University Of North Carolina Chapel Hill

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    North Carolina Translational and Clinical Sciences Institute (NC TraCS)

    Our mission is to develop and support a skilled research workforce, engage diverse stakeholders as active partners, develop innovative methods to address barriers to translating scientific findings, and incorporate cutting-edge informatics tools and methodologies in every aspect of translational research.

    We educate, fund, connect, and support research teams.

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    University Of North Carolina Chapel Hill

    The Catalyze Program, established by NHLBI and run by Research Triangle Institute (RTI) International, transforms basic science discoveries into viable therapeutics, devices, and diagnostics. While the actual Catalyze Program is focused on products for heart, lung, blood, and sleep disorders, the information presented in these monthly seminars is foundational knowledge about product development

  • The University of North Carolina at Chapel Hill (UNC) seeks a high-energy, service-oriented leader for the position of Director of the Office of Human Research Ethics (OHRE http://research.unc.edu/offices/human-research-ethics/). The OHRE is responsible for ethical and regulatory oversight of all research at UNC that involves human subjects. The OHRE oversees the planning, direction, and execution

  • John Baratta, MD, MBA helped start the UNC COVID Recovery Clinic—where patients can get help for their ongoing symptoms and doctors can gather valuable data. “We don’t have a lot of specific, scientific answers because it’s just all so new,” Baratta says. “Through research, that’s what we and others have to figure out.” To start finding answers for patients with "long COVID," the clinic team, with

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    University Of North Carolina Chapel Hill

    Hereditary hemorrhagic telangiectasia (HHT) is a hereditary multisystem vascular disease of abnormal angiogenesis and the second most common hereditary bleeding disorder in the world. Harvard KL2 Scholar Hanny Al-Samkari, MD will describe the revolutionary potential of anti-angiogenic therapy in HHT and the evidence to date for systemic bevacizumab as a treatment for bleeding and anemia in HHT.

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    University Of North Carolina Chapel Hill

    The opioid crisis response has largely overlooked multiple patient populations with complex opioid-related vulnerabilities, including older adults with cancer or dementia. Join Andrew Roberts, a CTSA KL2 Scholar who trained at UNC, for a presentation of findings from his work examining high-risk opioid use patterns and outcomes in older adult cancer survivors. He will also discuss future

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    University Of North Carolina Chapel Hill

    The Data Manager is responsible for the complete data process: from design, to build, to quality control, to cleaning, and finally to archiving. In smaller research teams, this role may be absent or overlooked due to other pressing tasks, or may be parceled out as extra duties among team members. TraCS is hosting this training to help research teams develop better data managers. We will review

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    University Of North Carolina Chapel Hill

    Adopting a Population Health Strategy to Aggressively Reduce Cardiovascular Risk: It Works in Rural Communities Too! Sam Cykert, MD will describe how implementation of the Heart Health Now study affected cardiovascular risk when applied to high-risk patients in 219 practices across North Carolina. Half of these practices were in rural areas and a quarter of high-risk patients were Black. The

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    University Of North Carolina Chapel Hill

    Malawi has the highest cervical cancer burden in the world—at least partly attributable to the low use of screening services. Join Corrina Moucheraud, a CTSA KL2 Scholar, to discuss her work that includes qualitative interviews with Malawian women and men and clinical and implementation data from “screen and treat” programs. She will highlight new findings about the complex and multi-level factors

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    University Of North Carolina Chapel Hill

    This interactive online workshop will provide an introduction to focus groups, a data collection method used in qualitative research. Topics covered will include focus group methodology, considerations for planning a focus group, development of focus group discussion guides, focus group facilitation skills, and tips for conducting virtual focus groups. Attendees will also participate in a mini

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    University Of North Carolina Chapel Hill

    This interactive online workshop will focus on semi-structured interviewing, a data collection method used in qualitative research. Topics covered will include basics of semi-structured interviews, development of interview questions and probes, interviewing skills, and considerations for conducting virtual interviews. Participants will have the opportunity to practice developing interview

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    University Of North Carolina Chapel Hill

    Join the NRP for their latest education session. Andrew Thorne, PharmD, MS and Justin Davis from the Investigational Drug Services (IDS) Pharmacy will be presenting on their new billing models. Presentation Topics Includes: Explain details of IDS billing model Define terms used in IDS billing model Respond to questions from research community regarding IDS billing Attendance at this event is

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    University Of North Carolina Chapel Hill

    TraCS Regulatory invites academic researchers, scientists, study coordinators, and students engaged in clinical research/clinical trials to the Clinical Protocol Development Workshop. This two-day workshop will provide attendees with knowledge, tools, and resources to aid in the development of a scientific protocol for a clinical research study. There will be time for questions at the end of each

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    University Of North Carolina Chapel Hill

    Andrea Knittel's research focuses on the effects of the criminal legal system on women's reproductive transitions. This virtual presentation will highlight the methods and strategies used in recruiting women who have experienced incarceration and the people from their personal social networks. The Inclusive Science Program (ISP) at the North Carolina Translational and Clinical Sciences (NC TraCS)

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    University Of North Carolina Chapel Hill

    Join us as Pearman Parker, PhD from the University of Arkansas for Medical Sciences presents the results from her KL2 project where she investigated the perceptions of cancer educational materials among young women breast cancer survivors. She will also discuss the results from an environmental scan of cancer educational materials for content and readability and present her next steps toward grant

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    University Of North Carolina Chapel Hill

    Learn how to leverage the National Heart, Lung, and Blood Institute’s (NHLBI) new translational grant funding programs to accelerate the development of your preclinical heart, lung, blood or sleep technology. The NHLBI recently launched the Catalyze program to empower and support translational research through a comprehensive suite of funding, technical services, training, and mentorship to

  • Working towards a cure for HIV requires many things, including tenacity, determination, and collaboration. Nilu Goonetilleke, PhD – an immunologist in the University of North Carolina School of Medicine – is well-equipped to meet this challenge. Learn more about how Goonetilleke is changing the trajectory of HIV with research support from the North Carolina Translational and Clinical Sciences (NC

  • Nephrotic Syndrome Rare Disease Clinical Research Network III (NEPTUNE)

    Focal and Segmental Glomerulosclerosis, Minimal Change Disease, and Membranous Nephropathy, presenting as Nephrotic Syndrome (NS), are a group of rare renal diseases that may cause serious complications and end-stage kidney disease, generating significant individual, societal and economic burdens. The Nephrotic Syndrome Study Network (NEPTUNE) brings together physician scientists at 26 sites in

  • Myasthenia Gravis Rare Disease Network (MGNet)

    Myasthenia gravis (MG) is an autoimmune disease that blocks the signal from nerve to muscle, producing weakness. The nature of the disease can range from isolated severe vision problems, like drooping eyelids or double vision, to profound general weakness leading to breathing muscle failure. Although the cause of MG is not known, the disease appears to vary based on several factors, including the

  • Genetic Disorders of Mucociliary Clearance Consortium (GDMCC)

    The Genetic Disorders of Mucociliary Clearance Consortium (GDMCC) focuses on several inherited and acquired disorders that cause thickened, infected secretions to accumulate in the upper and lower airways. Its work is conducted at eight clinical research sites across the United States and Canada. During the past 15 years, the consortium has made numerous advances that profoundly changed clinical

  • Brain Vascular Malformation Consortium (BVMC)

    The Brain Vascular Malformation Consortium (BVMC) focuses on three rare brain conditions: familial cerebral cavernous malformation (CCM), Sturge-Weber syndrome (SWS), and hereditary hemorrhagic telangiectasia (HHT). These disorders are poorly understood, costly to manage, and can cause serious complications such as hemorrhages, seizures, and problems with spinal cord, nerve or brain function. Over

  • The Community and Stakeholder Engagement Program at the North Carolina Translational and Clinical Sciences (NC TraCS) Institute works to promote and facilitate the development of long-lasting and meaningful research partnerships between clinical and translational researchers and diverse stakeholders from across North Carolina. When implemented with planning and open-mindedness, community and

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    University Of North Carolina Chapel Hill

    This interactive, online workshop will focus on semi-structured interviewing, a data collection method used in qualitative research. Topics covered will include basics of semi-structured interviews, development of interview questions and probes, interviewing skills, considerations for conducting virtual interviews, and trauma-informed interviewing. Participants will have the opportunity to

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    University Of North Carolina Chapel Hill

    Myron Cohen, MD will discuss the progress we have made during the COVID-19 pandemic, and the work we still have left to do. Presentation topics include: -Provide latest updates and strategies to protect yourself and your communities -Describe investigational treatments and trials -Current impact of COVID-19 on the research agenda

  • Working towards a cure for HIV requires many things – tenacity, determination, and collaboration. In the early 1980s, when a patient received a diagnosis of HIV (human immunodeficiency virus), the individual was often told to get their affairs in order. Their life expectancy could range from just a few weeks to a few months. Today, a person may receive the same diagnosis and live for several more

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    University Of North Carolina Chapel Hill

    Developed by RTI International and funded by the North Carolina Translational and Clinical Sciences (NC TraCS) Institute's Inclusive Science Program, Semblie is an online platform that allows users to build, deliver, and track web-based interventions without the need for a developer or graphic artist. Following up on an earlier 3-part series that provided a general overview of Semblie, this

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    Oregon Health and Science University

    Many clinical questions have arisen with the COVID-19 pandemic, from who is at greatest risk for COVID-19 infection to adverse outcomes if infected to how COVID-19 has impacted healthcare utilization patterns. To help answer these questions, and many more, the National COVID Cohort Collaborative (N3C) has integrated real-world clinical observations from across the nation into a harmonized database

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    University Of North Carolina Chapel Hill

    Including non-English speaking participants in research requires us to translate our instruments. How we translate these tools can influence our results. Join the Multilingual Research Advancement for Health (MURAL) program and Michaela DuBay, PhD, CCC-SLP, for the second edition of the Fall 2020 MURAL Multilingual Research Capacity Building Lecture Series. We will discuss a cultural adaptation

  • Image of the COVID-19 coronavirus by Martin Sanchez on Unsplash
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    University Of North Carolina Chapel Hill

    In this first of a new monthly COVID-19 Journal Club, the North Carolina Translational and Clinical Science (NC TraCS) Institute Comparative Effectiveness Research (CER) team will lead a discussion of one of the now retracted articles using the Surgisphere data. What were the signs that led some to question the data source, and what should we look for in terms of study design in non-randomized

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    University Of North Carolina Chapel Hill

    The COVID-19 pandemic has completely upended our lives, disrupting the way we live, work, and interact with each other, and killing more than 210,000 Americans to date. Because any hope of a return to “normal” depends on antivirals, therapeutics, and vaccines against SARS-CoV-2, the virus that causes COVID-19, the importance of scientific research has never been more clear. Even before the