Wake Forest School of Medicine

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Wake Forest University Health Sciences

Awards: UL1, KL2

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Non Human Primate Signature Program (NHP)
The NHP goal is to accelerate translational research by providing access to a translational animal model with exceptional relevance to human health. NHPs allow the bidirectional translation of knowledge between scientists and clinicians in the Academic Learning Health System (aLHS). Their similarity to humans makes them ideally suited both to evaluate the relevance of findings from more phylogenetically distant models and as a tool for interpreting clinical observations under controlled conditions. Resources include: 1) a colony of over 300 vervet monkeys with data collected from birth until natural death; 2) a radiation survivor cohort of over 150 rhesus macaque monkeys; 3) state-of-the-art facilities that include a specialized NHP diet kitchen, a neonatal nursery, a large animal surgery facility, the comparative pathology laboratory, and a mitochondrial bioenergetics core laboratory; 4) Access to CT, MR, cardiac MR, PET, ultrasound, x-ray, and MEG; 5) faculty expertise; 6) imaging data repository from >17,000 animals and a comprehensive animal records system with over 2.6M records; and 7) a research colony data and tissue repository that includes phenotypic data.

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