clinical trials
July 22, 2021The CTSA program was developed to accelerate new treatments from the lab to patients, enabled to a large extent by patients participating in and benefiting from clinical trials. Clinical trials provide that needed bridge from human subjects to hypotheses to treatments that can directly benefit human health. And, never has this connection been more critical than amid the global COVID-19 pandemic
July 20, 2021No champion race car driver can win without a dedicated pit crew. The same is true in medical research. Thanks to their “pit crew” Mayo Clinic researchers were able to repurpose an experimental therapy, called lenzilumab, for patients with COVID-19 pneumonia, and from there into a phase three clinical trial — all in about one year. "I think we’ve accomplished in this year what normally would take
VCU Wright Center: COVID-19 survivor and ACTIV-1 trials participant looks forward to traveling again
July 06, 2021When Linda Thompson retired from the Virginia Department of Transportation in 2019, she started a new job the next day — getting fit. “My new job was going to American Family Fitness and getting in the pool and doing water aerobics,” said Thompson, 72. “I was really in bad shape when I retired. So it was time for me to take care of Linda.” Thompson lost 60 pounds over the next year. The exercise
-State University Of New York At BuffaloJoin the University at Buffalo Clinical and Translational Science Institute (CTSI) and the Medical University of South Carolina (MUSC) South Carolina Clinical and Translational Research (SCTR) from 10:00 a.m. to 5:00 p.m. EST on Tuesday, November 9, for a virtual workshop exploring remote clinical trials. Goals of the workshop are to: understand the strengths, challenges, and opportunities for
June 24, 2021Among the Southern California Clinical and Translational Science Institute's most important services to the research community are their support and tools (https://bit.ly/3qmjIb9) designed to help investigators overcome the all-too-familiar hurdle of clinical study recruitment. As a result, few people are more cognizant of the importance of participation in clinical research than the personnel of
June 24, 2021Among the Southern California Clinical and Translational Science Institute's most important services to the research community are their support and tools (https://bit.ly/3qmjIb9) designed to help investigators overcome the all-too-familiar hurdle of clinical study recruitment. As a result, few people are more cognizant of the importance of participation in clinical research than the personnel of
-University Of Miami School Of MedicineOn July 8 from 1 to 2 p.m., as The Miami Clinical and Translational Science Institute (CTSI) will host four Principal Investigators from the University of Miami for a virtual presentation to discuss the challenges and barriers as well as the strategies and best practices for recruiting underrepresented minorities into their various clinical research studies.
June 22, 2021Clinical trials help researchers discover and apply critical advances in patient care. Clinical trials follow rigorous scientific processes that usually take many years to complete. However, during the COVID-19 pandemic, people have been able to see and experience clinical trials operating on fast-forward. And a lot of people are wondering, "How do clinical trials work?" In this Q&A, the Mayo
June 11, 2021Dr. Elizabeth Ofili, a principal investigator at the Georgia CTSA, gives a 4x4 presentation at the Un-Meeting. Researchers across the country gathered virtually last month to discuss outreach to community hospitals for recruitment and enrollment into clinical trials at the CLIC-hosted Un-Meeting “Exploring the Inclusion of Community Hospitals in Clinical Research.” The topic, chosen by the
May 20, 2021Paul “Pee-J” Beverly doesn’t remember being airlifted to VCU Health from Lexington, Va., last fall. In fact, he doesn’t remember much of his COVID-19 experience at all. But his girlfriend, Angela Griffin, does. “It was one of the scariest things I’ve ever been through,” she said. “Not being able to see him, barely being able to talk to him. And knowing it was touch and go. They pretty much
-Virginia Commonwealth UniversityAfter the last year facing a global pandemic of a novel virus, it’s never been clearer that clinical trials save and improve lives. Thanks to clinical trials, we now have vaccines and treatments for COVID-19 and hope for a better tomorrow. Join a virtual discussion with VCU Wright Center leader and hepatologist Arun Sanyal and VCU Massey Cancer Center medical oncologist Sarah Gordon. Gordon leads
University Of Southern CaliforniaCOVID-19 has thrown a wrench into research conduct, forcing hospitals and universities to transfer their research plans, data collection procedures, survey dissemination processes, and participant engagement methods quickly and nimbly to online venues. In addition, the state of research operations has changed dramatically due to the pandemic. This guide provides key considerations for ensuring
- Journal of Clinical and Translational Science
Clinical trials are a fundamental tool in evaluating the safety and efficacy of new drugs, medical devices, and health system interventions. Clinical trial visits generally involve eligibility assessment, enrollment, intervention administration, data collection, and follow-up, with many of these steps performed during face-to-face visits between participants and the investigative team.
April 09, 2021Kate Marusina, director of the CTSC Clinical Trials Office, oversees a team that provides support for clinical trials at UC Davis. UC Davis conducts more than 2,000 research studies at any given time, including basic science, translational, and clinical trial research — all with the goal of bringing new, effective, and safe treatments to patients more quickly. In this brief interview conducted by
April 07, 2021Social distancing and lockdowns may have reduced the spread of COVID-19, but researchers from Penn State College of Medicine also report those actions may have affected clinical researchers’ ability to finish trials. Study completion rates dropped worldwide between 13% and 23%, depending on the type of research sponsor and geographic location, between April and October 2020. Researchers previously
-Wake Forest University Health SciencesWake Forest School of Medicine | Atrium Health Research Symposium: COVID-19 Research Updates Hosted by: John Walton Sanders III, MD, MPH Section Chief, Infectious Diseases, Wake Forest School of Medicine Michael Gibbs, MD, FACEP, FAAEM Chair, Emergency Medicine & Interim Vice President of Research, Atrium Health Sponsored by the Wake Forest CTSI Team Science Program Click here to learn more about
-Vanderbilt University Medical CenterClinical research must be modernized. There are increasing demands to have more rapid innovation in order to develop novel treatments more quickly and cost effectively. The challenges that COVID add to the landscape of clinical trials also brings potential for new pathways of clinical trial innovation. Join this discussion to hear about the potential factors driving the decision to use an
Tufts University BostonClinical trial feasibility – it’s a standard part of recruitment planning and essential for predicting enrollment success. Yet so often it’s easy to get wrong, putting timelines and budget at risk. And whether that’s because there’s too great a focus on quantitative factors – such as volume of patients or number of competing studies – it’s clear that study sponsors and sites can benefit from an
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Tufts University Boston
What is stakeholder and community engagement (SCE), and why is it important? Learn the benefits, strategies, and methods at Stakeholder Engagement in Patient-Centered Comparative Effectiveness Research. This seminar, taught by Thomas Concannon, PhD, Tufts CTSI’s Director of Stakeholder and Community Engagement and Assistant Director of Comparative Effectiveness Research, will review previous
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Tufts University Boston
What are successful strategies for recruiting and retaining patient participants in research? We know you know. Study after study shows that recruiting and retaining study participants is one of the weakest links in clinical research. Energize yourself with this interactive course to learn how to adopt a patient-centric mindset for clinical research. Understanding the principles and standards that
-University Of Southern CaliforniaIssues to be addressed during this 60-minute forum are: What challenges regarding benefits and risks in designing pediatric vaccine clinical trials, and in evaluating ongoing trials? What regulatory questions must IRBs consider when approving pediatric vaccine clinical trials? What are the ethical and regulatory considerations specific to clinical trials of SARS-CoV- 2 vaccines? Learning
February 12, 2021The proverbial saying ‘Necessity is the mother of invention’ is frequently used to explain how great innovations are made during times of urgent need. Never has the need been direr than when the COVID pandemic hit in March 2020 and health care providers were struggling to find treatments for patients fighting this new and deadly disease. It was during this time, ICTS investigator Eric Lenze, MD
-University Of North Carolina Chapel HillTraCS Regulatory invites academic researchers, scientists, study coordinators, and students engaged in clinical research/clinical trials to the Clinical Protocol Development Workshop. This two-day workshop will provide attendees with knowledge, tools, and resources to aid in the development of a scientific protocol for a clinical research study. There will be time for questions at the end of each
- January 12, 2021The CTSC Clinical Research Center (CCRC) at UC Davis Health received the Patient Safety Innovation Award for supporting the pioneering research into a #COVID-19 #pfizer #vaccine. Under the leadership of Daniel Nishijima, M.D., M.A.S., and Christopher Kain, RN, M.S.N., the team serves as the clinical component of the UC Davis Clinical and Translational Science Center (CTSC), funded by an NIH grant
University Of Southern CaliforniaWhether you are conducting a traditional clinical trial or a trial in the community, there are common strategies you should consider when recruiting participants for research. This toolkit introduces ideas on how to prepare early in the research process in order to increase the probability of meeting your participant recruitment goals. Subsequently, it will provide specific recommendations for
The Ohio State UniversityThis talk reviews methods and issues in precision medicine.
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University Of Southern California
The use of digital practices and approaches can potentially increase the quality and efficiency of all phases of the traditional clinical translational research process.This program helps research professionals and students who are involved in the health sciences to develop competency in digital research practices and approaches. The events and training resources introduce health researchers at
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University Of Southern California
Finding and enrolling participants in human studies has always been a challenge for the investigator and study personnel. Issues such as attrition, lack of participant engagement and clear communication, to name a few, can negatively impact recruitment and retention. This toolkit contains proven strategies and tips to help researchers develop a solid plan to recruit and retain study participants.
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University Of Southern California
In this 60-minute webinar, Dr. Tenaerts presents the work of the Clinical Trials Transformation Initiative (CTTI) and discusses two main topics regarding digital clinical trials: (1) moving ongoing trials to remote and (2) planning for decentralized trials.
December 11, 2020When his doctor told him that he had acute myeloid leukemia (AML) and less than a 1 in 5 chance of survival, David Zaas, M.D., thought first of his wife and how badly he wanted to see his two teenage children grow up. He wanted every opportunity to win his battle, and the opportunity to enroll in a phase 1 trial ensured that he was doing everything possible. Clinical trials are the only way to