Study Design

A module on the research implications of aging, multimorbidity, polypharmacy, and inter-current health events.

This module describes the unique benefits of including older adults in clinical research.

Best practices for including older adults with cognitive impairments in clinical research.

This session will focus on multiple chronic conditions as a dimension of intersectionality needed for inclusion of older adults in research.

This annotated slide set introduces study teams to the NIH Inclusion Across the Lifespan Policy, and describes barriers and solutions to inclusion of older adults in research.

The content in this course was presented on April 18, 2018 in Washington, D.C., as part of the Association for Clinical and Translational Science (ACTS) 2018 meeting.

The D.K. Kim International Center for Regulatory Science, in conjunction with the Southern California Clinical and Translational Science Institute and the Greater Los Angeles Clinical and Translational Sciences Awards Consortium, hosts boot camps on current regulatory science topics regarding clinical trials. Boot camps are designed to address the needs of the clinical research team members, but

What information is most needed by patients and providers to make informed health care decisions? Learn from experts in risk evaluation and evidence synthesis about Methods for Prioritizing Research in Comparative Effectiveness Research.

Advantages and disadvantages of longitudinal studies, types of analyses used in longitudinal studies, sources of potential bias. Advantages and disadvantages of cross-sectional studies, types of analyses used in cross-sectional studies, sources of potential bias in cross-sectional studies, same elements for ecological studies To watch the full training, please go here: https://www.youtube.com

This course outlines basic concepts and terminology in the design of clinical/translational research projects targeting specific populations, and discusses methods to identify useful study populations within large and diverse cities.

The first section of this video lecture series discusses the process of developing a conceptual and statistical model that can most effectively test a hypothesis. The second section describes the role of systematic reviews of research literature and the statistical meta-analyses designed to collectively assess their findings.

In the first section, lectures cover potential sources of bias that can occur at all stages of research, and how to mitigate their impact on findings. The second section focuses on analysis of data in biomedical research, its presentation, statistical testing and conclusions.

This course introduces the mission and processes of Clinical and Translational Research (CTR). It demonstrates approaches to formulating and writing research questions and hypotheses appropriate to CTR.

The IMPACT (Instruction in Monitoring, Procedure Documentation and ClinicalTrials.gov) workshop series provides intermediate instruction for faculty, clinical research professionals with two or more years of experience and other study team members. Before attending this session, participants should have either used ClinicalTrials.gov or previously attended ClinicalTrials.gov registration training

Fundamentals of Clinical and Translational Science (FunCaTS) is a combination of 13 online modules strategically packaged together to enable medical professionals and allied health staff to expand their knowledge of the components of clinical and translational research. These components provide the fundamental knowledge to promote understanding of the process of bringing discoveries to the bedside

Are you ready to take a deeper dive into the world of clinical and translational science? Essentials of Clinical and Translational Science (ECaTS) provides medical professionals with foundational knowledge of research terminology, research methods and processes, clinical epidemiology, and biomedical statistics. Upon completion, learners understand basic terminology and methodological concepts in

More and more, grant proposals are requesting researchers to ensure that they have worked with or plan to integrate the community into their research proposal. One approach to this is to develop a community advisory board (CAB) who can provide feedback into all aspects of your research study including: 1) developing research questions; 2) developing recruitment plans; 3) reviewing study

Video lecture on conducting research with biorepositories

In this video, an SC CTSI specialist introduces the basic characteristics of community-engaged research and the rationale for this research approach, including the development of health solutions among groups that have historically been underrepresented in medical study. Clinical and translational investigators learn the ways in which community-engaged research differs from traditional research

Robert Strouse discusses how failure in research is not negative, lessons learned from research failure helps us learn and move forward

In this seminar, you will learn how to perform a sample size calculation. This seminar will explain the parameters required for sample size analyses and review methods and tools for sample size calculations.

Advantages and disadvantages of experimental studies, individual vs. group trials, preventive vs. therapeutic trials, parallel RCTs, factorial study design, new drug trials, sources of potential bias. Watch the full video here: https://youtu.be/fdgpFTo3bU0