluating the Washington University Institute for Clinical and Translational Sciences (ICTS) since 2010 has released new findings. They suggest that CTSA member researchers who engaged with dedicated ICTS infrastructure and resources increased their research productivity; members who took advantage of ICTS services were more likely