HealthBest NR Supplement Reviews 2024: Benefits, Dosage, Price & Side Effects -...

Best NR Supplement Reviews 2024: Benefits, Dosage, Price & Side Effects – Our Top 5 Anti-Aging Support Products Review

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We personally test every product in our reviews and guides and create each post without any external influence. By ordering products anonymously and using independent testers, we gain first-hand experience and provide data-driven recommendations. If you use the links we provide to purchase products, we receive a commission as an affiliate. Learn more.

Are you looking for the best NR supplement to promote optimal longevity and support elite anti-aging benefits? If so, you’ve come to the right place.

We’ve examined the NR supplement market by studying ingredient lists, reading related clinical studies, comparing manufacturer satisfaction guarantees, quantifying price-to-value ratios, combing through user reviews, and more.

Through that process, we’ve identified 5 elite dietary products that utilize NR (nicotinamide riboside) for anti-aging support, aiding in the enrichment of lifespan and mitigation of age-induced health decline.

   Best Product
 Wonderfeel Youngr Acitaved NMN Supplement Image TablepartiQlar Pure NR Image TableGenuinePurity NR Supplement Image Table
ProductWonderfeel Youngr
EffectsMore power
 More energy
Skin elasticity
More power
Better health
More strenght
DNA health
Cellular regeneration
98 % pure
Side Effects
✓ NO side effects✓ NO side effectsNO side effects
Content60 capsules60 capsules60 capsules
Dosage2 capsules daily1 capsule daily2 capsules daily
Enough for
30 days60 days30 days
Price88,00 USD
47,99 USD
59,95 USD
 Buy nowBuy nowBuy now

The 5 Best NR Supplement Products

Our picks for the best NR supplement options are:

#1 Genuine Purity Liposomal NR – Best NR Supplement Overall (Elite NAD+ Support)
#2 PartiQlar – Best Pure β-NR Supplement
#3 Wonderfeel® Youngr™ NMN – Highest Quality NMN With Resveratrol
#4 Lovita NR – Best NR Supplement With Resveratrol
#5 Health Thru Nutrition NR – Best NR Supplement With PQQ

With its highly absorbable, highly pure NR molecules, we’ve determined the breakthrough dietary aid, Genuine Purity Liposomal NR, to be the best NR supplement that should provide top-notch anti-aging benefits for most users.

We’ll dive deeply into precisely why Genuine Purity Liposomal NR is the best NR supplement and give you a thorough review of all 5 products on our list below.

#1 Genuine Purity Liposomal NR—Best Overall Supplement (Elite NAD+ Support)

Test Winner #1
Product details:

  • Promotes cellular regeneration
  • Improves mitochondrial function
  • 98 % pure nicotinamide riboside
  • Price: 59,95 USD
  • Rating: ⭐⭐⭐⭐⭐

Taking the top spot and the clear choice for the best NR supplement, Genuine Purity Liposomal NR provides highly pure NR molecules (99% purity) enhanced with a liposomal protection system that should deliver you elite longevity and anti-aging benefits.

Genuine Purity Liposomal NR can support:

  • Greater Energy Production
  • Enhanced DNA Mending
  • Improved Immune Wellness
  • A More Efficient Metabolism
  • Boosted Cellular Repair
  • More Restful Sleep

Suppose you’re feeling “beaten down” or hampered by getting older. In that case, it’s evident that Genuine Purity Liposomal NR could be advantageous for you and maybe even help you feel as much as 10-20 years younger.

All it takes is 2 pills per day, preferably with some food, to assist you in achieving some noticeable results in just 4-6 weeks and more impressive benefits in time with continuous use.

Genuine Purity Liposomal NR High-Level Advantages

Genuine Purity Liposomal NR offers several high-level advantages, making it a premiere longevity-promoting choice and the best NR supplement on the market.

These include:

1. Using Highly Pure, Third-Party Authenticated NR Molecules

Each Genuine Purity Liposomal NR pill contains a research-supported serving of highly pure (99% pure) nicotinamide riboside sourced from elite means.

Plus, the nicotinamide riboside in Genuine Purity Liposomal NR has been third-party tested and authenticated for 99% purity, the gold standard in NR supplementation.

NR purity is always going to be a vital factor in the success of an NR supplement, and Genuine Purity Liposomal NR certainly “knocks it out of the park.”

2. Liposomal Encapsulation Promotes Elite Absorbability

Historically, NR supplementation has been hindered by a major obstacle—nicotinamide riboside doesn’t absorb especially well in humans.

Genuine Purity Liposomal NR seeks to solve this issue by encapsulating all of its NR molecules in lipid-based oval-shaped encasements that protect NR from corrosive gastrointestinal acids and digestive enzymes.

Known as “liposomal encapsulation,” this advanced system should allow you to absorb significantly more nutritional value from the highly pure nicotinamide riboside in Genuine Purity Liposomal NR.

3. Reputable Manufacturer With 20+ Years’ Experience

Genuine Purity Liposomal NR is manufactured in cGMP-certified facilities in the United States of America, adhering to the strictest safety standards in the industry.

Additionally, it was developed and is still manufactured by a health supplement producer with more than 20 years of experience building elite dietary aids.

You can rest assured you’re getting a consistently high-quality product each and every time you use Genuine Purity Liposomal NR.

Many qualities suggest Genuine Purity Liposomal NR is the best NR supplement on the market right now. Chief among them would be the elite NR purity, the liposomal protection system, and the manufacturer’s sterling reputation, which has been built over many years.

Genuine Purity Liposomal NR User Reviews

Men and women worldwide have experienced the impressive anti-aging support of Genuine Purity Liposomal NR, helping them to enjoy a more vigorous, highly fulfilling life for years and years after their so-called “primes.”

Here’s what a few Genuine Purity Liposomal NR users said about their experience:

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Dorothy Jensen After using Genuine Purity Liposomal NR for about 2 months, I already feel much better than I have in years. I’ve noticed more energy, reduced brain fog, and a greater ability to focus all day long. I recommend this supplement to all my friends.
Like · Answers · 4 Day(s)
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from Peter W.
on January 22, 2024

I’ve always been diligent about being healthy and staying in good shape. Yet, once I reached my 40s, that became increasingly difficult. A gym buddy actually told me about Genuine Purity Liposomal NR. It’s really helped me to keep in good physical condition and get in the gym every day.

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Re: Does anyone know Genuine Purity NMN?

Genuine Purity Liposomal NR is the best supplement I’ve ever used. It only takes a couple of capsules a day to help trigger awesome benefits. I’ve lost several pounds of fat, feel much better physically, and am definitely more mentally sharp than I was before trying this NR supplement.

  • Contribution from 29.01.2024 – 17:35

  • Author:


Almost all Genuine Purity Liposomal NR user reviews we encountered sounded similar. Many people spoke about how much vibrancy and energy the best NR supplement has assisted them in achieving.

Genuine Purity Liposomal NR Satisfaction Guarantee

Your Genuine Purity Liposomal NR order comes with a generous money-back satisfaction guarantee.

It’s so great that it allows you to try the best NR supplement for up to 90 days before applying for a refund of the purchase price if you’re unhappy with the results.

Another way of looking at it is that you’ll get a “free 90-day trial” with Genuine Purity Liposomal NR. If it doesn’t work for you, simply send back all the packaging to receive a refund of the purchase price for all used and unused products.

Where To Order Genuine Purity Liposomal NR

We’d recommend ordering Genuine Purity Liposomal NR from the manufacturer’s official webpage.

You’ll find the lowest prices there, including significant savings on bulk orders. Furthermore, they offer free shipping on all orders within the continental USA.

#2 PartiQlar - Best Pure Supplement

PartiQlar NR
Second #2
Product details:

  • Promotes metabolic health
  • Supports healthy aging
  • Improves cognitive function
  • Price: 47,99 USD
  • Rating: ⭐⭐⭐⭐⭐

What sets PartiQlar apart is its commitment to strict manufacturing standards. Its products are meticulously manufactured in cGMP-certified and FDA-compliant facilities, underscoring the brand’s dedication to safety and efficacy. In addition, PartiQlar’s Pure NR supplement holds the prestigious NSF certification for sports enthusiasts and adheres to a vegan-friendly, artificial colour-free, allergen-free and GMO-free formulation.

Pure Nicotinamide Riboside NR can help you to:

  • Improved energy metabolism
  • Improved cognitive function
  • Optimal exercise performance
  • Support metabolic health
  • Support healthy ageing
  • Maintain cardiovascular health

For those considering a daily dose, PartiQlar recommends a single capsule per day, providing 350mg of NR. While the supplement label may not explicitly state the form of NR, third party testing confirms the use of nicotinamide riboside chloride in this well-respected product.

partiQlar Nicotinamide Riboside NR High-Level Advantages

PartiQlar NR stands out as a compelling choice among NR supplements, offering several high-level benefits that firmly establish its position as one of the best options available on the market.

1. Affordable Pricing

PartiQlar offers a budget-friendly option for those seeking nicotinamide riboside NR supplementation.

2. NSF Certification For Sports

The product is proudly NSF certified, making it a trusted choice for sports enthusiasts, ensuring its safety and quality standards.

3. Exceptional Purity

PartiQlar’s Nicotinamide Riboside NR boasts an impressive 98% purity level, underlining the company’s commitment to delivering a high quality product.

4. Generous Multi-Buy Discounts

PartiQlar offers substantial discounts through multi-buy options, making it even more attractive to those considering long-term use.

partiQlar NR User Reviews

Users worldwide, of both sexes, have reported significant benefits from PartiQlar NR’s remarkable anti-aging properties, enabling them to enjoy a more vibrant, fulfilling lifestyle, brimming with vitality long past their perceived peak.

Here are some personal insights from PartiQlar NR customers:

avatar small
Thomas Morrison Great product. I have significantly more energy since I have been using partiQlar NR.
Like · Answers · 11 Day(s)
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from Eve
on January 28, 2024

I started taking PartiQlar NR a few weeks ago and am now starting to notice real changes. My sleep has improved significantly, I sleep soundly and wake up feeling refreshed. In general, I feel much better since I started taking the capsules! Amazing!

Nicht hilfreich

Re: What are your experiences with partiQlar NR?

I have already tested several Partiqlar products and have always been convinced. This also applies to the NR capsules. They are well tolerated and easy to swallow. I was always very forgetful for a while, but this has improved since taking them.

  • Contribution from 03.02.2024 – 12:16

  • Author:


The overwhelming consensus among partiQlar NR reviewers is its profound effect on vitality and energy levels, which is reflected in numerous testimonials.

partiQlar NR Satisfaction Guarantee

Your purchase comes with a generous 60-day money-back guarantee. This gives you plenty of time to assess its effectiveness, essentially offering you a risk-free 60-day trial. If the results are not to your liking, simply return all packaging within the specified period and a full refund, covering both used and unused products, will be issued promptly.

Where To Order partiQlar NR

For the best service and prices, it’s best to purchase PartiQlar NR directly from the manufacturer’s official website. Not only will you benefit from competitive pricing, but you will also receive substantial discounts on bulk purchases. In addition, all orders over $50 within the contiguous United States are eligible for free shipping.

#3 Wonderfeel Youngr - Best NMN Supplement

Wonderfeel Youngr NMN
Third #3
Product details:

  • More power & energy
  • Improves skin elasticity
  • Money-back-guarantee
  • Price: 88,00 USD
  • Rating: ⭐⭐⭐⭐⭐

Wonderfeel Youngr NMN is emerging as the premier choice among NMN supplements for individuals seeking a potent blend of anti-aging ingredients. This prestigious brand combines 450 milligrams of NMN with 50 milligrams of trans-resveratrol, a combination acclaimed for its remarkable ability to significantly increase NAD levels. The symbiosis of NMN and resveratrol is a formidable force in supporting both cognitive performance and cardiovascular vitality.

Wonderfeel Youngr NMN can help you to:

  • Combat age-related weight gain
  • Alleviate cognitive fog, promoting clarity and improved cognitive function
  • Achieve deeper, more restorative sleep for optimal energy balance
  • Accelerate recovery after exercise
  • Improve skin suppleness
  • Reduce discomfort and soreness
  • Facilitate faster recovery from jet lag and hangovers

For those considering a daily regimen, Wonderfeel recommends a dosage of two capsules per day, providing a total of 900mg of NMN.

WonderFeel Youngr High-Level Advantages

1. Emphasis On Quality Ingredients

Youngr’s WonderFeel prides itself on the careful selection of its ingredients, boasting a range that includes essential elements such as Vitamin D, NMN (Nicotinamide Mononucleotide) and Trans-Resveratrol. These ingredients have been selected for their recognised benefits in supporting overall health and vitality. Each ingredient is rigorously tested to ensure maximum potency and efficacy, reflecting the brand’s commitment to formulation excellence.

2. Innovative Packaging

Upon initial purchase, customers are greeted with a refillable glass bottle that exemplifies Youngr’s commitment to sustainability and eco-conscious practices. This thoughtful approach not only minimises waste, but also adds a touch of sophistication to the product experience. Subsequent orders will be accompanied by eco-friendly refill pouches, carefully designed to reduce environmental impact while maintaining product integrity. This innovative packaging solution reinforces Youngr’s mission to provide wellness solutions that prioritise both consumer satisfaction and environmental stewardship.

3. Commitment To Quality Assurance

Youngr’s WonderFeel is manufactured in state-of-the-art cGMP (Current Good Manufacturing Practices) facilities, ensuring the highest standards of quality, safety and consistency. These facilities adhere to strict regulations and protocols, using the latest technology and rigorous quality control measures throughout the production process. By prioritising compliance with cGMP guidelines, Youngr guarantees that every batch of WonderFeel meets the highest standards of excellence, instilling confidence and peace of mind in its discerning clientele.

Wonderfeel Youngr User Reviews

Users of all genders from around the world have shared testimonials highlighting the remarkable anti-aging effects of WonderFeel Youngr.

Here are some personal accounts from satisfied customers:

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Sophie Lynch I started taking Wonderfeel about two months ago because I was increasingly struggling with sleep problems. For the last three to four weeks, I've been falling asleep within 10 minutes and waking up in the morning refreshed and uninterrupted. That is a huge difference. I finally have energy again.
Like · Answers · 13 Day(s)
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from Jacks
on January 17, 2024

I am now 43 years old, enjoy doing all kinds of sports, but am beginning to realize that I am no longer as fit as I was when I was 18 and have therefore ordered Wonderfeel Youngr. I've been taking it for about 6 weeks now and have noticed significant changes. My stamina has improved and I am much more efficient again. I can now do 4-5 sporting activities a week again without any problems.

Nicht hilfreich

Re: Does anyone know the NMN from Wonderfeel Youngr?

Excellent product. It is super easy for my stomach to take. Thanks to Wonderfeel I finally have more energy again and my memory has improved. I am really pleased with the results so far and will continue to take the capsules.

  • Contribution from 05.02.2024 – 16:39

  • Author:


The consensus of WonderFeel Youngr reviewers overwhelmingly emphasises its profound effect on memory enhancement, increased energy levels and improved sleep quality.

Wonderfeel Youngr Satisfaction Guarantee

Unfortunately, WonderFeel Youngr does not currently offer a satisfaction guarantee to its customers.

Where To Order Wonderfeel Youngr

For the best service and price, it is recommended to purchase WonderFeel Youngr directly from the manufacturer’s official website. This allows customers to take advantage of competitive pricing and exclusive discounts, ensuring a seamless purchasing experience.

#4 Lovita NR—Best NR Supplement With Resveratrol

Currently not recommended by us #4
Product details:

  • Boost NAD+ levels
  • Anti-Aging
  • Only a few customer reviews
  • Price: 34,99 USD

Ranking as the fourth-best NR supplement, Lovita NR combines suitable, reliably pure NR molecules with a couple of additional compounds, like resveratrol, to promote anti-aging and longevity benefits.

Lovita NR is designed to support:

  • Improved Sleep Quality
  • Boosted DNA Repair
  • Metabolic Enhancements
  • Enhanced Cellular Wellness
  • Reduced Occurrence Of Fatigue

If you’re dealing with many of the typical troubling issues that accompany aging, Lovita NR could be a good option to help you restore at least some of your youthful sprightliness.

All you’ll need to do is take 1 pill per day, ideally at the same time every day, to help you look, feel, and think more like you did in your 20s. Some benefits may appear in about 4-6 weeks. However, like all the best NR supplement options, continuous daily use is necessary to maintain long-term longevity and anti-aging benefits.

Lovita NR High-Level Advantages

Lovita NR comes with a few high-level advantages that firmly put it in the conversation for being one of the best NR supplement choices available.

These include:

1. Utilizing Good, Third-Party Authenticated NR Compounds

Every time you ingest Lovita NR, you’ll be feeding your cells with reliably good NR compounds that a third party has authenticated.

This is generally considered a “must-have” feature for an NR supplement to be considered elite.

Many subpar NR supplements use low-quality NR that isn’t third-party authenticated and may be ineffective. However, this isn’t an issue with Lovita NR.

2. Contains Excellent Ancillary Ingredients (Resveratrol & Betaine)

Lovita NR provides good NR molecules that can help you live a more vigorous life with greater longevity and also adds a pair of excellent ancillary ingredients that work cohesively to improve the overall formula.

The first is resveratrol, a compound found in the skin of red grapes known for aiding in reducing the buildup of oxidative stress and inflammation, both of which contribute to age-related decline at a cellular level.

The second is betaine, a compound highly concentrated in some foods like beets and spinach, and can help promote circulatory wellness, as well as mood and cognitive capacity.

As you see, there are multiple reasons to indicate that Lovita NR is among the best NR supplement options money can buy. The third-party tested NR, along with the additional high-quality anti-aging support ingredients, suggest great outcomes are possible.

Lovita NR User Reviews

Many women and men have raved about the longevity and anti-aging enhancements Lovita NR has helped bring them. It appears scores of individuals are living with more vitality thanks to the assistance of this NR supplement.

Here’s what a few Lovita NR users mentioned about their experience:

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Robert Clark Lovita NR is a great NR supplement. I’m 67, and I’ve struggled with age-related problems for many years. However, after using Lovita NR for a few months, I feel far more energetic and with it, so to speak. This stuff is helping me quite a lot.
Like · Answers · 16 Day(s)
avatar small
from Linda
on January 30, 2024

I’ve been using Lovita NR for almost a year, and let me tell you, it definitely helps. I’ve gotten back into my workout routine, dropped a few pounds, and just feel healthier than I did before. I’d suggest all women my age (65) use this product.

Nicht hilfreich

Re: What do you think of the NR supplement from Lovita?

Lovita NR is my go-to daily supplement. A friend recommended it to me, and she’s a sharp cookie, so I gave it a try. I have to thank her every day because this stuff has seriously helped me feel 20 years younger. It’s great.

  • Contribution from 01.02.2024 – 23:44

  • Author:


Nearly every Lovita NR user review we came across sounded similar to these. Most people discussed how the second-best NR supplement had helped restore much of the vitality that had evaded them with age. However, compared to the top 3 NR products in our comparison, we still have too few customer reviews to be 100% convinced.

Lovita NR Satisfaction Guarantee

Unfortunately, Lovita NR does not appear to have a satisfaction guarantee at this time.

Where To Order Lovita NR

We found the best prices for Lovita NR on Amazon. They also offer a 10-15% discount on all Lovita NR orders if you sign up for recurring monthly purchases.

#5 Health Thru Nutrition NR—Best NR Supplement With PQQ

Health Thru
Currently not recommended by us #5
Product details:

  • Elevates NAD+ levels
  • Revitalizing cellular energy
  • Only a few customer reviews
  • Price: 39,95 USD

Our fifth-best NR supplement is Health Thru Nutrition NR, a solid NR supplement that also includes PQQ (pyrroloquinoline quinone), an ancillary ingredient, and a micronutrient with some impressive anti-aging support benefits.

Health Thru Nutrition NR is formulated to support:

  • Improved Blood Flow
  • More Restful Sleep
  • Greater Muscle Performance
  • Enhanced Daily Energy Levels
  • Better Long-Term Cognitive Performance

As with many of the best NR supplement options, Health Thru Nutrition NR can help boost elements of longevity and support better aging outcomes, like those seen here.

Taking 2 Health Thru Nutrition NR capsules daily is recommended to potentially notice some benefits in approximately 4-6 weeks. However, as we’ve stated with all the best NR supplement products, continuous usage over the long run is necessary to get assistance in achieving optimal long-term benefits.

Health Thru Nutrition NR High-Level Advantages

There are numerous reasons to believe Health Thru Nutrition NR should rank among the best NR supplements on the market.

These include:

1. Contains Proprietary, Third-Party Tested NR Molecules

Health Thru Nutrition NR is designed with a proprietary form of NR (nicotinamide riboside) they call RejuvNR. This unique NR form, created by the in-house team at Health Thru Nutrition, has been tested and authenticated by a third party. Therefore, it’s been deemed to be of good quality and sufficient purity. Plus, it has no known negative side effects.

2. Utilizes PQQ (Pyrroloquinoline Quinone) For Additional Support

PQQ, or pyrroloquinoline quinone, is a chemical compound that assists in several enzymatic reactions in the human body, including some vital to supporting energy levels and metabolic wellness.

PQQ works in tandem with the proprietary NR molecules in Health Thru Nutrition NR to boost elements of cellular wellness and promote overall longevity. While it’s not quite Nicotinamide Riboside, PQQ is still a solid anti-aging compound that should deliver more benefits or at least help promote the benefits supported by NR.

The proprietary NR, RejuvNR, has been third-party authenticated. Plus, you’ll get a reliable serving or PQQ in Health Thru Nutrition NR. For those reasons, Health Thru Nutrition NR deserves to be ranked among the best NR supplement choices.

Health Thru Nutrition NR User Reviews

It appears more and more men and women are getting on board the Health Thru Nutrition NR train, often speaking highly of the impressive longevity and anti-aging outcomes it’s assisted them in experiencing.

Here’s what a few Health Thru Nutrition NR users said about their experience:

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Floyd Vargas Health Thru Nutrition NR helps me to feel younger, and live life with more positive energy. I had been seriously down in the dumps and struggling before finding this NR supplement. However, once I started using it, everything began to change for the better. I highly recommend it.
Like · Answers · 5 Day(s)
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from Janicee61
on February 02, 2024

I love Health Thru Nutrition NR. Seriously, this is my number one supplement because it supports my life force by improving my energy, supporting mental strength, and helping me wake up feeling refreshed every morning. All ladies around my age (61) should check it out.

Nicht hilfreich

Re: Does anyone have experience with NR from Health Thru?

I’ve tried a few anti-aging support supplements over the years, and this is my favorite. After a couple of months of using it daily, I noticed my body feeling stronger and my mind more limber. A few of my close friends even began using it after they saw the positive changes in my life.

  • Contribution from 13.01.2024 – 16:26

  • Author:

    Walter Knight

The reviews reflect the general consensus we have seen regarding Health Thru Nutrition NR. It seems that many Health Thru Nutrition NR users are quite happy with their results.But again, we need more customer reviews.

Health Thru Nutrition NR Satisfaction Guarantee

Health Thru Nutrition NR doesn’t allow you to use their NR supplement before deciding if it works for you. However, they do offer refunds of the purchase price if you return an unopened bottle within 60 days of purchasing.

Where To Order Health Thru Nutrition NR

We discovered the lowest prices for Health Thru Nutrition NR on Amazon. We’d recommend buying there, although large orders have no savings deals.

How Can The Best NR Supplement Help Enhance Longevity & Optimize Aging?

The best NR supplement options provide users with a research-supported serving size of NR (nicotinamide riboside) molecules. This natural compound is a precursor to a vital coenzyme known as NAD+.

In other words, when we ingest nicotinamide riboside or NR, our bodies organically convert those molecules into NAD+ through a series of enzymatic reactions.

The coenzyme NAD+ (nicotinamide adenine dinucleotide) plays a critical role in many biochemical reactions and physiological processes that power the human body, potentially impacting everything from daily energy levels to physical strength and cognitive capacity.

Research shows adequate NAD+ levels can help to:

  • Improve Sleep Quality
  • Boost Metabolic Efficiency
  • Support Enhanced Blood Flow
  • Support & Maintain Cognitive Wellness
  • Promote Strengthened Joint Health
  • Fuel Greater Physical Strength
  • Augment Immune System Wellness
  • Maximize Libido
  • Enhance Daily Moods
  • Amplify Daily Energy

However, as we age, we tend to lose a significant portion of the NAD+ that empowered us during our more youthful or “prime” years.

A clinical review published in Integrative Medicine: A Clinician’s Journal noted that by middle age, NAD+ levels will decline by more than 50% on average and that this decline is a significant contributor to why we experience much age-related deterioration.

The good news is that using the best NR supplement options may be the ideal way for us to support optimal NAD+ levels with no known negative side effects and no necessity for a prescription but plenty of potential anti-aging and longevity benefits.

Who Should Use The Best NR Supplement Options?

The best NR supplement options are designed to help women and men aged 18 and older. However, most NR supplement users are usually in their mid to late 30s or older. That’s because, typically, NAD+ levels begin a gradual, sometimes severe, decline once we’re approaching 40 years old or so. This decline can accelerate age-related issues like:

  • Slowing Metabolism
  • Degeneration Of Neurons
  • Reduced Cardiovascular Wellness
  • Accumulation Of Oxidative Stress
  • Increased DNA Damage

So, if you’re in your mid to late 30s or older and feel like the “ever-turning wheels of time” may be catching up with you, the best NR supplement options could help you feel, look, and think like a younger, more vibrant version of yourself. Even if you’re in your 20s and are simply concerned about the aging process, the best NR supplements might also be a viable option for you. Just remember the best NR supplement options require daily use and should be used continuously to yield long-lasting benefits. Many users should see some benefits in approximately 4-6 weeks, but terminating use will cause those benefits to dissipate. If you’re new to using health supplements or have health concerns, consult a physician before starting a new supplement regimen.

Additional Ways You Can Support Greater NAD+ Levels

The best NR supplement products should be an excellent way for most people to maximize NAD+ levels. However, there are some additional practices we can all take up to ensure our NAD+ levels remain optimal.

These include:

1. Intermittent Fasting

Intermittent fasting, or restricting food intake to certain days or times of the day, has been reported to help boost NAD+ levels.

It’s believed that fasting, or calorie restriction, puts stress on cellular mechanisms and opens similar NAD+ production pathways to NR supplementation.

In recent years, more people have begun to utilize intermittent fasting, largely because of its potential anti-aging benefits.

If you’ve never tried fasting before, we’d encourage you to speak with an expert before beginning a fasting routine.

2. Exercising Often

Regular strenuous exercise, generally multiple times a week, can help activate enzymes that rely upon NAD+ to create the conditions necessary for the biochemical reactions they stimulate.

Thus, when you regularly exercise and put your muscles under healthy strain, your body may naturally respond by producing more NAD+.

Both aerobic and anaerobic exercises can help.

If you’re new to exercising, reach out to an expert to help you get started on a regimen that can help you maximize NAD+ synthesis.

3. Sleeping (Uninterrupted) 7-9 Hours Per Night

Emerging evidence suggests that inadequate or regularly interrupted sleep can wreak havoc on NAD+ levels.

Of course, this isn’t a huge surprise, as chronic sleep deprivation is associated with many health issues, including accelerated age-induced decline.

If you’re having trouble sleeping, try:

  • Keeping A Consistent Sleep Schedule
  • Keeping A Cool, Dark Sleeping Space
  • Lowering Your Caffeine Intake
  • Removing Electronics From Bed

These tips should help you get better, more restful sleep and subsequently promote greater NAD+ levels.

4. Eating A Nutrient-Dense Diet

Certain NAD+ precursors, like NR, can be found in food. However, the concentration of NR may vary wildly and often be too minimal to have much impact.

That said, regularly eating a nutrient-rich diet while avoiding processed foods, harmful fats, and excess sugar should help your body produce and regulate NAD+ more effectively.

Try eating more:

  • Turkey, Chicken, Fish
  • Spinach, Kale, Broccoli
  • Almonds, Peanuts, Sunflower Seeds
  • Mushrooms
  • Fermented Foods

These foods contain relatively high concentrations of NAD+ precursors and may help support greater NAD+ levels if eaten regularly.

5. Limiting Alcohol Consumption

When the body digests alcohol, it takes a sizable amount of NAD+ to produce the necessary enzymatic reactions.

In other words, every sip of alcohol we take requires using some of our NAD+ reserves to be used.

Over time, this can have a massive deteriorating effect.

Regularly utilizing these practices should help you produce more NAD+ or at least maintain current NAD+ levels into the future.

Ideally, you’d want to combine these “lifestyle practices” with the best NR supplement options to maximize NAD+ synthesis over the long run.

Of course, adhering to a strict health regimen can be difficult for many of us. The good news is that the best NR supplement products can help to make up the difference.

Frequently Asked Questions

Can NMN and NR supplements be used together?

There is no scientific evidence or official recommendation to support the simultaneous use of NR and NMN supplements. While some individuals may consider combining these precursors to supposedly increase NAD+ levels more efficiently, prudent supplementation emphasises moderation.

Is there a risk of adverse effects with high quality NR supplements?

Although NR supplements are generally considered safe to take, there are potential side effects. These include tingling sensations in the legs and toes, nausea, headaches, diarrhoea and itching, especially with excessive use or individual sensitivities.

What is the recommended daily dose of an NR supplement?

Some brands suggest a daily intake of 500mg of NR as a general guideline. Dosages used in research studies typically range from 250 to 1000 mg per day. Consultation with a healthcare professional is recommended to determine the appropriate dosage for your specific health needs.

Finding The Best NR Supplement Conclusion

As you know, aging can be a real pain. What were once minor issues tend to balloon into significant problems. We may feel substantially more exhausted, more unhappy, and more fed up with the difficulties we face on a daily basis.

Fortunately, emerging scientific studies are reporting that much of this age-induced deterioration can be linked to deteriorating NAD+ levels.

We live in a day and age where the best NR supplement options may be able to help correct what were previously thought to be uncorrectable issues.

So, we’d encourage you to choose the best NR supplement for you and start living life on your terms.


  1. „The Science Behind NMN–A Stable, Reliable NAD+Activator and Anti-Aging Molecule.“ PubMed. National Center for Biotechnology Information. Click for Details.
  2. „A randomized placebo-controlled clinical trial of nicotinamide riboside in obese men: safety, insulin-sensitivity, and lipid-mobilizing effects“. ScienceDirect. Click for Details.
  3. „Improvement of tissue‐specific distribution and biotransformation potential of nicotinamide mononucleotide in combination with ginsenosides or resveratrol.“ PubMed. National Center for Biotechnology Information. Click for Details.
  4. „Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice.“ PubMed. National Center for Biotechnology Information. Click for Details.
Paramedic & Registered Nurse at University of Florida

Stephen Esposito has 11 years of healthcare experience as both a Paramedic (NRP) and Registered Nurse (RN). He has worked in both ground and helicopter ambulance (CCP-C, CFRN), emergency room, ICU, primary care, specialty care, psychiatric, and wilderness medicine. He also practices and has a lifelong interest in preventative medicine.

In addition, he writes content marketing for the healthcare industry because that is where his expertise lies. He is a conscientious, research-driven writer who cares about deadlines, accuracy, and ethics.

Health Coach

Emily Johnson is an experienced digital health journalist and content creator who has covered a wide range of topics, including public health, medical cannabis, nutrition, and biomedical science for over a decade. Her mission is to empower and educate people by bringing health matters to life with engaging, evidence-based writing. Emily has experience in the healthcare industry as a researcher, clinical data manager, and clinical trial monitor.


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