Scientists Re-Create Brain Neurons to Study Obesity and Personalize Treatment

Scientists have re-created brain neurons of obese patients using "disease in a dish" technology, offering a new method to study the brain's role in obesity and possibly help tailor treatments to specific individuals.

The technology is the first step in developing a great platform that potentially could be used to evaluate the effects of experimental therapeutics on specific patients, according to Dhruv Sareen, PhD, assistant professor at Cedars-Sinai Medical Center in Los Angeles, a partner institutuion in the UCLA CTSI.  "Ultimately," Sareen said, "we are paving the way for personalized medicine, in which drugs could be customized for obese patients with different genetic backgrounds and disease statuses.”