University of Minnesota Twin Cities

  • The de Beaumont Foundation recently recognized Chao Yang of the Clinical and Translational Science Institute (CTSI) at the University of Minnesota as one of the “40 under 40 in Public Health.” Yang is the Assistant Director of CTSI's Community Engagement to Advance Research and Community Health (CEARCH) function. The award recognizes leaders in public health who are improving the health of

  • A growing body of research points to the profound effects of structural and interpersonal racism on health equity. This is particularly true when it comes to cardiovascular disease and related conditions, such as high blood pressure and obesity. In Minnesota, people of color experience some of the worst health disparities in the U.S. The Center for Chronic Disease Reduction and Equity Promotion

  • Oct. 28, 2021 - 7T MRI Knee Imaging - Translational Research Towards Clinical Applications - a virtual workshop organized by University of Minnesota Clinical and Translational Science Institute and the Center for Magnetic Resonance Research
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    University of Minnesota Twin Cities
    The virtual imaging workshop features an interactive format in which participants will experience real-time scanning of the knee at 7T and access to University of Minnesota imaging experts. The workshop will appeal to: Clinical investigators who currently use or anticipate using UHF imaging in their clinical practice MRI technologists who are interested in learning about knee imaging strategies at
  • Researchers from the University of Minnesota Medical School are collaborating with the Mayo Clinic to test the use of a senolytic therapy against COVID-19. The therapy targets the fundamental biology of aging. Initial findings, published June 8 in Science, suggest that using drugs to clear out older, damaged cells could reduce the inflammation and immune system overreaction that leads to severe or
  • With funding from CTSI, University of Minnesota researchers worked with local Indigenous community partners to develop evidence-based and culturally appropriate COVID-19 resources, creating three distinct fact sheets on staying healthy and staying connected during the pandemic. The project, “Helping Indigenous communities stay connected in light of COVID-19,” was conducted by the Memory Keepers

  • About the Job Memory Keepers Medical Discovery Team (MK-MDT) conducts research on dementia and its associated risks and co-morbidities in collaboration with Indigenous and rural communities in the Great Lakes Region. Our modern facilities have been thoughtfully constructed to foster team science approaches to research and well-being. The MK-MDT works collaboratively with Faculty Investigators from

  • Community engagement is the bridge that connects researchers and local communities; however, face-to-face engagement is often limited in reach and scale — especially during a pandemic. In a recently published paper, researchers from Mayo Clinic and the University of Minnesota evaluated the feasibility of a virtual statewide Facebook community platform to enhance public trust and engagement with

  • A banner for Research Ethics Day 2021 featuring the University of Minnesota logo, an image of a researcher holding a vial, and a graph with the words, "Coronavirus Vaccine Research"
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    University of Minnesota Twin Cities
    Hear from top national experts on how the COVID-19 pandemic is changing research ethics. Experts will discuss how to advance ethics and equity when conducting pandemic research, how to reconcile the need for research with the clinical imperative to save lives, and how the pandemic is affecting research design. As a large, public, land-grant research university, we aim to explore these vital issues
  • About the Job The CEARCH Assistant Director builds and nurtures relationships across different communities and the University; works collaboratively with the CEARCH Management Council, CEARCH leadership, and CTSI faculty and staff to develop, lead and sustain community-engaged research initiatives, programs and activities; and manages a portfolio of operations, projects and collaborations

  • Clinical and Translational Research Services (CTRS) is charged with providing high quality and efficient support for human subjects research, serving the entire clinical and translational research enterprise at the University of Minnesota. The CTRS Operations Director is part of the strategic leadership of CTRS, under the direction of the CTRS Director and Associate Director. The CTRS Operations

  • Urea Cycle Disorders Consortium

    Urea cycle disorders (UCDs) are rare but devastating genetic conditions. In 2003, the Urea Cycle Disorders Consortium (UCDC) became one of the first members of the RDCRN. Since then, UCDC has flourished into an international network of 16 academic centers in the United States, Canada and Europe that provide state-of-the-art care and conduct cutting-edge clinical research. The UCDC is currently

  • Nephrotic Syndrome Rare Disease Clinical Research Network III (NEPTUNE)

    Focal and Segmental Glomerulosclerosis, Minimal Change Disease, and Membranous Nephropathy, presenting as Nephrotic Syndrome (NS), are a group of rare renal diseases that may cause serious complications and end-stage kidney disease, generating significant individual, societal and economic burdens. The Nephrotic Syndrome Study Network (NEPTUNE) brings together physician scientists at 26 sites in

  • Lysosomal Disease Network (LDN)

    Lysosomal disorders (LD) are a group of approximately 70 inherited conditions resulting from defects in lysosomal function, usually the deficiency of a single enzyme required for the metabolism of lipids, glycoproteins, or mucopolysaccharides. Collectively, LD are not especially rare, and estimates suggest that roughly 1 in 5,000 newborns will be affected with one identified LD. However, each

  • Frontiers in Congenital Disorders of Glycosylation (FCDGC)

    Congenital disorders of glycosylation (CDG) consist of more than 130 different inborn errors of metabolism at an estimated overall incidence of greater than 1 in 100,000. While these disorders were first genetically defined in the 1990s, there is no data available on their natural history, no comprehensive patient registry, no reliable screening tests for many types, and large gaps in clinical

  • Congenital and Perinatal Infections Rare Diseases Clinical Research Consortium (CPIC)

    The Congenital and Perinatal Infections Consortium (CPIC) is focused on reducing the morbidity and mortality of rare viral infections such as congenital cytomegalovirus (CMV) disease, neonatal herpes simplex virus (HSV) infection, and neonatal viral sepsis caused by enteroviruses (EVs) and the related human parechoviruses (HPeVs). These infections have been grouped together because of their

  • University of Minnesota Twin Cities

    This poster describes the Mothers Leading Science (MLS) program developed by the University of Minnesota - CTSI and the evaluation of the first cohort, especially as the program has supported the participants during the pandemic. MLS is a year-long leadership development program for research-intensive female faculty in the health sciences who are raising school-age and/or young children. The

  • An award-winning smartphone app spearheaded by the University of Minnesota integrates a patient’s responses with the healthcare provider’s electronic health records (EHR) system.

  • Electronic health records are painting a detailed picture of COVID-19 testing, infections, and hospitalizations. This statewide effort—which includes CTSI and several healthcare providers—could help identify disparities and inform interventions to improve outcomes for all Minnesotans.

  • Accelerating research has become more important than ever in the face of a global pandemic. By creating a model that meets the need for speed, the University of Minnesota can hasten the development of therapeutics—not just for one candidate, but for COVID-19 treatments being developed across UMN.

  • Shortly after healthcare system M Health Fairview converted Bethesda into a COVID-19 hospital, they teamed up with the University of Minnesota CTSA. Together, the partners built a robust infrastructure for COVID-19 research, pursuing innovative ways to engage Bethesda patients in the research process and optimize the way studies are conducted.

  • To mitigate risk of COVID-19, two University of Minnesota (UMN) researchers are analyzing factors such as race, economic stability, living environment, education, and more to get a more comprehensive, holistic picture of health.
  • SIREN Logo

    The Strategies to Innovate EmeRgENcy Care Clinical Trials Network (SIREN) is a clinical trials network funded by the National Institute for Neurological Disorders and Stroke (NINDS), the National Heart Lung and Blood Institute (NHLBI) and the National Center for Advancing Translational Science (NCATS). The goal of the SIREN Network is to improve the outcomes of patients with neurologic, cardiac

  • Association for Clinical and Translational Science
    University of Minnesota Twin Cities
    Other
    The Biostats4you website was developed to serve medical and public health researchers and professionals who wish to learn more about biostatistics. The site contains carefully selected and vetted training materials especially suited for a non-statistician audience. This site is being developed and maintained by members of the Biostatistics, Epidemiology and Research Design Special Interest Group
  • A University of Minnesota researcher is co-leading an effort to test wastewater across Minnesota. This would help scientists and public health officials see how prevalent COVID-19 is in a given community and understand where the virus is spiking or trending downward.
  • CTSA members are helping drive new research and clinical opportunities in ultra-high field magnetic resonance imaging (UHF MRI), evidenced by a November conference on the topic for the national CTSA community hosted by the University of Minnesota.
  • Drawing of a network on a global

    With an emphasis on educational issues and a goal of sharing resources, best practices and facilitating collaboration, members of the Midwest Consortium (MC) partner to strengthen clinical research education programs, mentoring, and career development opportunities for scholars. The Midwest Consortium for education and research collaboration began in 2006 with three Roadmap K12 institutions

  • The Biorepository and Laboratory Services (BLS) Program Director leads an integrated biospecimen core program within the University of Minnesota’s Clinical and Translational Science Institute (CTSI). This encompasses oversight and expansion of BioNet, the University’s Biological Materials Procurement Network, as well as further development and oversight of new activities of the Biorepository and
  • The conference aims to identify the promise of ultra-high field MRI at addressing unmet clinical needs, highlight the current and future technologies required to fully exploit 7T in addressing these applications, and discuss the cost-benefit question, “Does the availability of 7T improve clinical outcomes?”.
  • The University of Minnesota CTSI is hosting a conference in collaboration with the University of Minnesota Center for Magnetic Resonance Research entitled, “Toward the Clinical Translational of Ultra-High Field MRI”.
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    University of Minnesota Twin Cities
    The University of Minnesota CTSI, in collaboration with the University of Minnesota Center for Magnetic Resonance Research, is hosting a conference, “Toward the Clinical Translation of Ultra-High Field MRI”, for the national CTSA community on November 18-19, 2019 in Minneapolis, MN. The continued development and availability of ultra-high field MRI systems along with recent FDA approval of 7T MRI
  • Pediatric Medical Device Innovation
    University of Minnesota Twin Cities

    Pediatric medical technology advancement is about a decade behind adult technology advancement. This technology lag was reflected in a lack of pediatric-specific innovation within the University of Minnesota (UMN). To address this institutional and national deficit, we developed a novel program around pediatric technology innovation. The Pediatric Health Innovation Program (PHIP) at the UMN