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This poster describes the Mothers Leading Science (MLS) program developed by the University of Minnesota - CTSI and the evaluation of the first cohort, especially as the program has supported the participants during the pandemic. MLS is a year-long leadership development program for research-intensive female faculty in the health sciences who are raising school-age and/or young children. The purpose of this group is to foster professional and personal growth, provide peer mentoring, integrate the dual roles of scientist and mother, and build a network of peers for ongoing support throughout their careers.