CTSA-supported researchers discover vitamin C improves health for children of pregnant smokers

Group photo of the team that working on the vitamin C and smoking while pregnant study at OHSU. Team was led by Dr. Cynthia McEvoy.
Cindy McEvoy, M.D., professor of pediatrics in the OHSU School of Medicine and her study team.
Image Credit
OHSU/Christine Torres Hicks

Researchers at Oregon Health & Science University (OHSU) found that vitamin C supplementation to pregnant women unable to quit smoking significantly improves airway function and respiratory health in their offspring at 5 years of age. While previous studies have shown that vitamin C improves airway function in infants, this is the first study to demonstrate whether the improvement in airway function can be maintained through preschool age. 

This work was supported by the Oregon Clinical and Translational Research Institute (OCTRI), which is the Oregon CTSA hub housed at OHSU. Dr. Cindy McEvoy, Professor of Pediatrics in the OHSU School of Medicine, led the team that conducted this work and collaborated with Dr. Cindy Morris, Senior Associate Director of OCTRI and Director of OCTRI Workforce Development. Dr. McEvoy’s work has been supported by several OCTRI pilot awards in the last decade, including an OCTRI Catalyst award in 2014 for the project featured here. 

This study published in November 2022 in JAMA Pediatrics and was featured in MedPage Today

Read more about the team and this work on OHSU News

CTSA Program In Action Goals
Goal 1: Train and Cultivate the Translational Science Workforce
Goal 3: Promote the Integration of Special and Underserved Populations in Translational Research Across the Human Lifespan