HealthCan Creatine Increase Testosterone - What You Need To Know 2024

Can Creatine Increase Testosterone – What You Need To Know 2024

Creatine has long been a top choice among bodybuilding enthusiasts. Recently, its popularity has experienced a resurgence due to claims that creatine, in addition to its well-established support for strength and muscle growth, also has the potential to boost testosterone production. If this claim proves true, creatine could become an exceptional supplement.

However, if it falls short in this regard, it will still be an effective supplement, albeit one that doesn’t contribute to testosterone enhancement. In this article, we will explore the relationship between creatine and testosterone. Through our exploration, we aim to definitively determine whether incorporating a creatine supplement into your regimen can actually stimulate your body’s natural testosterone production.

Does Creatine Increase Testosterone?

While creatine is a popular supplement for improving athletic performance and muscle growth, it does not directly increase testosterone levels. Creatine primarily increases energy production in the muscles, which helps during short bursts of intense physical activity.

Testosterone, on the other hand, is a hormone produced by the body that plays a critical role in muscle development, among other functions. While some studies suggest a possible small effect of creatine on testosterone levels, the evidence remains inconclusive. To boost testosterone, focus on proper nutrition and exercise, and consult a healthcare professional for guidance.

What Does Creatine Do?

Creatine, an organic nitrogenous compound, occurs naturally in the human body and plays a vital role in energy metabolism. The body converts creatine to phosphocreatine, a readily available energy reservoir used to replenish adenosine triphosphate (ATP), the primary energy currency in cells. The need for ATP increases during vigorous physical activity. Taking a creatine supplement allows for the rapid restoration of this energy reserve, allowing for longer and more intense workouts.

Does Creatine Increase Testosterone?

The evidence regarding creatine’s potential to increase testosterone levels remains inconclusive. A single study conducted in 2006 reported a 22% increase in testosterone levels when creatine supplementation was combined with exercise. However, other research has failed to demonstrate statistically significant improvements in this regard. Therefore, the prevailing consensus is that creatine does not significantly affect testosterone levels.

It’s worth noting that creatine has been observed to increase dihydrotestosterone (DHT) levels, leading some to speculate that it may have a similar effect on testosterone. However, it’s important to recognize that DHT and testosterone are different hormones. DHT primarily plays a role in the development of hair and skin cells, not muscle tissue.

In addition, creatine has been shown to promote insulin-like growth factor-1 (IGF-1), which is associated with muscle growth. The aforementioned 2006 study examined the effects of testosterone supplementation on several factors, including hormone levels. In this study, thirty-three college football players were randomly assigned to one of three study groups:

  • Creatine supplementation
  • Creatine + beta-alanine supplementation
  • Placebo

All three groups participated in a strength training program over a ten-week study period. At the end of the study, the creatine group experienced a mean increase in free testosterone levels from 20.0 nmol/L to 24.4 nmol/L.

Where Did The Idea Of A Creatine-Testosterone Connection Come From?

The idea that creatine might play a role in increasing testosterone levels likely stems from its ability to potentially increase insulin-like growth factor-1 (IGF-1) and dihydrotestosterone (DHT). IGF-1, like testosterone, is a hormone critical for muscle growth, and there is limited research to suggest that creatine supplementation may contribute to increased IGF-1 production. This correlation has led to speculation that creatine may have a similar effect on testosterone.

DHT, on the other hand, is a sex hormone derived from testosterone. Some research has suggested that creatine supplementation may lead to elevated DHT levels. However, these studies have not shown a concomitant increase in testosterone levels. A few studies have suggested a possible association between creatine and a small increase in testosterone when combined with exercise. However, the reported increases in testosterone have been minimal, typically not exceeding 1.5 ng/mL.

What Is Creatine Used For?

Supplemental creatine serves four primary purposes:

  1. Enhanced strength and power: By replenishing ATP levels, creatine enables the potential for squeezing out additional repetitions towards the conclusion of a workout and generating increased explosive force.
  2. Augmented muscle mass: Creatine aids in elevating water content within muscle cells, resulting in an amplified muscle size. It also facilitates the stimulation of muscle protein synthesis.
  3. Heightened anaerobic capacity: Creatine serves as an optimal energy source for rapid, intense, and brief exercise sessions.
  4. Enhanced post-workout recovery: Creatine contributes to improved recovery by stimulating muscle glycogen synthesis and replenishing energy reserves.

Can Creatine Help Increase Testosterone Indirectly?

While it is generally accepted that creatine does not directly increase testosterone levels, there is some evidence that it may have an indirect effect through the following mechanisms:

Enhanced Training

Research has shown that creatine can enhance exercise performance, resulting in improved anaerobic endurance, allowing you to complete more repetitions with greater force. Studies indicate that increased training intensity is directly related to increased testosterone release. Creatine may also speed post-workout recovery by increasing muscle glycogen synthesis and replenishing energy.

Potential To Reduce Inflammation

Low testosterone levels have been linked to chronic inflammation, and creatine may have anti-inflammatory properties. This could potentially create an environment conducive to increasing testosterone production.

Other Benefits Of Creatine

Despite the questionable evidence surrounding creatine’s ability to increase testosterone levels, there are numerous other compelling reasons to consider adding this supplement to your routine, especially if you exercise regularly. Here are five compelling reasons to prioritize creatine as part of your supplement regimen.

Improves Cognitive Function

For optimal performance, the brain requires a significant amount of energy. Creatine supplementation can potentially increase ATP levels in the brain, providing an easily accessible energy source and facilitating proper energy metabolism in the brain. In addition, creatine may have neuroprotective properties. As an antioxidant and cell membrane stabilizer, it could help protect brain cells from oxidative stress and harmful substances.

This potential protective effect could help maintain brain health and reduce the risk of neurodegenerative disease. Several studies suggest that creatine supplementation may improve cognitive abilities such as short-term memory, reasoning, and IQ. In addition, creatine may affect the levels of certain neurotransmitters in the brain, including dopamine and serotonin.

These neurotransmitters play a key role in mood regulation, behavioral motivation, and maintenance of cognitive function. Finally, creatine may help regulate fluid levels within brain cells. Imbalances in brain fluid can lead to cellular swelling and impaired neural communication, underscoring the importance of maintaining optimal fluid balance for peak brain performance.

Enhances Athletic Performance

Creatine supplementation increases phosphocreatine levels in muscle cells. Phosphocreatine is used rapidly to restore ATP levels during high-intensity exercise such as weightlifting or sprinting. The addition of creatine contributes to the accelerated resynthesis of ATP by increasing phosphocreatine levels, providing an enhanced energy reserve for short bursts of intense physical activity.

Creatine has been shown to increase muscle strength, energy levels and power output. It can be instrumental for athletes seeking those crucial extra repetitions at the end of a set, which can have a significant impact on the athletic performance.

Better Recovery

During rigorous exercise, the body’s glycogen stores, the primary source of muscle fuel, are rapidly depleted. Creatine supplementation has been shown to accelerate the replenishment of muscle energy reserves by increasing the rate of glycogen resynthesis during the post-exercise recovery period. Intense physical activity can lead to muscle damage and inflammation. Creatine’s anti-inflammatory properties may help reduce muscle damage and inflammation after exercise.

In addition, creatine supplementation has been shown to increase muscle protein synthesis, a critical process for muscle recovery and repair. Increased skeletal muscle protein synthesis helps promote muscle growth and repair of damaged muscle fibers during the recovery period. Creatine exerts an osmotic effect on muscle cells, attracting water into them.

This helps maintain proper cellular hydration, which is essential for normal cellular function and overall recovery. Ultimately, creatine supplementation can improve an athlete’s ability to recover between sets by accelerating ATP replenishment and increasing energy availability.

Enhances Energy Production

Creatine is stored in the muscle as phosphocreatine (PCr). During periods of intense activity or strenuous muscle contraction, PCr plays a critical role in converting adenosine diphosphate (ADP) back into adenosine triphosphate (ATP). This process, known as the creatine phosphate system, facilitates the regeneration of ATP, the primary fuel source for muscle contractions. ATP serves as the “energy currency” of cells and is critical for various cellular functions, including muscle contraction.

As ATP loses its phosphate group and is converted to ADP during energy expenditure, creatine steps in by breaking down PCr and providing a phosphate group. This phosphate group accelerates the regeneration of ATP, resulting in increased energy production. This rapid availability of ATP ensures a readily available energy source for muscular contractions by allowing ADP to quickly combine with the phosphate group to regenerate ATP.

Facilitates Muscle Growth

Including creatine in the diet increases the presence of phosphocreatine (PCr) in muscle cells. PCr acts as a rapid energy reservoir for ATP replenishment during physical activity, a critical element for muscle contraction. Creatine supplementation increases ATP resynthesis and provides additional energy for intense exercise by increasing PCr levels.

This increased energy supply allows individuals to perform more vigorous exercise, complete additional repetitions, and lift heavier weights, all of which contribute to the development of muscle mass. Creatine supplementation can increase an individual’s training capacity, resulting in an increase in training volume. Increased training volume has been associated with gains in muscle mass.

Creatine causes muscle cells to retain more water, increasing intracellular fluid volume (cell volumization). This cellular swelling promotes an anabolic environment conducive to muscle protein synthesis, the process of building new muscle proteins. The increased cellular signaling triggered by increased fluid content may promote muscle protein synthesis and support muscle mass growth.

In addition, creatine supplementation may enhance anabolic signaling pathways that are critical for muscle development. Molecular pathways such as the mammalian target of rapamycin (mTOR), which are essential for stimulating muscle protein synthesis and muscle growth, have been shown to be activated by creatine supplementation.

Methods To Increase Testosterone Levels

Taking a creatine supplement may not be the most prudent approach if your specific goal is to increase testosterone levels. However, it may indirectly help by promoting more effective training sessions and recovery. Here are three alternative strategies that are more effective at boosting testosterone.


Hormone replacement therapy (HRT) is a medical procedure in which exogenous testosterone is administered to men with low “T” levels. This is done under medical supervision and is typically prescribed for individuals diagnosed with hypogonadism (low testosterone levels). HRT can be administered by several methods:

  • Transdermal patches
  • Topical gels
  • Injections
  • Buccal tablets
  • Subcutaneous pellets

It’s important to be aware of the potential risks associated with HRT, which may include an increased likelihood of certain cardiovascular problems, prostate problems, and sleep apnea. If you would like to explore HRT, consider contacting Fountain HRT to begin the process, as they are one of the best online TRT clinics currently on the market.


A lot of people don’t want to use supplements or other means to increase their testosterone levels, so the question usually asked is, how to boost testosterone levels naturally?

Eating a balanced diet consisting of various nutrient-dense foods is vital to support testosterone production. The first consideration is to consume enough calories to meet your energy requirements. Healthy fats should also be prioritized. These may include avocados, almonds, seeds, and olive oil.

Consuming a sufficient amount of protein will facilitate testosterone production. Includes such high-quality protein sources as chicken, fish, lean meats, lentils, and dairy. Essential micronutrients such as zinc (found in meat, shellfish, and legumes), vitamin D (from fatty fish and exposure to the sun), and magnesium (found in nuts, seeds, and leafy greens) all promote testosterone production in the body.

Limiting alcohol intake will help with testosterone production. Overdrinking can play havoc with your hormones, potentially leading to a drop in testosterone levels.

Resistance training has been shown to positively impact testosterone and growth hormone production. High-intensity workouts that feature compound movements and a wide rep range are best. Aim for a well-rounded strength training regimen that works for the major muscle groups twice to three times each week.


Testosterone-boosting nutritional supplements are promoted as all-natural compounds that raise testosterone levels. These supplements frequently include a blend of nutrients, including botanical extracts, vitamins, minerals, and amino acids. However, these components can be of varying quality and dose in various brands and formulations. Furthermore, it’s frequently difficult to pinpoint the precise pathways through which these compounds could affect testosterone levels.

The quality of testosterone-boosting nutritional supplements also varies greatly. When searching for a ‘T’ booster, check the label for the following ingredients, which have research supporting their inclusion:

  • D-Aspartic Acid
  • Zinc
  • Fenugreek
  • Vitamin D
  • Tribulus Terrestris
  • Ashwagandha



There is limited and contradictory evidence that creatine directly impacts testosterone levels. Some studies have seen a small rise in testosterone levels following creatine supplementation, while others have found no appreciable change.

It’s important to remember that any potential impact of taking creatine supplements on testosterone levels will probably be indirect. Instead of directly affecting hormone production, creatine mostly influences energy and muscle function. Creatine supplementation can increase muscle growth and strength, which may indirectly impact hormonal balance and perhaps cause moderate increases in testosterone.

Creatine supplements are used to improve sports and exercise performance and muscular development. Regular weight training, which is frequently linked to creatine supplements, can enhance testosterone production on its own. The workout program, rather than the creatine supplementation itself, may cause any reported rise in testosterone levels.


As we have seen throughout this article, there is very little evidence that creatine can increase testosterone levels at all. However, in a 2006 study, testosterone levels were seen to increase by an average of 22%. This study is a bit of an outer, with other studies showing none or very little increase.


No, creatine does not increase testosterone levels in females. It will improve workout energy and recovery ability in women but will have no effect on testosterone levels.


Limited evidence suggests that creatine supplementation may slightly increase estrogen levels. This occurs through a process called aromatization, the process through which the enzyme aromatase transforms testosterone into estrogen in the liver, testes, fat cells, and other body tissues.

The aromatase enzyme, which adds an aromatase group to the testosterone molecule and converts it into estradiol, the main form of estrogen in the body, is responsible for the conversion of testosterone to estrogen.


No, creatine does not lower testosterone levels. There has been quite a lot of research looking into the effect that creatine has on testosterone levels. The consensus from those studies is that creatine supplementation does not significantly impact testosterone levels in healthy people.

It’s important to remember that everyone reacts differently to supplements, and some people may notice very small changes in their hormone levels. These changes are normally within physiologically normal ranges and do not point to a drop in testosterone.


Creatine is a superstar among gym supplements. It has the ability to help produce more energy during intense training so you can lift more weight, perform more reps, and recover more efficiently. But it will not directly help your body produce more testosterone. For that to happen, you need to be taking a high-quality testosterone-boosting supplement and combine it with a healthy diet and regular, intense exercise.

Our recommendation is to take creatine as a workout performance enhancer and a separate ‘T’ booster to encourage greater natural testosterone production.

Doctor of Medicine and Doctor of Philosophy at University of Columbia

Dr. Michael Bonner, a clinical psychologist in Salisbury, MD, received his MD and Ph.D. from Columbia University in 1967. Dr. Bonner obtained his MD and Ph.D. from Columbia University in 1967. Since retiring from medicine, he has been writing and editing on topics ranging from healthcare policy to basic science.

In addition to his professional accomplishments, Dr. Bonner is a sought-after speaker at academic and industry conferences, where he shares insights from his extensive career in psychology and healthcare. His work bridges the gap between clinical practice and academic research, influencing a new generation of professionals and students.

Health Coach

Brittany Hernandez specializes in assessing supplements, health technologies, and applications. She continually enhances her skills as a health copywriter. With a Bachelor's degree in Translation and Communication and a background in linguistics, Brittany is skilled at converting complex research into accessible, high-quality content. She is highly regarded in the health industry for her keen eye for detail and ability to identify high-quality health and wellness products.


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