Unintended consequences of health information technology: a need for biomedical informatics.
Health information technology (HIT) can address important problems in clinical care and biomedical research. These problems include lack of compliance with clinical practice guidelines , insufficient use of preventative medicine services  and numerous impediments to clinical/translational research . However, front-line patient care information systems that can influence care may worsen outcomes as well as improve them. Increasingly, there is evidence of significant, unintended and deleterious effects of well-meaning HIT efforts . In this paper we present examples of such deleterious effects and argue that: (1) HIT is a tool that can influence health care and biomedicine (for good or ill) and (2) biomedical informatics efforts are needed to ensure that HIT fulfills its promise in biomedicine.