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Developing new therapies and getting them to patients is long and difficult. During public health emergencies, such as the Covid-19 Pandemic, science must move faster than ever. That is where translational science comes in. Translational science is focused on streamlining the process of moving (“translating”) lab findings into medical practice and treatments to improve health and well-being.
NCATS is supporting research activities spanning the translational science spectrum to address the novel coronavirus 2019 (SARS-CoV-2) and the disease it causes (COVID-19). To accelerate translational research, NCATS has developed research tools, technologies, expertise and collaborative networks that can quickly pivot to address urgent public health issues.
The COVID-19 pandemic continues to present considerable public health challenges in the United States and around the globe. One of the most puzzling is why many people who get over an initial and often relatively mild COVID illness later develop new and potentially debilitating symptoms. These symptoms run the gamut including fatigue, shortness of breath, brain fog, anxiety, and gastrointestinal
A large randomized, placebo-controlled clinical trial led by the National Institutes of Health shows that treating adults hospitalized with COVID-19 with infliximab or abatacept — drugs widely used to treat certain autoimmune diseases — did not significantly shorten time to recovery but did substantially improve clinical status and reduce deaths. Some COVID-19 patients experience an immune
SDoH are the non-clinical covariates of how people live, grow, learn and age and relates to how people manage stressors or prevent worsening health outcomes. Progressively, data about patient-level SDoH are collected using clinical screening tools for social needs and social risk factors. CD2H has led multiple SDoH synergistic initiatives relating to overall improvement of SDoH encoding and
In this seminar, Mary Frecker, PhD, and Greg Lewis, PhD, director and associate director of Penn State Center for Biodevices, will describe the Center’s approach toward fostering multidisciplinary research collaborations and the recommendations of a University-wide panel they have hosted on this topic. This seminar is for researchers interested in learning about cross-campus interdisciplinary
Washington University School of Medicine in St. Louis has received a $61 million grant from the National Center for Advancing Translational Sciences of the National Institutes of Health (NIH) to support the infrastructure for developing and carrying out biomedical research studies. The funding supports Washington University’s Institute of Clinical and Translational Sciences (ICTS), which was
As COVID-19 vaccines are approved for pediatric populations, a cross-collaborative effort between the USC School of Cinematic Arts, the Annenberg School for Communication and Journalism, and the Keck School of Medicine seeks to highlight the importance of getting vaccinated to protect yourself and your family. This successful collaboration resulted in the creation, production and dissemination of
Assefa, a recent graduate of UVA, participated in the UVA-Historically Black Colleges and Universities Summer Research Bridge to Data Science program (Bridge) as a research fellow. This program is co-sponsored by integrated Translational Health Research Institute of Virginia (iTHRIV), the UVA School of Data Science (UVA SDS), Oracle, and Deloitte. According to the UVA SDS, the UVA-HBCU Summer
Since 2007, the Institute of Translational Health Sciences (ITHS) has partnered with the University of Washington (UW), Fred Hutchinson Cancer Research Center, and Seattle Children’s on a Clinical and Translational Science Award (CTSA). This hub serves a large five-state region—Washington, Wyoming, Alaska, Montana, and Idaho (WWAMI)—encompassing rural and urban communities with unique health
Registration is now open for the 5th Annual Children's National Hospital - NIAD Symposium! The two-day hybrid symposium will feature current research related to COVID-19 and Autoinflammatory/Neuroimmune. All are invited to attend! This annual symposium celebrates the partnership between Children’s National Hospital and the National Institute of Allergy and Infectious Diseases (NIAID). Established
A University of Arkansas for Medical Sciences (UAMS) team’s article on COVID-19 vaccine hesitancy recently received the 2022 Clinical and Translational Science Award from the American Society for Clinical Pharmacology & Therapeutics (ASCPT). The study, “COVID-19 Vaccine Hesitancy: Race/Ethnicity, Trust and Fear,” became the most downloaded paper in 2021 from ASCPT’s journal Clinical and
The disruptions to social and economic life related to the COVID-19 pandemic have exacerbated factors known to elevate the risk of intimate partner violence (IPV) and created barriers to service availability for women currently experiencing it. This binational program of research comprised of scientists and community partners from Toronto, Chicago, and Miami helps address an ongoing need for
The Rapid Research Pilot Program (RP2) is designed to provide support for small, manageable research studies that focus on evaluating novel strategies for the implementation of COVID-19 testing in vulnerable and underserved populations. Researchers seeking funds to conduct COVID-19 testing can apply for up to $200,000 in direct cost funding and, if awarded, will have one year to complete the co
Vanderbilt University Medical Center has competed successfully for a third five-year renewal of its Clinical and Translational Science (UL1) Award by the National Center for Advancing Translational Sciences. Initially funded in 2007, the renewal will provide more than $73 million for another five years to support the Vanderbilt Institute for Clinical and Translational Research (VICTR) and its
Rochelle P. Walensky, MD, MPH, director of the Centers for Disease Control and Prevention (CDC), visited Washington University School of Medicine to discuss lessons learned from the COVID-19 pandemic. As part of the Department of Medicine’s weekly Grand Rounds series, she sat down with ICTS Director William G. Powderly, MD for a discussion that highlighted the pandemic’s success stories and
Public health experts report that members of immigrant and refugee communities continue to be disproportionately affected by the COVID-19 pandemic, with higher rates of infection and death. Health disparities can be associated with job type, immigration status and English proficiency. A team of Mayo Clinic medical experts and community leaders collaborated to find ways to reduce health disparities
The National Institutes of Health (NIH) has invested nearly $470 million to build a national study population of diverse research volunteers and support large-scale studies on the long-term effects of COVID-19. The Colorado Clinical and Translational Sciences Institute (CCTSI) is playing a major role in the initiative called REsearching COVID to Enhance Recovery or RECOVER. Many of us know someone
A new article by researchers at the Medical University of South Carolina (MUSC) and Clemson University in the Journal of Medical Internet Research (JMIR) Research Protocols provides a roadmap for implementing an exposure notification mobile app among students, faculty and staff at Clemson, a large public university in South Carolina. The roadmap also provides a theory-based framework for
Insights to Inspire 2022: In Our Own Words is a collection of Program Summaries from across the consortium for the Careers in Clinical & Translational Research (CCTR) metric. From 36 unique hubs come insights into how hubs are working to improve the experiences of their KL2 scholars and TL1 trainees. Starting in December 2021 and extending through April 2022, In Our Own Words will feature one of