clinical trials

The University of Pennsylvania will be conducting a mixed methods study, funded by NCATS through a bioethics supplement to the University of Pennsylvania’s CTSA, to examine institutional approaches to prioritizing COVID-19 trials. The goal of this study is to understand relevant processes and criteria applied during the pandemic, as well as perspectives on potentially extending these approaches to

The Society for Clinical Trials (SCT) issued a call for submissions for two awards: - Thomas C. Chalmers Student Scholarship (http://www.sctweb.org/chalmers.cfm): Students currently enrolled in a graduate degree program (Masters, PhD, or DrPH) at an accredited college or university, or postdoctoral fellows (who completed their PhD/DrPH within the last two years) are encouraged to apply. Three

For Argentino Calvo, a retired firefighter and paramedic from Bluffton, South Carolina, joining a COVID-19 vaccine trial was not just a personal choice but an investment in the health of his community. Calvo participated in the Novavax vaccine trial at MUSC, which was part of a large-scale study that recruited over 30,000 patients across 119 study sites in the United States and Mexico. SCTR co

Researchers from the University of Minnesota Medical School are collaborating with the Mayo Clinic to test the use of a senolytic therapy against COVID-19. The therapy targets the fundamental biology of aging. Initial findings, published June 8 in Science, suggest that using drugs to clear out older, damaged cells could reduce the inflammation and immune system overreaction that leads to severe or

The CTSA program was developed to accelerate new treatments from the lab to patients, enabled to a large extent by patients participating in and benefiting from clinical trials. Clinical trials provide that needed bridge from human subjects to hypotheses to treatments that can directly benefit human health. And, never has this connection been more critical than amid the global COVID-19 pandemic

No champion race car driver can win without a dedicated pit crew. The same is true in medical research. Thanks to their “pit crew” Mayo Clinic researchers were able to repurpose an experimental therapy, called lenzilumab, for patients with COVID-19 pneumonia, and from there into a phase three clinical trial — all in about one year. "I think we’ve accomplished in this year what normally would take

When Linda Thompson retired from the Virginia Department of Transportation in 2019, she started a new job the next day — getting fit. “My new job was going to American Family Fitness and getting in the pool and doing water aerobics,” said Thompson, 72. “I was really in bad shape when I retired. So it was time for me to take care of Linda.” Thompson lost 60 pounds over the next year. The exercise

Among the Southern California Clinical and Translational Science Institute's most important services to the research community are their support and tools (https://bit.ly/3qmjIb9) designed to help investigators overcome the all-too-familiar hurdle of clinical study recruitment. As a result, few people are more cognizant of the importance of participation in clinical research than the personnel of

Among the Southern California Clinical and Translational Science Institute's most important services to the research community are their support and tools (https://bit.ly/3qmjIb9) designed to help investigators overcome the all-too-familiar hurdle of clinical study recruitment. As a result, few people are more cognizant of the importance of participation in clinical research than the personnel of

Clinical trials help researchers discover and apply critical advances in patient care. Clinical trials follow rigorous scientific processes that usually take many years to complete. However, during the COVID-19 pandemic, people have been able to see and experience clinical trials operating on fast-forward. And a lot of people are wondering, "How do clinical trials work?" In this Q&A, the Mayo

Paul “Pee-J” Beverly doesn’t remember being airlifted to VCU Health from Lexington, Va., last fall. In fact, he doesn’t remember much of his COVID-19 experience at all. But his girlfriend, Angela Griffin, does. “It was one of the scariest things I’ve ever been through,” she said. “Not being able to see him, barely being able to talk to him. And knowing it was touch and go. They pretty much

Kate Marusina, director of the CTSC Clinical Trials Office, oversees a team that provides support for clinical trials at UC Davis. UC Davis conducts more than 2,000 research studies at any given time, including basic science, translational, and clinical trial research — all with the goal of bringing new, effective, and safe treatments to patients more quickly. In this brief interview conducted by

Social distancing and lockdowns may have reduced the spread of COVID-19, but researchers from Penn State College of Medicine also report those actions may have affected clinical researchers’ ability to finish trials. Study completion rates dropped worldwide between 13% and 23%, depending on the type of research sponsor and geographic location, between April and October 2020. Researchers previously

The proverbial saying ‘Necessity is the mother of invention’ is frequently used to explain how great innovations are made during times of urgent need. Never has the need been direr than when the COVID pandemic hit in March 2020 and health care providers were struggling to find treatments for patients fighting this new and deadly disease. It was during this time, ICTS investigator Eric Lenze, MD