Innovation
March 14, 2023Drugs known as PARP-1 inhibitors have emerged as an important but limited treatment option for certain cancers. Now, scientists at Oregon Health & Science University (OHSU) have uncovered a new class of PARP-1 inhibitors with unique and powerful anticancer properties that could make them more widely effective. Dr. Michael Cohen’s lab has discovered an exciting candidate for an anti-cancer drug — a
February 02, 2023Researchers at Oregon Health and Science University (OHSU), including David Sheridan, MD, Steven Baker, PhD, and Bonnie Nagel, PhD, are partnering with the semiconductor company, Analog Devices, Inc., to develop wearable smartwatch technology that they hope will provide early detection for individuals, especially adolescents, with depression and suicidality. This idea was originally conceived of
February 02, 2023In collaboration with OHSU Innovates, the Oregon Clinical and Translational Research Institute (OCTRI) announced two new funded projects for the 2022 device, diagnostics, and software track of the Biomedical Innovation Program. This program supports and accelerates creative, interdisciplinary device, diagnostic, and software development research at OHSU. Funded projects and awardees for 2022
-University Of Alabama At BirminghamFind out via the online I-Corps@NCATS National Bootcamp. Based on the National Science Foundation’s Innovation Corps (I-Corps™) program, the premier federally-funded innovation and commercialization training program in the U.S., I-Corps@NCATS provides biomedical scientists and clinicians with a new approach to accelerate the translation of discoveries from the lab to clinical practice. WHO: Teams
January 04, 20232023 BDSIL: Data Science and the Public Health Consequences of the COVID-19 Pandemic June 26-30, 2023 • Kenmore, Washington Applications due January 29, 2023 at 11:59 PM ET Join us for the 2023 BDSIL: a unique hybrid program consisting of online team-building activities and a series of scientific presentations that lead-up to an all-expenses-paid, 5-day in-person intensive workshop at The Lodge at
November 07, 2022Oregon's CTSA hub, the Oregon Clinical and Translational Research Institute (OCTRI), accelerates innovation at Oregon Health and Science Univeristy (OHSU) with pilot funding, project management, and entrepreneur education. OCTRI's Biomedical Innovation Program (BIP), which includes pilot funds and project management support, was featured in the 2022 OHSU Innovates Impact Report. OCTRI is
-University of VirginiaAPPLICATIONS DUE January 8th The global COVID-19 pandemic over the past two years has upset our lives in ways unimaginable before we took to wearing masks, isolating at home, and avoiding contact with family, friends, and colleagues. We are only now, just contending with the secondary effects of COVID exposures – so-called ‘long-haul COVID’ – but also the effects of deferred regular health check
Yale UniversityBidirectional Partnerships: Moving at the Speed of Trust to Speed Innovation: Yale School of Medicine (YSM) and its Yale Center for Clinical Investigation (YCCI), the administrative home of the Yale CTSA, has had great success advancing health and research equity through the science of translation and collaboration, including: Addressing community health equity and capacity building with the
-Vanderbilt University Medical CenterDigital technology can enable trial participation via an internet portal or smartphone app, eConsent, data collection directly via wearables and smartphones, ecologic momentary assessment, and other trial innovations. The Eureka Research Platform, a digital platform funded by NIH and housed at UCSF, supports digital trials and prospective data collection for funded researchers across the US
August 09, 2022OHSU* Senior Director for Collaboration & Entrepreneurship and OCTRI** Director of Innovation Programs and Awards, Aditi Martin, PhD, co-authored an article for Oregon Business magazine about cultivating diversity and inclusion in business and innovation environments, based upon her work at OCTRI and OHSU. She co-wrote the op-ed with Graciela Gomez Cowger, JD, CEO of Schwabe, Williamson, and Wyatt
-University Of RochesterThe University of Rochester Clinical and Translational Science Institute and Ain Center for Entrepreneurship and Innovation are hosting an I-Corps@NCATS Regional Short Course this fall, specifically designed to provide biomedical scientists, clinician scientists, and engineers with a new approach to accelerate the translation of their discoveries from the lab to clinical practice. This program
July 15, 2022In collaboration with OHSU Innovates, the Oregon Clinical and Translational Research Institute (OCTRI) announced two new funded projects for the 2022 drug discovery track of the Biomedical Innovation Program. This program supports drug discovery platforms and early-stage therapeutic technology projects, including validation of drug targets and development of small molecules, antibodies, vaccines
June 13, 2022Researchers are working to better prepare for the next pandemic. One of those researchers is Kevin Messacar, MD, PhD, an infectious disease expert and physician at Children’s Hospital Colorado and associate professor at the University of Colorado Anschutz Medical Campus. Messacar is leading an innovative, nationwide pilot study focusing on enterovirus D68, a virus that is linked to a rare polio
April 27, 2022Alicia Agnoli, assistant professor of family and community medicine at UC Davis School of Medicine, was recently honored with a 2022 Top Ten Clinical Research Achievement Award by the Clinical Research Forum (CR Forum). At a ceremony held in Chicago, Agnoli was also presented with the Distinguished Clinical Research Achievement Award for creativity, innovation, and novel approach that demonstrated
April 06, 2022In the recent Journal of Clinical and Translational Sciences (JCTS) thematic issue on Entrepreneurship and Innovation, institutions showcase their experience, approaches, and findings in the area of innovation and academic entrepreneurship. Translating innovations into improved human health reflects NCATS’ mission and the goals of the CTSA Program. Through the CTSA Program, hubs work tirelessly to
University Of Miami School Of MedicineThe dissemination of the I-Corps@NCATS program has accelerated the development and commercialization of breakthrough innovations in medical research across U. Miami and the CTSA partner hubs. Taking the lessons from the “I-Corps at the CTSA Train-The-Trainer pilot initiative” in 2017, nine participants developed the I-Corps@NCATS program with support from a CTSA Administrative Supplement to
Trial Innovation NetworkDaniel Benjamin, MD, PhD, MPH1; Gordon R. Bernard, MD2; J. Michael Dean, MD, MBA3; Daniel E. Ford, MD, MPH4; Daniel Hanley, MD4; Paul A. Harris, PhD, FACMI2; Harry Selker, MD, MSPH5; Consuelo H. Wilkins, MD, MSCI2 1Duke Clinical Research Institute, 2Vanderbilt Institute for Clinical and Translational Research, 3University of Utah, 4Johns Hopkins University, 5Tufts University ABSTRACT: The Trial
University Of North Carolina Chapel HillTrue innovation depends on identifying the right problem to solve. To streamline the process of identifying opportunities for innovation, FastTraCS has developed a virtual, scalable approach to rapidly identifying impactful clinical problems—creating a foundation for unmet need definition, validation and new product development. This approach eliminates the need for upfront clinical shadowing/
-NCATSHarnessing NCATS SBIR/STTR Funding to Support Commercialization for Innovations in Translational Sciences Wednesday, October 27th, 2021, 1:00 – 2:00 p.m. ET Join Medical University of South Carolina (MUSC) in collaboration with the National Center for Advancing Translational Sciences (NCATS) on Wednesday, October 27, 2021, for a webinar to learn about the Small Business Innovation Research and
September 27, 2021OHSU startup, Inherent Targeting, is among the Pacific Northwest-based startups selected to present at the Pacific Northwest Startup Showcase & Social on Tuesday, October 12 from 10am-12pm. Inherent Targeting improves surgical outcomes with high contrast, nerve-specific fluorescent dyes that help surgeons visualize buried nerves and distinguish them from surrounding tissue. This reduces patient
September 02, 2021In 2020, the Oregon Clinical & Translational Research Institute (OCTRI) awarded Jessica Grant, an OHSU speech therapist, and David Sheridan, MD, an OCTRI Scholar and OHSU associate professor of emergency medicine, a Biomedical Innovation Program award for their device called the Koala Kushion. This week, the duo was interviewed for OHSU's Innovator Spotlight series. Read more about their progress
-University Of North Carolina Chapel HillThe Catalyze Program, established by NHLBI and run by Research Triangle Institute (RTI) International, transforms basic science discoveries into viable therapeutics, devices, and diagnostics. While the actual Catalyze Program is focused on products for heart, lung, blood, and sleep disorders, the information presented in these monthly seminars is foundational knowledge about product development
July 26, 2021In collaboration with the Technology Transfer and Collaborations & Entrepreneurship offices at Oregon Health & Science University (OHSU), the Oregon Clinical and Translational Research Institute (OCTRI) announced three new funded projects for the 2021 drug discovery track of the Biomedical Innovation Program. This program supports drug discovery platforms and early-stage therapeutic technology
July 23, 2021The CCTSI responded to the pandemic by issuing a rapid-release RFA to address COVID-19. CCTSI leaders called it the COVID-19-Rapid Research Pilot Program. They released the RFA on Monday evening, March 30 and closed the application process just four days later. This new pilot grant program supported the development of novel diagnostic and treatment methods and innovative technologies related to
- Journal of Clinical and Translational Science
The recipients of NIH Clinical and Translational Science Awards (CTSA) have worked for over a decade to build informatics infrastructure in support of clinical and translational research.
March 08, 2021OCTRI Scholar Dr. David Sheridan (left) and Dr. Matthew Hansen (right), both OHSU Emergency Medicine physicians, were awarded OCTRI Biomedical Innovation Program (BIP) funding and project support in 2018 to develop a new bedside technology for quickly detecting sepsis using an accurate and objective measure of capillary refill time (CRT). In the last 3 years, Drs. Sheridan and Hansen leveraged
January 21, 2021The VCU Wright Center and its researchers were featured in an MCV Foundation magazine article about how the university and health system adapted to the COVID-19 pandemic last year. Petri dishes and slides were frozen. Study plans were amended. Some research pivoted. And more than 50 new projects at Virginia Commonwealth University emerged to combat the new virus on multiple fronts. Research
December 22, 2020In collaboration with the Technology Transfer and Collaborations & Entrepreneurship offices at Oregon Health & Science University (OHSU), the Oregon Clinical and Translational Research Institute (OCTRI) announced four new funded projects for the 2021 device and diagnostics track of the Biomedical Innovation Program. This program cultivates, evaluates, and funds promising translational projects
University Of California DavisThe UC Davis CTSC applied the CTSA program goals to assist the division of pulmonary and sleep medicine with the recruitment, examination, and treatment of a diverse array of participants into an industry-funded COVID-19 vaccine trial. The project encompassed all five of the CTSA program goals and resulted in a robust study population. The first 80 subjects were recruited, screened, and scheduled
August 07, 2020The Oregon Clinical & Translational Clinical Research Institute (OCTRI) at Oregon Health & Science University (OHSU) funded three projects for their 2020 Biomedical Innovation Program drug discovery track. The funded research covers pancreatic cancer, prostate cancer, and SARS-CoV-2. This category of funding supports drug discovery platforms and early-stage therapeutic technology projects