- Main navigation
- CLIC & The CTSA Program
- News & Events
- Groups
- Common Metrics Initiative
- Education & Career Development
- Team Science & Collaboration
- Resources
- CTSA Program Projects & Initiatives
- Contact
- Search
A large randomized, placebo-controlled clinical trial led by the National Institutes of Health shows that treating adults hospitalized with COVID-19 with infliximab or abatacept — drugs widely used to treat certain autoimmune diseases — did not significantly shorten time to recovery but did substantially improve clinical status and reduce deaths. Some COVID-19 patients experience an immune
The Washington University Institute of Clinical and Translational Sciences (ICTS) hosted their 4th annual Symposium and Poster Display on Friday, May 13, 2022. The theme “Making an Impact, Shaping the Future” focused on strategies to address equity and diversity challenges experienced by institutions across the national Clinical and Translational Science Awards (CTSA) network. The hybrid event
When scientific advances burst into the news, such as a new medication to treat COVID-19 or a new concept like CRISPR for gene editing, people get a glimpse of how a scientific idea becomes a treatment or a tool. But what's the full story? Where did that idea come from? What happens in the research lab before clinical trials begin? How is scientific discovery transformed into a potential therapy
A new video sponsored by the University of Arkansas for Medical Sciences (UAMS) Translational Research Institute (TRI) is being used to help raise awareness among researchers about the inclusion of older adults in research. The five-minute video also has tips for helping researchers recruit more adults over age 65. The video was produced in collaboration with the UAMS Northwest Regional Campus
Objective: Agonism of protease-activated receptor (PAR) 1 by activated protein C (APC) provides neuro- and vasculoprotection in experimental neuroinjury models. The pleiotropic PAR1 agonist, 3K3A-APC, reduces neurological injury and promotes vascular integrity; 3K3A-APC proved safe in human volunteers.
Session recordings and slide presentations are now available from the 2021 REKS Summer Series Recording: Pathway to Decentralized Clinical Trials. The goal of this series is to discuss new developments in regulations affecting decentralized clinical trials. - Introduction to Decentralized Clinical Trials" featuring Nichelle Cobb (SMART IRB) - June 16th - Options for In-Home Clinical Trial Visits"
Yale School of Medicine (YSM) and its Yale Center for Clinical Investigation (YCCI) has had great success addressing the issue of minority participation in clinical trials. Two elements that are key to the successes at Yale are electronic health record strategies and community engagement, through the Cultural Ambassador program (partnership between Yale, the African Methodist Episcopal Zion Church
The Society for Clinical Trials (SCT) issued a call for submissions for two awards: - Thomas C. Chalmers Student Scholarship (http://www.sctweb.org/chalmers.cfm): Students currently enrolled in a graduate degree program (Masters, PhD, or DrPH) at an accredited college or university, or postdoctoral fellows (who completed their PhD/DrPH within the last two years) are encouraged to apply. Three
For Argentino Calvo, a retired firefighter and paramedic from Bluffton, South Carolina, joining a COVID-19 vaccine trial was not just a personal choice but an investment in the health of his community. Calvo participated in the Novavax vaccine trial at MUSC, which was part of a large-scale study that recruited over 30,000 patients across 119 study sites in the United States and Mexico. SCTR co
The CTSA program was developed to accelerate new treatments from the lab to patients, enabled to a large extent by patients participating in and benefiting from clinical trials. Clinical trials provide that needed bridge from human subjects to hypotheses to treatments that can directly benefit human health. And, never has this connection been more critical than amid the global COVID-19 pandemic
No champion race car driver can win without a dedicated pit crew. The same is true in medical research. Thanks to their “pit crew” Mayo Clinic researchers were able to repurpose an experimental therapy, called lenzilumab, for patients with COVID-19 pneumonia, and from there into a phase three clinical trial — all in about one year. "I think we’ve accomplished in this year what normally would take
Join the University at Buffalo Clinical and Translational Science Institute (CTSI) and the Medical University of South Carolina (MUSC) South Carolina Clinical and Translational Research (SCTR) from 10:00 a.m. to 5:00 p.m. EST on Tuesday, November 9, for a one-day virtual workshop on remote trials. The workshop will include a series of keynote presentations (and Q&A) in the morning followed by
Among the Southern California Clinical and Translational Science Institute's most important services to the research community are their support and tools (https://bit.ly/3qmjIb9) designed to help investigators overcome the all-too-familiar hurdle of clinical study recruitment. As a result, few people are more cognizant of the importance of participation in clinical research than the personnel of
Among the Southern California Clinical and Translational Science Institute's most important services to the research community are their support and tools (https://bit.ly/3qmjIb9) designed to help investigators overcome the all-too-familiar hurdle of clinical study recruitment. As a result, few people are more cognizant of the importance of participation in clinical research than the personnel of
On July 8 from 1 to 2 p.m., as The Miami Clinical and Translational Science Institute (CTSI) will host four Principal Investigators from the University of Miami for a virtual presentation to discuss the challenges and barriers as well as the strategies and best practices for recruiting underrepresented minorities into their various clinical research studies.
Clinical trials help researchers discover and apply critical advances in patient care. Clinical trials follow rigorous scientific processes that usually take many years to complete. However, during the COVID-19 pandemic, people have been able to see and experience clinical trials operating on fast-forward. And a lot of people are wondering, "How do clinical trials work?" In this Q&A, the Mayo
COVID-19 has thrown a wrench into research conduct, forcing hospitals and universities to transfer their research plans, data collection procedures, survey dissemination processes, and participant engagement methods quickly and nimbly to online venues. In addition, the state of research operations has changed dramatically due to the pandemic. This guide provides key considerations for ensuring
Clinical trials are a fundamental tool in evaluating the safety and efficacy of new drugs, medical devices, and health system interventions. Clinical trial visits generally involve eligibility assessment, enrollment, intervention administration, data collection, and follow-up, with many of these steps performed during face-to-face visits between participants and the investigative team.