CTSA Program Publications
The publications shown on this website are not inclusive all of the publications generated by the CTSA Program and its funded institutions. Publications shown below are a curated list of more recent publications and/or publications that have been submitted to CLIC as a product of NCATS related information, CTSA Program group initiative (i.e. Steering Committee, EC or Working Group), or CLIC funded initiative (Un-Meeting or Synergy Paper). Only publications that have NCATS and/or a CTSA Program funded institution acknowledged will be considered for display on this website. Should you wish to share an applicable publication please Contact Us.
Combating Structural Inequities - Diversity, Equity, and Inclusion in Clinical and Translational ResearchThe New England Journal of Medicine
If the clinical and translational research enterprise is to help resolve health crises and ensure that all people in the United States have the opportunity to live healthy lives, it must shift paradigms and begin to center equity, diversity, and inclusion in its work.
Barriers and Solutions to Developing and Maintaining Research Networks during a Pandemic: An example from the iELEVATE Perinatal NetworkJournal of Clinical and Translational Science
Clinical and Translational Science Award T32/TL1 Training Programs: Program Goals and Mentorship PracticesJournal of Clinical and Translational Science
A national survey characterized training and career development for translational researchers through Clinical and Translational Science Award (CTSA) T32/TL1 programs. This report summarizes program goals, trainee characteristics, and mentorship practices.
Understanding enterprise data warehouses to support clinical and translational research: enterprise information technology relationships, data governance, workforce, and cloud computingJournal of the American Medical Informatics Association
Among National Institutes of Health Clinical and Translational Science Award (CTSA) hubs, effective approaches for enterprise data warehouses for research (EDW4R) development, maintenance, and sustainability remain unclear. The goal of this qualitative study was to understand CTSA EDW4R operations within the broader contexts of academic medical centers and technology.
Artificial intelligence in Clinical and Translational Science: Successes, Challenges and OpportunitiesAmerican Society for Clinical Pharmacology & Therapeutics Clinical and Translational Science Journal
Artificial intelligence (AI) is transforming many domains, including finance, agriculture, defense, and biomedicine. In this paper, we focus on the role of AI in clinical and translational research (CTR), including preclinical research (T1), clinical research (T2), clinical implementation (T3), and public (or population) health (T4).
- Bioactive materials
Infection in hard tissue regeneration is a clinically-relevant challenge. Development of scaffolds with dual function for promoting bone/dental tissue growth and preventing bacterial infections is a critical need in the field.
Integrating dissemination and implementation sciences within Clinical and Translational Science Award programs to advance translational research: Recommendations to national and local leadersJournal of Clinical and Translational Science
The National Center for Advancing Translational Sciences (NCATS) has defined translation as the process of turning observations into interventions that are adopted, sustained, and improve health. Translation must attend to research and community systems and context at multiple levels, and to key stakeholders.
Teaching for implementation: A framework for building implementation research and practice capacity within the translational science workforceJournal of Clinical and Translational Science
Implementation science offers a compelling value proposition to translational science. As such, many translational science stakeholders are seeking to recruit, teach, and train an implementation science workforce. The type of workforce that will make implementation happen consists of both implementation researchers and practitioners, yet little guidance exists on how to train such a workforce.
Cognitive Performance Scores for the Pediatric Automated Neuropsychological Assessment Metrics in Childhood-Onset Systemic Lupus ErythematosusArthritis care & research
To develop and initially validate a global cognitive performance score (CPS) for the Pediatric Automated Neuropsychological Assessment Metrics (PedANAM) to serve as a screening tool of cognition in childhood lupus.
Background and Aims In patients with chronic liver diseases (CLD) with or without cirrhosis, existing data on the risk of adverse outcomes with SARS-CoV-2 infection have been mixed or have limited generalizability.
Outcomes of COVID-19 in Patients With Cancer: Report From the National COVID Cohort Collaborative (N3C)Journal of Clinical Oncology
Bulk volume susceptibility difference between deoxyhemoglobin and oxyhemoglobin for HbA and HbS: A comparative studyMagnetic resonance in medicine
Sickle cell anemia is a blood disorder that alters the morphology and the oxygen affinity of the red blood cells. Cerebral oxygen extraction fraction measurements using quantitative BOLD contrast have been used for assessing inadequate oxygen delivery and the subsequent risk of ischemic stroke in sickle cell anemia.
The association between psychological functioning and social support and social constraint after cancer diagnosis: a 30-day daily diary studyJournal of behavioral medicine
This study evaluated one positive and one negative aspect of social functioning (social support and social constraint, respectively) to increase understanding of its relation to psychological functioning (distress and wellbeing) after cancer diagnosis. Participants in this longitudinal study were recently diagnosed, predominately late stage, first primary cancer survivors (n = 48).
Unexpected case of cryptococcal meningoencephalitis in a patient with long-standing well-controlled HIV infectionMedical mycology case reports
Cryptococcal meningoencephalitis (CM) classically occurs in individuals with advanced HIV infection, solid organ transplants, or other immunocompromising conditions. We report a case of fatal CM in a 78-year-old woman with well-controlled HIV infection who had delayed diagnosis, persistently elevated intracranial pressure and pleocytosis of the cerebrospinal fluid.
- Clinical and Translational Science
The mission of translational science is to bring predictivity and efficiency to the development and dissemination of interventions that improve human health. Ten years ago this year, the National Center for Advancing Translational Sciences was founded to embody, conduct, and support this new discipline.