N3C
Columbia University
The mission of the Irving Institute for Clinical and Translational Research is to advance discoveries, knowledge, and innovation to improve human health across the lifespan for diverse populations in upper Manhattan and around the world. By mobilizing and connecting Columbia University’s researchers, we aim to create a seamless integration of community and academic partnerships. Our commitment to train a multi-faceted workforce, provide vital resources to researchers, and improve the efficiency of research processes, promotes the collaborative team science framework needed to translate research discoveries into effective interventions that address current and future health concerns.
We provide over 70 different services and programs focused on education and training, seed funding, bioinformatics, biostatistics, clinical research, lifespan research and special populations, regulatory knowledge and bioethics, an off-site community facility and health informatics websites.
May 30, 2023The N3Connect Bulletin aims to inform, connect, and engage members of the N3C community. The bulletin includes updates on community events, news, important announcements, and opportunities for involvement, as well as stories and profiles about N3C community members and their achievements. To join the N3Connect Bulletin mailing list, please visit https://bit.ly/JoinN3Connect
May 22, 2023The White House Office of Science and Technology Policy (OSTP) released comprehensive new recommendations to promote user data privacy for both public and private sector entities, focusing on mitigating bias and maximizing efficiency in an equitable way. The “National Strategy to Advance Privacy-Preserving Data Sharing and Analytics1” establishes clear objectives to aid the research, development
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April 27, 2023
The N3Connect Bulletin aims to inform, connect, and engage members of the N3C community. The bulletin includes updates on community events, news, important announcements, and opportunities for involvement, as well as stories and profiles about N3C community members and their achievements. To join the N3Connect Bulletin mailing list, please visit https://bit.ly/JoinN3Connect
April 10, 2023The National COVID Cohort Collaborative (N3C) is an initiative launched by NIH/NCATS in response to the COVID-19 pandemic. Its main aim is to accelerate scientific discovery and provide a tool for collaboration on COVID-19 research by creating an aggregated and harmonized repository of electronic health record (EHR) data from COVID-19 patients across the country. This data enclave represents one
-Center for Data to HealthArtificial Intelligence and other Data Science approaches have shown the potential to transform healthcare in recent years. Novel algorithms can now improve the interpretation of images, expedite diagnoses, suggest medications, and predict the development of diseases or complications. Availability of cancer-related diverse data sets including EHR, Genomics, PROs, Claims, Wearable, Imaging via the
-Center for Data to HealthOver the past year, N3C's Data Ingestion & Harmonization Team has developed two scorecards that will be sent to all 77 released sites on a biweekly basis. The site-specific scorecard will return data quality metrics and feedback for the individual site while the site comparison scorecard will return data quality metrics and feedback of that site compared to the rest of the sites in either the OMOP
Center for Data to HealthNCATSA National CTSA Coordinating Center that established a foundation to provide access to medical record data, innovative tools, and a diverse group of researchers are foundational to achieve equity through the science of translation! The CTSA Community has created a number of innovative resources to facilitate national coordination of translational research and enable health equity, diversity and
-Center for Data to HealthDr. Melissa Haendel and Dr. Jakob Seidlitz will present "2022 DataWorks! Grand Prize Winners: Innovations in Data Sharing and Reuse" at the monthly Data Sharing and Reuse Seminar on March 10, 2023 at 12 p.m. EDT.
November 30, 2022Through a generous grant from Assistant Secretary for Planning and Evaluation (ASPE) OS-Patient-Centered Outcomes Research Trust Fund (OS-PCORTF), National COVID Cohort Collaborative, N3C is pleased to announce the inclusion of de-identified linked CMS Medicare data to the existing 19 billion rows of mortality, viral variant, and clinical data in the Enclave. The addition of CMS Medicare data is-
-Center for Data to Health
The N3Community Forum is a place to learn about new COVID-related studies, papers, and opportunities. This event is held on a weekly basis and features one to two presentations from members of the N3C community on selected topics regarding their work with N3C. Each presentation is followed by a discussion session open to participants. Monday, October 31, 2022 at 2pm-3pm PT / 5pm-6pm ET 1st Topic
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-Center for Data to HealthThe N3Community Forum is a place to learn about new COVID-related studies, papers, and opportunities. This event is held on a weekly basis and features one to two presentations from members of the N3C community on selected topics regarding their work with N3C. Each presentation is followed by a discussion session open to participants. Monday, November 14, 2022 at 2pm-3pm PT / 5pm-6pm ET with Sula
June 27, 2022Researchers across the country gathered virtually earlier this month to dive into the ever growing pool of big data at the two-day Un-Meeting event, “Making Real-World Data and Real-World Evidence a Reality for Translational Science.”
May 26, 2022SDoH are the non-clinical covariates of how people live, grow, learn and age and relates to how people manage stressors or prevent worsening health outcomes. Progressively, data about patient-level SDoH are collected using clinical screening tools for social needs and social risk factors. CD2H has led multiple SDoH synergistic initiatives relating to overall improvement of SDoH encoding and
March 30, 2022The National Center for Data to Health’s National COVID Cohort Collaborative (N3C) Data Enclave houses the largest repository of COVID-19 data in the United States, with more than 4.5 million COVID+ patients. The N3C Data Enclave contains harmonized clinical data provided by more than 70 contributing health care institutions and consists of more than 14 billion rows of clinical information. The
December 01, 2021Organ transplant recipients and people living with HIV are more likely to experience adverse effects after contracting COVID-19. And kidney and heart transplant recipients are at highest risk. Those are just some of the conclusions coming from an international team of researchers that includes Virginia Commonwealth University data scientists. Amy Olex, M.S., and Evan French of the Wright CenterBackground and Aims In patients with chronic liver diseases (CLD) with or without cirrhosis, existing data on the risk of adverse outcomes with SARS-CoV-2 infection have been mixed or have limited generalizability.
- Journal of Clinical Oncology
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May 26, 2021If you missed the webinar on Weds May 13th presented by Kenneth Gersing, MD, Director of Informatics NCATS DCI entitled Studying COVID-19 Using Real-World Data: Lessons Learned and Steps Forward After One Year of the National COVID Cohort Collaborative (N3C), you can now access the recording. Topics include: • Lessons learned after one year of studying COVID-19 using real-world data • Future
-Center for Data to HealthNoha Sharafeldin, MBBCh, MSc, PhD co-leads the Oncology Domain Team of the National COVID Cohort Collaborative (N3C). Dr. Sharafeldin will present the abstract titled: Outcomes of COVID-19 in Cancer Patients: Report From the National COVID Cohort Collaborative (N3C) at the American Society of Clinical Oncology (ASCO) annual meeting. The oral abstract is part of the Care Delivery and Regulatory-
May 06, 2021For the past year, researchers have been pursuing possibilities for the repurposing of existing drugs that can effectively disrupt COVID-19 disease processes. Electronic health record (EHR) data from the N3C Data Enclave were used to produce a recent preprint published in medRxiv on April 6, 2021 titled Drug repositioning candidates identified using in-silico quasi-quantum molecular simulation
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Center for Data to Health
The attached files are provided to the CTSA Program Communications team for use in promoting and communication about the N3C.
The attached doc is guidance for how our hub partners should communicate about N3C efforts
-Center for Data to HealthFinding the right dataset can sometimes be a challenge in data science. A new initiative will provide Penn State researchers with access to a trove of COVID-19 data, updated frequently by health care systems around the United States. Penn State faculty can learn how to get access to the database and what data is included at a Data Science Community talk at 1 p.m. on Thursday, April 15. Advance-
April 07, 2021
Read the latest N3C preprint now published in medRxiv by authors: Joy Alamgir, Masanao Yajima, Rosa Ergas, Xinci Chen, Nicholas Hill, Naved Munir, Mohsan Saeed, Kenneth Gersing, Melissa Haendel, Christopher Chute, Ruhul Abid. Background: Drug repositioning is a key component of COVID-19 pandemic response, through identification of existing drugs that can effectively disrupt COVID-19 disease
March 05, 2021Melissa A. Haendel, PhD, has been named Chief Research Informatics Officer (CRIO) for the University of Colorado Anschutz Medical Campus, a newly created position responsible for transforming the campus use of information and information systems to accelerate biomedical discoveries, streamline health system operations, and continuously improve patient care. The CRIO office will lead efforts to
February 11, 2021NCATS has provided the FDA with access to the N3C Data Enclave. FDA investigators interested in accessing N3C COVID-19 data must complete appropriate human subjects and NIH security training, review and abide by NCATS technology transfer requirements, and submit a Data Use Request (DUR) detailing their proposed project and use of N3C data. For details on how FDA investigators can access the N3C
February 05, 2021Researchers have been anxious to learn what variables describe the COVID-19 patient cohort. Using the harmonized data in the N3C Data Enclave from 39 institutions’ electronic health records around the country, collaborators were able to distill this information in the manuscript titled The National COVID Cohort Collaborative: Clinical Characterization and Early Severity Prediction and is now-
February 04, 2021N3C held the first Enclave orientation sessions on February 2nd and 9th to engage users of all types with learning to use the N3C Data Enclave. The sessions were conducted by N3C Training Coordinator Shawn O’Neil and had over 100 participants for each session in attendance. This two-part training course will repeat on an ongoing basis, alternating week by week. To view training information and
