The CTSA External Reviewer Exchange Consortium (CEREC): Engagement and Efficacy


What is CEREC?

CEREC was established in 2016 to provide an outlet for obtaining external reviews for CTSA-funded pilot research and to minimize the likelihood of bias and conflicts of interest. CEREC also offers a larger pool of expertise from which to draw precisely matched reviews for scientific lines of inquiry that may not be well represented within the institution receiving the proposal.

This consortium is made up of institutes supported by the NIH National Center for Advancing Translational Sciences (NCATS) Clinical and Translational Science Awards competitively awarded to the medical schools/institutions of higher learning indicated below.

How Does CEREC Work?

When a new round of pilot proposals require review, each participating CTSA identifies and solicits reviewers within their pool of investigators. Investigators who agree to review are then connected to the requesting site for instructions and next steps. Each institution utilizes CEREC a bit differently, from the number of reviews requested per pilot proposal to the logistics of the external review process itself. This flexibility is undoubtedly part of the success of the program. CEREC members stay in touch with emails and monthly teleconferences.

CEREC leverages the resources and knowledge base of nine CTSA hubs across the nation to enable the efficient exchange of reviewer expertise to support internal pilot funding programs.

Through collaboration, CEREC develops strategies that promote methodological excellence, scientific transparency and innovation while minimizing conflict of interest in the review process of applications for pilot funding opportunities.

A recent publication entitled, “The CTSA External Reviewer Exchange Consortium (CEREC): Engagement and Efficacy,” was released on October 2, 2019 describing CEREC’s engagement and efficacy.

Future Direction

CEREC enables the rapid dissemination of innovative approaches to all phases of CTSA pilot program management, from application to closeout. Novel techniques shared at the meeting included using a REDCap system to receive and review pilot applications and using SmartSheet, a cloud-based project management tool, to track pilot projects throughout the award year.

Other ideas addressed how to identify internal and community pilot reviewers, how to expeditiously comply with NCATS prior approval guidelines, and meaningful ways to thank pilot reviewers for their invaluable contributions. CEREC members also discussed potential metrics, beyond those required by NCATS’s Common Metrics initiative, by which to gauge pilot success.

CEREC members finalized their Manual of Procedures (MOP) during their face-to-face meeting on January 2018. CTSA administrators who are interested in receiving a copy or starting a new CEREC group should contact Dr. Margaret Schneider at [email protected].

This work was supported by the following awards from the National Institutes of Health (NCATS): 5UL1TR001855-03 (USC); 5UL1TR001414-04 (UC Irvine); 3UL1TR001414-04S1 (Supplement); 1UL1TR002541-01 (Harvard Catalyst); 5UL1TR001417-04 (University of Alabama at Birmingham); 1U54TR001629-01 (University of Arkansas for Medical Sciences); 5UL1TR002319-02 (University of Washington); 1UL1TR002733-01 (The Ohio State University); 1UL1TR002649-01 (Virginia Commonwealth University); 5UL1TR001436-04 (Medical College of Wisconsin). The following individuals also contributed to the success of CEREC: Gary S. Gray, Angela Schmeckebier, Bonnie Berry, and Christine Zeller.

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  • CTSA External Reviewer Exchange Consortium
  • pilot
  • Funding
  • grant
  • review

Publishing CTSA Program Hub’s Name
University Of California Irvine
University Of Southern California
Ohio State University
University Of Alabama At Birmingham
Harvard Medical School
Medical College Of Wisconsin
Virginia Commonwealth University
University of Arkansas for Medical Sciences
University Of Washington