University of Virginia

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    integrated Translational Health Research Institute of Virginia

    The integrated Translational Health Research Institute of Virginia (iTHRIV) program is a collaboration of public and private institutions across the Commonwealth of Virginia that brings team science, innovation, and a commitment to train the next generation of clinical and translational researchers. Together, the iTHRIV partners (University of Virginia (Central VA), Virginia Tech and Carilion Clinics (Southwestern VA) and Inova Health Systems (Northern VA)) and our affiliates (Center for Open Science and the Licensing and Ventures Group) are working to support clinical translational research to benefit our diverse rural and urban communities across the state. The mission of iTHRIV is to remove barriers to discovery and optimize the use of data to improve health.
  • Save the date for the 2021 iTHRIV Scholars Symposium
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    University of Virginia

    Join us as we celebrate our iTHRIV scholars at the 4th Annual iTHRIV Scholars Clinical Translational Research Symposium on October 19 at 1 PM. Each year, the symposium includes a keynote address from Elizabeth O. Ofili, MD, MPH, FACC, an information session for prospective scholars, and research lightning talks from our current cohort and recent graduates. This year’s event will be virtual and

  • The Integrated Translational Health Research Institute of Virginia (iTHRIV) with support from the University of Pittsburgh (UPitt) is participating in the “Building Up a Diverse Workforce for Biomedical Research” study. Building Up is a national study led by the University of Pittsburgh (UPitt) and aims to test the effectiveness of a career development intervention developed for postdocs and

  • The Foundations of Biomedical Data Science at the University of Virginia hosted its fifth annual Biomedical Data Science Innovation Lab (BDSIL): Challenges in Brain Analytics and Data Integration on June 21-25, 2021. The BDSIL is an intensive program partially sponsored by iTHRIV and NIH Grant #R25GM139080 that has virtual and in-person components designed to foster the development of

  • Sample code templates developed by the iTHRIV CTSA team enable rapid analytics onboarding to the National COVID Cohort Collaborative (N3C) Data Enclave. The National COVID Cohort Collaborative (N3C) Data Enclave is an analytics platform containing clinical data from electronic health records from over 55 sites around the country. This data from SARS-CoV-2 positive patients (and matched controls)

  • UVA-iTHRIV Brain Institute
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    University of Virginia

    Applications are still open! We will be accepting applicants on a rolling basis with final applications due by 11:59PM ET, January 31, 2022 The University of Virginia is organizing a Biomedical Data Science Innovation Lab to foster the development of new interdisciplinary teams via a facilitated and mentored format to tackle data science challenges arising from the use of large-scale neuroscience

  • UVA-iTHRIV Brain Institute
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    University of Virginia

    iTHRIV is pleased to be a sponsor of the 2021-2022 Biomedical Data Science Innovation Lab (BDSIL). This year's topic is Ethical Challenges of Artificial Intelligence (AI) in Biomedicine. This BDSIL will promote collaboration between quantitative and biomedical researchers towards the development of novel or significantly adapted models, methods, and approaches for overcoming difficult ethical

  • The iTHRIV Research Data Commons is a new solution that provides health researchers and data stewards with a single interface to manage, share and use research data throughout its lifecycle, from initial design and approval through data collection and analysis, and ultimately publication. The product facilitates access while enhancing compliance, making it a win for both research teams and

  • The brain accounts for only about 2% of our body’s weight, however it utilizes up to 20% of the body’s energy which is mostly delivered through the blood circulation of oxygen and nutrients. The brain, therefore needs a constant and consistent supply of blood and well-functioning blood vessels. Neurological pathologies, such as Alzheimer’s disease have a connection with impaired blood vessel

  • When you’re solving a challenging math problem, you know your brain is working hard. But what, exactly, is going on in there? Despite decades of research into math teaching and learning, there is still much to learn about how specific brain functions are tied to math skills.

  • iTHRIV full partnership logo
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    University of Virginia

    Jonathan Brammer, MD will present "Targeting Interleukin-15 (IL-15) in T-cell Large Granular Lymphocytic Leukemia" for his CTSA Visiting Scholar Lecture.

  • UVA-iTHRIV Brain Institute
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    University of Virginia

    The dendritic (input) and axonal (output) arbors of neurons are extremely diverse, affecting both signal processing and activity propagation throughout the network. We will present a framework conceptually and quantitatively linking neuron morphology and circuit connectivity using the hippocampal formation as a practical example. This approach provides a comprehensive yet compact neuronal

  • UVA-iTHRIV Brain Institute
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    University of Virginia

    Neuroimaging meta-analysis offers the opportunity to examine consensus and reproducibility across published studies and translate this knowledge into improved neurocognitive models. Here, I will review the development of neuroimaging meta-analysis methods and provide a review of applications from across multiple cognitive and clinical domains. Advanced meta-analytic approaches will be described

  • UVA-iTHRIV Brain Institute
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    University of Virginia

    Transcriptional regulation plays a critical role in many biological processes including cell development and cancer formation. Identification of active enhancers and transcription factors responsible for regulating gene expression is an essential problem in functional genomics. With novel integrative modeling approaches, massive publicly available multi-omics data can be a useful resource for gene

  • UVA-iTHRIV Brain Institute
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    University of Virginia

    The focus of neuroimaging studies has slowly shifted from mapping specialized systems common to healthy individuals, to understanding how individual variability in these systems allows for the rich phenotypic differences in our population. As individual difference approaches have become more common, concern about reliability of findings has emerged in the field. In order to appropriately leverage

  • UVA-iTHRIV Brain Institute
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    University of Virginia

    Given the intrinsically large and complex data sets collected in neuroimaging research, coupled with the extensive array of shared data and tools amassed in the research community, ReproNim seeks to lower the barriers for efficient: use of data; description of data and process; use of standards and best practices; sharing; and subsequent reuse of the collective ‘big’ data. Aggregation of data and

  • UVA-iTHRIV Brain Institute
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    University of Virginia

    This talk will present the pillars and rationale of Open Big Neuroscience, present the important characteristics of Big Biomedical Data and challenges with sharing sensitive information. The DataSifter technique for novel statistical obfuscation of sensitive will be demonstrated. Some case-studies illustrating applications to Neurodegenerative Disease, Autism Brain Imaging Data Exchange, and

  • UVA-iTHRIV Brain Institute
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    University of Virginia

    The Foundations of Biomedical Data Science virtual seminar series is an exciting and topical set of regularly scheduled, weekly, webinar presentations covering the basics of data management, representation, computation, statistical inference, data modeling, & other topics relevant to “big data” biomedicine. The seminar series provides fundamental topic introductions suitable for individuals at all

  • UVA-iTHRIV Brain Institute
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    University of Virginia

    Dr. Petzinger's work focuses on understanding how to promote brain repair after injury, particularly in the context of Parkinson's disease. The focus of this talk will be to review mechanisms of exercise induced neuroplasticity in a rodent model of Parkinson's disease and to examine exercise effects on cognition and motor performance in Parkinson's disease. Speaker Bio: Dr. Giselle Petzinger is an

  • UVA-iTHRIV Brain Institute
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    University of Virginia

    You are invited to join us on January 8th, 2021, 9am Pacific/12pm Eastern, for the first online presentation of 2021 in the Foundations of Biomedical Data Science Seminar Series! Our featured speakers will be Dr. Karen Johnston and Johanna Loomba from University of Virginia discussing "Introduction to Use of Structured Medical Record Data." Abstract: Electronic medical record (EMR) data is encoded

  • Clinical Research in ALS and Related Disorders for Therapeutic Development (CReATe)

    Amyotrophic lateral sclerosis (ALS) is a fatal disease that involves progressive death of motor nerves in the brain, brainstem, and spinal cord. The disease is closely related to disorders such as primary lateral sclerosis, hereditary spastic paraplegia, progressive muscular atrophy, and frontotemporal dementia. These diseases have shared genetic causes and underlying biology as well as a shared

  • University of Virginia

    The Foundations of Biomedical Data Science virtual seminar series is an exciting and topical set of regularly scheduled, weekly, webinar presentations covering the basics of data management, representation, computation, statistical inference, data modeling, & other topics relevant to “big data” biomedicine. The seminar series provides fundamental topic introductions suitable for individuals at all

  • University of Virginia
    Virginia Tech
    Carilion Clinic

    The iTHRIV Scholars Program is a two-year, cohort-based, mentored, career development award open to eligible junior faculty candidates at the University of Virginia (UVA) and Virginia Tech Carilion (VTC). Awardees participate in weekly curriculum sessions focused around developing their careers in clinical and translational research, including sessions focused on data science, team science, peer

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    University of Virginia
    3rd Annual iTHRIV Scholars Symposium - Sept. 29th 1-3:30 PM EST Join us for an afternoon of panel discussions, Q&A's, and a keynote address Using Genomic and Environmental Methods to Unravel Hypertension Health Disparities in Black Women from Jacqueline Taylor, PhD The digital poster room is live in Mozilla Hubs Click Here to View the Posters
  • UVA Innovation Lab
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    University of Virginia

    Challenges in Brain Analytics and Integration A hybrid event with four virtual microlabs and a five-day residential workshop focused on neuroscientific analytics and integration for quantitative and biomedical researchers. Five virtual sessions: October 2, 2020, April 16, 2021, May 21, 2021, June 11, 2021, 12-2pm ET A five-day residential workshop for neuroscientific quantitative and biomedical