University Of Alabama At Birmingham

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    Center for Clinical and Translational Science

    The CCTS vision is to reduce the burden of disease and disparities in health outcomes that disproportionately affect the underserved minority and special (i.e., socioeconomically disadvantaged, rural) populations within our region. This vision forms a common purpose among the institutions in our CCTS Partner Network. Working together, we will enhance the translation of fundamental and clinical research into improvements for human health and health care delivery. By further developing a diverse, well-trained workforce in translational science, by promoting an efficient scientific infrastructure, by engaging our communities in partnership to identify challenges and create approaches to solutions, and by assuring effective use of available resources, the CCTS Partner Network will accelerate the pace of discovery to delivery across the translational spectrum.
  • AI Against Cancer Data Science Hackathon
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    University Of Alabama At Birmingham

    The 2021 Data Science Hackathon will be held virtually online during August 9-10, 2021. This would be the third data science hackathon organized by the UAB Informatics Institute. We invite informaticians, statisticians, bioengineers, data scientists, cancer researchers, and oncologists at all levels to participate in solving cancer-related research, prevention, and healthcare practice problems

  • Annual Translational and Transformative Informatics Symposium
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    University Of Alabama At Birmingham

    The UAB Informatics Institute and Center for Clinical and Translational Science invites you to attend the 5th Annual Translational and Transformative Informatics Symposium (ATTIS)! This year’s symposium will be held Friday, April 23 virtually on Zoom. ATTIS 2021 offers faculty, postdoc trainees, and graduate students an opportunity to report progress on the latest informatics research and

  • CCTS Bioethics Forum
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    University Of Alabama At Birmingham

    The CCTS Bioethics Forum brings together researchers, bioethicists, students, community members, front-line research staff, and clinical staff to discuss ethical issues in research. This year's event will focus on the topic of "Equity and Trust for COVID-19 Testing, Treatment, and Vaccination: Where Do We Go from Here?"

  • CCTS TIERS (Training Interdisciplinary & Emerging Research Scholars)
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    University Of Alabama At Birmingham

    Presented by Michael Wiederman, PhD Director of Leadership and Professional Development and Professor, Family & Community Medicine The University of Alabama at Birmingham The pandemic presents unusual challenges for those in academia who are used to in-person meetings, teamwork, and working on campus. Join us for an interactive session focused on models and tools from psychology that have the

  • 8th Annual Rare Disease Genomics Symposium
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    University Of Alabama At Birmingham

    The University of Alabama at Birmingham, Children’s of Alabama, Alabama Rare and the Alabama Genomic Initiative will host the 8th Annual Rare Disease Genomics Symposium via Zoom on Friday, Feb. 26. and Saturday, Feb. 27. This two-day symposium will focus on science and research as well as patient advocacy. The sessions on Friday are focused for medical providers and researchers and the sessions on

  • Porphyrias Consortium (PC)

    The porphyrias are a group of rare, inherited disorders, each caused by a deficiency with one of eight enzymes necessary to produce heme, an important component of hemoglobin and other proteins. The porphyrias are classified as either acute hepatic (liver) or cutaneous (skin); the former is characterized generally by acute attacks of severe abdominal pain accompanied by nausea, vomiting and other

  • Frontiers in Congenital Disorders of Glycosylation (FCDGC)

    Congenital disorders of glycosylation (CDG) consist of more than 130 different inborn errors of metabolism at an estimated overall incidence of greater than 1 in 100 000. While they were first genetically defined in the 1990s, there is no data available on natural history, no comprehensive patient registry, no reliable screening tests for many types, and large gaps in clinical trial readiness. In

  • Congenital and Perinatal Infections Rare Diseases Clinical Research Consortium (CPIC)

    The Congenital and Perinatal Infections Consortium is focused on reducing the morbidity and mortality of rare viral infections such as congenital cytomegalovirus (CMV) disease, neonatal herpes simplex virus (HSV) infection, and neonatal viral sepsis caused by enteroviruses (EVs) and the related human parechoviruses (HPeVs). These infections have been grouped together because of their pathogenic

  • The Center for Clinical & Translational Science will use new grant to help grow the reach of I-Corps@NCATS in order to help scientists translate their discoveries to the marketplace.

  • Virginia Commonwealth University
    University of Nebraska Medical Center
    University Of Washington
    University Of Alabama At Birmingham
    University Of North Carolina Chapel Hill
    Johns Hopkins University
    Mayo Clinic
    Oregon Health and Science University

    Many clinical questions have arisen with the COVID-19 pandemic, from who is at greatest risk for COVID-19 infection to adverse outcomes if infected to how COVID-19 has impacted healthcare utilization patterns. To help answer these questions, and many more, the National COVID Cohort Collaborative (N3C) has integrated real-world clinical observations from across the nation into a harmonized database

  • University Of Alabama At Birmingham
    The vision of the Center for Clinical and Translational Science (CCTS) based at the University of Alabama at Birmingham is to reduce health disparities in diseases disproportionately represented within the Deep South as we accelerate discovery to improve human health. Through our Partner Network – spanning Alabama, Mississippi and Louisiana – the CCTS ensures that our research and training efforts
  • University Of Massachusetts Med Sch Worcester
    University Of Alabama At Birmingham
    Vanderbilt University Medical Center

    INTRODUCTION Under-representation in health-related research is one of a multitude of factors that contribute to health disparities experienced by African American and Latinx communities, and has been brought to the forefront in the context of the COVID-19 pandemic. Barriers to research participation stem from historical social injustices, are multi-faceted and include factors specific to the

  • Community Engagement Institute 2020
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    University Of Alabama At Birmingham

    The Community Engagement Institute (CEI) will host a half-day virtual symposium on Friday, October 2, 2020 from 9:00 am – 1:00 pm that will focus on health equity and social justice. CEI is a regional program that brings community members, leaders, researchers, and philanthropic stakeholders together to share perspectives, to build relationships and to explore common goals. This year’s event,

  • DSC_RDCRN
    The Developmental Synaptopathies Consortium is composed of a group of medical centers throughout the US studying three related rare genetic syndromes that often cause autism spectrum disorder and intellectual disability. Autism spectrum disorder and intellectual disability (ASD/ID) are severe neurodevelopmental conditions with early childhood onset. Advances in genetics have indicated that ASD/ID
  • Working from home on laptop at night
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    University Of Alabama At Birmingham

    Join us for a discussion moderated by Jean Ann Larson, Chief Leadership Development Officer at the University of Alabama at Birmingham Office of Leadership. This virtual event will highlight approaches to self-care while balancing social distancing with academic, scientific, and personal-life expectations. A panel of clinical and translational investigators spanning the bench to the community with

  • SHARe Logo

    SHARe is a 12-member consortium launched by the Center for Clinical and Translational Science to build on the strengths of our Partner Network to develop a truly transformational research enterprise in multisite studies for the Deep South.

  • Indiana University
    University Of Alabama At Birmingham
    National Institutes of Health
    Preclinical research involving animal models can be improved when appropriate experimental, analytical, and reporting practices are used. We produced a series of animated vignettes with quantitative experts and laboratory scientists discussing aspects of study design, interpretation, and reporting. Each vignette introduces viewers to key concepts that can stimulate the important conversations
  • What is CEREC? CEREC was established in 2016 to provide an outlet for obtaining external reviews for CTSA-funded pilot research and to minimize the likelihood of bias and conflicts of interest. CEREC also offers a larger pool of expertise from which to draw precisely matched reviews for scientific lines of inquiry that may not be well represented within the institution receiving the proposal. This
  • CCTS Translational Training Symposium
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    University Of Alabama At Birmingham
    The 2nd Annual CCTS Translational Training Symposium will convene predoctoral, postdoctoral, and early career scholars, as well as their mentors and training grant leaders, from across the CCTS Partner Network for experiential training and career development sessions on translational and design thinking, grant writing, clinical trials, community engagement and funding opportunities. The
  • CCTS Special  Modules poster v20190907-04
    University Of Alabama At Birmingham

    The Center for Clinical and Translational Science (CCTS; UAB Hub) is located in a region of the country heavily burdened by chronic diseases like obesity, diabetes, cancer, stroke and hypertension. The vision of the CCTS is to ameliorate disparities in these and other conditions that disproportionately affect our region, especially in underserved minority and special populations represented both

  • I-Corps: bridging biomedical innovation and the market (M. Wasko, PhD) Take a biomedical innovation from your research & learn how evaluate its commercial potential & successfully build a business model around your innovation; Develop a go-to market strategy; Qualify to participate in I-Corps Program (up to $50k in funding)
  • UAB/Children’s of Alabama/School of Health Professions (S. Buchalter, MD and L. Hayes, MD) Develop enhanced expertise and experience in quality improvement and patient safety methodology; Develop and Implement a quality improvement and or patient safety project applicable to the Scholar’s interests and care delivery environment
  • UAB/Children’s pediatric simulation center (N. Tofil, MD, MEd) Increase knowledge, hone skills, and practice teamwork in the context of real life patient scenarios; Understand the breadth of care scenarios that are applicable to simulation; Enhance ability to rapidly improve care provision
  • UAB Pharmacoepidemiology and Economic Research (PEER) Unit (M. Kilgore, PhD and J. Curtis, MD, MSPH, MS) Understand problems/limitations of administrative data & methods to minimize these problems; Specify & implement methods to validate claims-based algorithms, link claims to EMR data; Analyze data for a particular project and present results.
  • Center for AIDS Research (CFAR) Network of Integrated Clinical Systems (CNICS) (M. Mugavero, MD, MHSc) Learn benefits of CNICS’ integrated system of clinical/ behavioral/biological data versus other medical records; Understand how to successfully retrieve/critically evaluate/design study w/ CNICS data
  • Phase I clinical trials/public-private partnerships (M. Saleh, MD) Develop knowledge of clinical trial implementation, including feasibility & study design; Work w/ multidisciplinary team to fulfill project milestones; Learn the basic approaches to evaluate safety, to determine a safe dosage range, & to identify side effects.
  • Clinical Informatics / medical systems (J. Willig, MD) Learn how to collect structured data at the point of care; Learn how to export data to warehouse containing genomic and other biological information; Use data for CTR
  • Cochrane Musculoskeletal Review Group – US Cochrane Satellite focused on network meta-analysis (J. Singh, MD) Develop and refine research questions and analytic frameworks; Conduct literature review; Develop and test data abstraction forms; Learn methods of abstracting data into evidence tables; Develop summary tables and prepare synthesis reports
  • Alliance for Innovative Medical Technology (AIMTech)/medical device development (R. Hergenrother, PhD) Managing clinical trial and FDA approval processes; Market and user assessments; Steps towards establishing small companies, and how to raise venture capital for medical device development.