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The Foundations of Biomedical Data Science at the University of Virginia hosted its fifth annual Biomedical Data Science Innovation Lab (BDSIL): Challenges in Brain Analytics and Data Integration on June 21-25, 2021. The BDSIL is an intensive program partially sponsored by iTHRIV and NIH Grant #R25GM139080 that has virtual and in-person components designed to foster the development of multidisciplinary teams.